Search Results - "Maas, Roderick P.P.W.M"

The preclinical stage of spinocerebellar ataxias by Maas, Roderick P.P.W.M, van Gaalen, Judith, Klockgether, Thomas, van de Warrenburg, Bart P.C

“…The autosomal dominant spinocerebellar ataxias (SCAs) are a heterogeneous group of degenerative diseases of the cerebellum and connected regions. The discovery…”
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The role of the cerebellum in degenerative ataxias and essential tremor: Insights from noninvasive modulation of cerebellar activity by Maas, Roderick P.P.W.M., Helmich, Rick C.G., Warrenburg, Bart P.C.

“…Over the last three decades, measuring and modulating cerebellar activity and its connectivity with other brain regions has become an emerging research topic…”
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L-Dopa in dystonia: A modern perspective by Maas, Roderick P.P.W.M, Wassenberg, Tessa, Lin, Jean-Pierre, van de Warrenburg, Bart P.C, Willemsen, Michèl A.A.P

“…“Every child exhibiting dystonia merits an L-dopa trial, lest the potentially treatable condition of dopa-responsive dystonia (DRD) is missed” has been a…”
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Neuropsychiatric Symptoms in Rhombencephalosynapsis: A Clinical Report by Schutter, Dennis J.L.G., Doherty, Dan, Phillips, James O., Weiss, Avery H., Maas, Roderick P.P.W.M.

“…Rhombencephalosynapsis (RES) is a hindbrain malformation characterized by a missing cerebellar vermis with apposition or fusion of the cerebellar hemispheres…”
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Cerebellar transcranial direct current stimulation modulates timing but not acquisition of conditioned eyeblink responses in SCA3 patients by Maas, Roderick P.P.W.M., Schutter, Dennis J.L.G., Toni, Ivan, Timmann, Dagmar, van de Warrenburg, Bart P.C.

“…Delay eyeblink conditioning is an extensively studied motor learning paradigm that critically depends on the integrity of the cerebellum. In healthy…”
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Inverse associations between cerebellar inhibition and motor impairment in spinocerebellar ataxia type 3 by Maas, Roderick P.P.W.M., van de Warrenburg, Bart P.C., Schutter, Dennis J.L.G.

“…Cerebellar ataxia generally results from a lesion disrupting the corticopontocerebellar or cerebellothalamocortical tract. The cerebellar inhibition (CBI)…”
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Cognitive Complaints and Their Impact on Daily Life in Patients with Degenerative Cerebellar Disorders by Reumers, Stacha F.I., Schutter, Dennis J.L.G., Maas, Roderick P.P.W.M., de Leeuw, Frank-Erik, Kessels, Roy P.C., van de Warrenburg, Bart P.C.

“…Cognitive and affective sequelae of cerebellar disease are receiving increased attention, but their actual rate of occurrence remains unclear. Complaints may…”
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The Genetic Homogeneity of CAPOS Syndrome: Four New Patients With the c.2452G>A (p.Glu818Lys) Mutation in the ATP1A3 Gene by Maas, Roderick P.P.W.M., MD, Schieving, Jolanda H., MD, Schouten, Meyke, MD, Kamsteeg, Erik-Jan, PhD, van de Warrenburg, Bart P.C., MD, PhD

“…Abstract Background The clinical syndrome of cerebellar ataxia, areflexia, pes cavus, optic atrophy, and sensorineural hearing loss (CAPOS) was first described…”
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Cathodal skin lesions in a tattoo following transcranial direct current stimulation by Maas, Roderick P.P.W.M., van de Warrenburg, Bart P.C., Schutter, Dennis J.L.G.

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Author response: L-Dopa in dystonia: A modern perspective by Maas, Roderick P.P.W.M, van de Warrenburg, Bart P.C, Willemsen, Michèl A.A.P

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Preparing for Disease‐Modification Trials in Degenerative Cerebellar Ataxias: Which Endpoints to Choose? by Maas, Roderick P.P.W.M.

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The cerebellar cognitive affective syndrome scale reveals early neuropsychological deficits in SCA3 patients by Maas, Roderick P. P. W. M., Killaars, Sven, van de Warrenburg, Bart P. C., Schutter, Dennis J. L. G.

“…Background The cerebellar cognitive affective syndrome scale (CCAS-S) was recently developed to detect specific neuropsychological deficits in patients with…”
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Cerebellar Transcranial Direct Current Stimulation in Spinocerebellar Ataxia Type 3: a Randomized, Double-Blind, Sham-Controlled Trial by Maas, Roderick P. P. W. M., Teerenstra, Steven, Toni, Ivan, Klockgether, Thomas, Schutter, Dennis J. L. G., van de Warrenburg, Bart P. C.

“…Repeated sessions of cerebellar anodal transcranial direct current stimulation (tDCS) have been suggested to modulate cerebellar-motor cortex (M1) connectivity…”
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Cerebellar Transcranial Direct Current Stimulation in the Cerebellar Cognitive Affective Syndrome: A Randomized, Double‐Blind, Sham‐Controlled Trial by Reumers, Stacha F.I., Maas, Roderick P.P.W.M., Schutter, Dennis J.L.G., Teerenstra, Steven, Kessels, Roy P.C., de Leeuw, Frank‐Erik, van de Warrenburg, Bart P.C.

“…The cerebellar cognitive affective syndrome (CCAS) encompasses cognitive and affective symptoms in patients with cerebellar disorders, for which no proven…”
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Interindividual differences in posterior fossa morphometry affect cerebellar tDCS-induced electric field strength by Maas, Roderick P.P.W.M., Faber, Jennifer, van de Warrenburg, Bart P.C., Schutter, Dennis J.L.G.

“…•Skin-cerebellum distance is the dominant factor determining cerebellar tDCS-induced electric field strength in healthy adults.•Interindividual differences in…”
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Exploring the clinical meaningfulness of the Scale for the Assessment and Rating of Ataxia: A comparison of patient and physician perspectives at the item level by Maas, Roderick P.P.W.M., van de Warrenburg, Bart P.C.

“…The Scale for the Assessment and Rating of Ataxia (SARA) is commonly used as the primary outcome measure in therapeutic trials. Driven by spontaneous comments…”
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Therapeutic Misestimation in Patients with Degenerative Ataxia: Lessons from a Randomized Controlled Trial by Maas, Roderick P.P.W.M., Warrenburg, Bart P.C.

“…ABSTRACT Background The absence of effective treatments may render patients with degenerative cerebellar ataxias susceptible to a placebo response, which could…”
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Teaching Video Neuro Images : Nine syndrome in inferior paramedian pontine infarction: More than meets the eye by Maas, Roderick P P W M, Verrips, Aad

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Differential Temporal Dynamics of Axial and Appendicular Ataxia in SCA3 by Maas, Roderick P.P.W.M., Teerenstra, Steven, Lima, Manuela, Pires, Paula, Pereira de Almeida, Luís, Gaalen, Judith, Timmann, Dagmar, Infante, Jon, Onyike, Chiadi, Bushara, Khalaf, Jacobi, Heike, Reetz, Kathrin, Santana, Magda M., Afonso Ribeiro, Joana, Hübener‐Schmid, Jeannette, Vries, Jeroen J., Synofzik, Matthis, Schöls, Ludger, Garcia‐Moreno, Hector, Giunti, Paola, Faber, Jennifer, Klockgether, Thomas, Warrenburg, Bart P.C.

“…Background Disease severity in spinocerebellar ataxia type 3 (SCA3) is commonly defined by the Scale for the Assessment and Rating of Ataxia (SARA) sum score,…”
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The potential value of disease-modifying therapy in patients with spinocerebellar ataxia type 1: an early health economic modeling study by van Prooije, Teije, Ruigrok, Sanne, van den Berkmortel, Niels, Maas, Roderick P. P. W. M., Wijn, Stan, van Roon-Mom, Willeke M. C., van de Warrenburg, Bart, Grutters, Janneke P. C.

“…Objective There currently is no disease-modifying therapy for spinocerebellar ataxia type 1 (SCA1). Genetic interventions, such as RNA-based therapies, are…”
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