Search Results - "Maas, N."
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Pertussis resurgence: waning immunity and pathogen adaptation - two sides of the same coin
Published in Epidemiology and infection (01-04-2014)“…Pertussis or whooping cough has persisted and resurged in the face of vaccination and has become one of the most prevalent vaccine-preventable diseases in…”
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Glioblastoma hijacks microglial gene expression to support tumor growth
Published in Journal of neuroinflammation (16-04-2020)“…Glioblastomas are the most common and lethal primary brain tumors. Microglia, the resident immune cells of the brain, survey their environment and respond to…”
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Examining prestructured β-actin peptides as substrates of histidine methyltransferase SETD3
Published in Scientific reports (02-11-2024)“…The N τ -His73 methylation of β-actin by histidine methyltransferase SETD3 is required for the integrity of the cellular cytoskeleton. Modulation of SETD3…”
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Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis
Published in Acta neuropathologica (01-01-2021)“…Diffuse IDH-mutant astrocytoma mostly occurs in adults and carries a favorable prognosis compared to IDH-wildtype malignant gliomas. Acquired mismatch repair…”
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Trimethyllysine: From Carnitine Biosynthesis to Epigenetics
Published in International journal of molecular sciences (11-12-2020)“…Trimethyllysine is an important post-translationally modified amino acid with functions in the carnitine biosynthesis and regulation of key epigenetic…”
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Comparative Analysis Identifies Similarities between the Human and Murine Microglial Sensomes
Published in International journal of molecular sciences (02-02-2021)“…One of the essential functions of microglia is to continuously sense changes in their environment and adapt to those changes. For this purpose, they use a set…”
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Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1
Published in Acta neuropathologica (01-07-2021)“…Glioblastoma IDH-wildtype presents with a wide histological spectrum. Some features are so distinctive that they are considered as separate histological…”
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Severe underestimation of pertussis related hospitalizations and deaths in the Netherlands: A capture-recapture analysis
Published in Vaccine (24-07-2017)“…•Pertussis hospitalizations and deaths are underestimated, especially in >2y olds.•This underestimation is important in the evaluation of vaccination…”
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Quantification and size-profiling of extracellular vesicles using tunable resistive pulse sensing
Published in Journal of visualized experiments (19-10-2014)“…Extracellular vesicles (EVs), including 'microvesicles' and 'exosomes', are highly abundant in bodily fluids. Recent years have witnessed a tremendous increase…”
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Safety of vaccination against influenza A (H1N1) during pregnancy in the Netherlands: results on pregnancy outcomes and infant's health: cross‐sectional linkage study
Published in BJOG : an international journal of obstetrics and gynaecology (01-04-2016)“…Objective This study aims to assess the safety of Influenza A(H1N1), vaccination administered during the second and third trimester and containing MF59 and…”
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No evidence found for an increased risk of long-term fatigue following human papillomavirus vaccination of adolescent girls
Published in Vaccine (29-10-2018)“…In 2013, the Netherlands Pharmacovigilance Center Lareb published an overview of reports of long-lasting fatigue following bivalent HPV-vaccination (2vHPV)…”
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Genotype-phenotype correlation in 21 patients with Wolf-Hirschhorn syndrome using high resolution array comparative genome hybridisation (CGH)
Published in Journal of medical genetics (01-02-2008)“…The Wolf-Hirschhorn syndrome (WHS) is usually caused by terminal deletions of the short arm of chromosome 4 and is phenotypically defined by growth and mental…”
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A standardized method to determine the concentration of extracellular vesicles using tunable resistive pulse sensing
Published in Journal of extracellular vesicles (01-01-2016)“…Understanding the pathogenic role of extracellular vesicles (EVs) in disease and their potential diagnostic and therapeutic utility is extremely reliant on…”
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Emerging patterns of cryptic chromosomal imbalance in patients with idiopathic mental retardation and multiple congenital anomalies: a new series of 140 patients and review of published reports
Published in Journal of medical genetics (01-08-2006)“…Background: Chromosomal abnormalities are a major cause of mental retardation and multiple congenital anomalies (MCA/MR). Screening for these chromosomal…”
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Submicroscopic chromosomal imbalances detected by array-CGH are a frequent cause of congenital heart defects in selected patients
Published in European heart journal (01-11-2007)“…Aims Congenital heart defects (CHDs) are frequently caused by chromosomal imbalances, especially when associated with additional malformations, dysmorphism, or…”
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Performance of a bedside test for tetanus immunity: results of a cross-sectional study among three EDs in the Netherlands in 2012-2013
Published in Emergency medicine journal : EMJ (01-11-2016)“…Despite sustained high vaccination coverage and a national guideline by the Health Council (HC-guideline) on tetanus postexposure prophylaxis (T-PEP), tetanus…”
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Multidimensional communication in the microenvirons of glioblastoma
Published in Nature reviews. Neurology (01-08-2018)“…Glioblastomas are heterogeneous and invariably lethal tumours. They are characterized by genetic and epigenetic variations among tumour cells, which makes the…”
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Extracellular Vesicles: Unique Intercellular Delivery Vehicles
Published in Trends in cell biology (01-03-2017)“…Extracellular vesicles (EVs) are a heterogeneous collection of membrane-bound carriers with complex cargoes including proteins, lipids, and nucleic acids…”
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Reported adverse events in girls aged 13–16 years after vaccination with the human papillomavirus (HPV)-16/18 vaccine in the Netherlands
Published in Vaccine (20-06-2011)“…Abstract In 2009, human papillomavirus (HPV) vaccination was offered to girls born in 1993–1996 in a catch-up campaign, followed in 2010 by the implementation…”
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Quantification of nanosized extracellular membrane vesicles with scanning ion occlusion sensing
Published in Nanomedicine (London, England) (01-09-2013)“…Cells secrete different types of membrane vesicles (MVs), which may act as important entities in normal human physiology and in various pathological processes…”
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