Search Results - "Maarten C. Bosland"
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A perspective on the role of estrogen in hormone-induced prostate carcinogenesis
Published in Cancer letters (28-06-2013)“…Highlights ► Prostate cancer is likely caused by androgens in concert with estradiol and estrogen metabolites. ► Androgen-receptor mediated activity of…”
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2
Evaluation of Bisphenol A (BPA) Exposures on Prostate Stem Cell Homeostasis and Prostate Cancer Risk in the NCTR-Sprague-Dawley Rat: An NIEHS/FDA CLARITY-BPA Consortium Study
Published in Environmental health perspectives (01-11-2018)“…Previous work determined that early life exposure to low-dose Bisphenol A (BPA) increased rat prostate cancer risk with aging. Herein, we report on…”
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3
DDX41 is needed for pre- and postnatal hematopoietic stem cell differentiation in mice
Published in Stem cell reports (12-04-2022)“…DDX41 is a tumor suppressor frequently mutated in human myeloid neoplasms, but whether it affects hematopoiesis is unknown. Using a knockout mouse, we…”
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4
Potential New Approaches for Prostate Cancer Management in Resource-Limited Countries in Africa
Published in Annals of global health (01-01-2023)“…Prostate cancer is a major male malignancy in many sub-Saharan countries in Africa. Because of resource limitations, screening, early detection, diagnosis, and…”
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5
Developing a global medicine student pre- and post-travel curriculum
Published in BMC medical education (06-10-2023)“…The popularity of short-term global health experiences amongst US medical students has been increasing. However, it remains a challenge for medical schools to…”
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6
Z-Endoxifen prevents aggressive mammary cancers in mice by inhibiting cell proliferation and creating a tumor suppressive microenvironment
Published in Biomedicine & pharmacotherapy (01-06-2023)“…Aggressive estrogen receptor (ER) positive breast cancer is frequently tamoxifen-resistant; alternative endocrine approaches exist for therapy, but not for…”
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Differential effects of genistein on prostate cancer cells depend on mutational status of the androgen receptor
Published in PloS one (22-10-2013)“…Blocking the androgen receptor (AR) activity is the main goal of therapies for advanced prostate cancer (PCa). However, relapse with a more aggressive, hormone…”
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8
Soy Consumption and Colorectal Cancer Risk in Humans: A Meta-Analysis
Published in Cancer epidemiology, biomarkers & prevention (01-01-2010)“…The purpose of the present study was to determine the relationship between soy consumption and colorectal cancer risk in humans by conducting a meta-analysis…”
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Vitamin K and its analogs: Potential avenues for prostate cancer management
Published in Oncotarget (22-08-2017)“…Epidemiological studies have demonstrated a relationship between cancer incidence and dietary habits. Especially intake of certain essential nutrients like…”
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10
Survivin-Sodium Iodide Symporter Reporter as a Non-Invasive Diagnostic Marker to Differentiate Uterine Leiomyosarcoma from Leiomyoma
Published in Cells (Basel, Switzerland) (01-12-2023)“…Leiomyosarcoma (LMS) has been challenging to diagnose because of limitations in clinical and radiographic predictors, as well as the lack of reliable serum or…”
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Soy isoflavone supplementation for breast cancer risk reduction: a randomized phase II trial
Published in Cancer prevention research (Philadelphia, Pa.) (01-02-2012)“…Soy isoflavone consumption may protect against breast cancer development. We conducted a phase IIB trial of soy isoflavone supplementation to examine its…”
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12
Hepatoma-derived growth factor: A survival-related protein in prostate oncogenesis and a potential target for vitamin K2
Published in Urologic oncology (01-11-2016)“…Abstract Hepatoma-derived growth factor (HDGF) is a heparin-binding growth factor, which has previously been shown to be expressed in a variety of cancers…”
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13
Prostate cancer in low- and middle-income countries - challenges and opportunities
Published in Prostate cancer and prostatic diseases (28-09-2024)Get full text
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14
Novel insight in estrogen homeostasis and bioactivity in the ACI rat model of estrogen-induced mammary gland carcinogenesis
Published in Archives of toxicology (01-07-2019)“…Despite being widely used to investigate 17β-estradiol (E2)-induced mammary gland (MG) carcinogenesis and prevention thereof, estrogen homeostasis and its…”
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15
Soy isoflavones and prostate cancer: A review of molecular mechanisms
Published in The Journal of steroid biochemistry and molecular biology (01-03-2014)“…•We reviewed of all anti-carcinogenic effects of soy isoflavones in prostate cancer.•We discussed the traditional growth and apoptotic pathways in prostate…”
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16
Conditional inactivation of p53 in mouse ovarian surface epithelium does not alter MIS driven Smad2-dominant negative epithelium-lined inclusion cysts or teratomas
Published in PloS one (31-05-2013)“…Epithelial ovarian cancer is the most lethal gynecological malignancy among US women. The etiology of this disease, although poorly understood, may involve the…”
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17
Testosterone Treatment Is a Potent Tumor Promoter for the Rat Prostate
Published in Endocrinology (Philadelphia) (01-12-2014)“…Testosterone is increasingly prescribed to middle aged and older men, but the safety of this treatment has been called into question, and the possible risk of…”
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18
Sodium arsenite does not affect prostate carcinogenesis in a chemically-hormonally-induced rat model
Published in Toxicology (Amsterdam) (30-05-2022)“…There is epidemiologic evidence to suggest that arsenic exposure is associated with risk of prostate cancer incidence and mortality. There are no studies…”
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Dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced prostate carcinogenesis in CYP1A-humanized mice
Published in Cancer prevention research (Philadelphia, Pa.) (01-07-2012)“…To develop a relevant mouse model for prostate cancer prevention research, we administered a dietary carcinogen,…”
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Vitamin K2, a Naturally Occurring Menaquinone, Exerts Therapeutic Effects on Both Hormone-Dependent and Hormone-Independent Prostate Cancer Cells
Published in Evidence-based complementary and alternative medicine (01-01-2013)“…In recent years, several studies have shown that vitamin k2 (VK2) has anticancer activity in a variety of cancer cells. The antitumor effects of VK2 in…”
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