Search Results - "Maaker, Michiel de"

Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial by Voorwerk, Leonie, Slagter, Maarten, Horlings, Hugo M., Sikorska, Karolina, van de Vijver, Koen K., de Maaker, Michiel, Nederlof, Iris, Kluin, Roelof J. C., Warren, Sarah, Ong, SuFey, Wiersma, Terry G., Russell, Nicola S., Lalezari, Ferry, Schouten, Philip C., Bakker, Noor A. M., Ketelaars, Steven L. C., Peters, Dennis, Lange, Charlotte A. H., van Werkhoven, Erik, van Tinteren, Harm, Mandjes, Ingrid A. M., Kemper, Inge, Onderwater, Suzanne, Chalabi, Myriam, Wilgenhof, Sofie, Haanen, John B. A. G., Salgado, Roberto, de Visser, Karin E., Sonke, Gabe S., Wessels, Lodewyk F. A., Linn, Sabine C., Schumacher, Ton N., Blank, Christian U., Kok, Marleen

“…The efficacy of programmed cell death protein 1 (PD-1) blockade in metastatic triple-negative breast cancer (TNBC) is low 1 – 5 , highlighting a need for…”
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Mechanisms of Therapy Resistance in Patient-Derived Xenograft Models of BRCA1-Deficient Breast Cancer by Ter Brugge, Petra, Kristel, Petra, van der Burg, Eline, Boon, Ute, de Maaker, Michiel, Lips, Esther, Mulder, Lennart, de Ruiter, Julian, Moutinho, Catia, Gevensleben, Heidrun, Marangoni, Elisabetta, Majewski, Ian, Józwiak, Katarzyna, Kloosterman, Wigard, van Roosmalen, Markus, Duran, Karen, Hogervorst, Frans, Turner, Nick, Esteller, Manel, Cuppen, Edwin, Wesseling, Jelle, Jonkers, Jos

“…Although BRCA1-deficient tumors are extremely sensitive to DNA-damaging drugs and poly(ADP-ribose) polymerase (PARP) inhibitors, recurrences do occur and,…”
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Five-Year Results of the Preoperative Accelerated Partial Breast Irradiation (PAPBI) Trial by Bosma, Sophie C.J., Leij, Femke, Vreeswijk, Sandra, Maaker, Michiel de, Wesseling, Jelle, Vijver, Marc van de, Scholten, Astrid, Rivera, Sofia, Bourgier, Celine, Auzac, Guillaume, Foukakis, Theodoros, Lekberg, Tobias, Bongard, Desiree, Loo, Claudette, Rutgers, Emiel, Bartelink, Harry, Elkhuizen, Paula H.M.

“…In this multicenter phase 2 feasibility study, we investigated the impact of preoperative accelerated partial breast irradiation (PAPBI) on local control,…”
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Comprehensive evaluation of methods to assess overall and cell-specific immune infiltrates in breast cancer by Nederlof, Iris, De Bortoli, Davide, Bareche, Yacine, Nguyen, Bastien, de Maaker, Michiel, Hooijer, Gerrit K J, Buisseret, Laurence, Kok, Marleen, Smid, Marcel, Van den Eynden, Gert G G M, Brinkman, Arie B, Hudecek, Jan, Koster, Jan, Sotiriou, Christos, Larsimont, Denis, Martens, John W M, van de Vijver, Marc J, Horlings, Hugo M, Salgado, Roberto, Biganzoli, Elia, Desmedt, Christine

“…Breast cancer (BC) immune infiltrates play a critical role in tumor progression and response to treatment. Besides stromal tumor infiltrating lymphocytes…”
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Molecular detection of minimal residual cancer in surgical margins of head and neck cancer patients by Graveland, A Peggy, de Maaker, Michiel, Braakhuis, Boudewijn J M, de Bree, Remco, Eerenstein, Simone E J, Bloemena, Elisabeth, Leemans, C René, Brakenhoff, Ruud H

“…A great disappointment in head and neck cancer surgery is that 10-30% of head and neck squamous cell carcinoma (HNSCC) patients develop local recurrences…”
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EP1156: ARE BIOMARKERS IN PANCREATIC JUICE USEFUL TO DIFFERENTIATE BETWEEN CHRONIC PANCREATITIS AND IPMN WITH MAIN DUCT INVOLVEMENT? by Hoogenboom, Sanne A., Gorris, Myrte, Maaker, Michiel de, Halfwerk, Hans, Lekkerkerker, Selma, Wielenga, Mattheus C., Besselink, Marc G., Hooft, Jeanin E. Van, Dijk, Frederike

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Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer by Lips, Esther H., Kumar, Tapsi, Megalios, Anargyros, Visser, Lindy L., Sheinman, Michael, Fortunato, Angelo, Shah, Vandna, Hoogstraat, Marlous, Sei, Emi, Mallo, Diego, Roman-Escorza, Maria, Ahmed, Ahmed A., Xu, Mingchu, van den Belt-Dusebout, Alexandra W., Brugman, Wim, Casasent, Anna K., Clements, Karen, Davies, Helen R., Fu, Liping, Grigoriadis, Anita, Hardman, Timothy M., King, Lorraine M., Krete, Marielle, Kristel, Petra, de Maaker, Michiel, Maley, Carlo C., Marks, Jeffrey R., Menegaz, Brian A., Mulder, Lennart, Nieboer, Frank, Nowinski, Salpie, Pinder, Sarah, Quist, Jelmar, Salinas-Souza, Carolina, Schaapveld, Michael, Schmidt, Marjanka K., Shaaban, Abeer M., Shami, Rana, Sridharan, Mathini, Zhang, John, Stobart, Hilary, Collyar, Deborah, Nik-Zainal, Serena, Wessels, Lodewyk F. A., Hwang, E. Shelley, Navin, Nicholas E., Futreal, P. Andrew, Thompson, Alastair M., Wesseling, Jelle, Sawyer, Elinor J.

“…Ductal carcinoma in situ (DCIS) is the most common form of preinvasive breast cancer and, despite treatment, a small fraction (5–10%) of DCIS patients develop…”
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Response to Preoperative Radiation Therapy in Relation to Gene Expression Patterns in Breast Cancer Patients by Bosma, Sophie C.J., Hoogstraat, Marlous, van der Leij, Femke, de Maaker, Michiel, Wesseling, Jelle, Lips, Esther, Loo, Claudette E., Rutgers, Emiel J., Elkhuizen, Paula H.M., Bartelink, Harry, van de Vijver, Marc J.

“…We aimed to study radiation-induced gene expression changes and to identify differences in gene expression between patients with and without response to…”
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A case-control study to identify molecular risk factors for local recurrence in young breast cancer patients by Bosma, Sophie C.J., Hoogstraat, Marlous, van Werkhoven, Erik, de Maaker, Michiel, van der Leij, Femke, Elkhuizen, Paula H.M., Fourquet, Alain, Poortmans, Philip, Boersma, Liesbeth J., Bartelink, Harry, van de Vijver, Marc J.

“…•Primary tumours and local recurrences showed similar genomic profiles.•Several differences between recurring and non-recurring tumors were observed.•No…”
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Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial by Nederlof, Iris, Isaeva, Olga I., de Graaf, Manon, Gielen, Robbert C. A. M., Bakker, Noor A. M., Rolfes, Adrianne L., Garner, Hannah, Boeckx, Bram, Traets, Joleen J. H., Mandjes, Ingrid A. M., de Maaker, Michiel, van Brussel, Thomas, Chelushkin, Maksim, Champanhet, Elisa, Lopez-Yurda, Marta, van de Vijver, Koen, van den Berg, José G., Hofland, Ingrid, Klioueva, Natasja, Mann, Ritse M., Loo, Claudette E., van Duijnhoven, Frederieke H., Skinner, Victoria, Luykx, Sylvia, Kerver, Emile, Kalashnikova, Ekaterina, van Dongen, Marloes G. J., Sonke, Gabe S., Linn, Sabine C., Blank, Christian U., de Visser, Karin E., Salgado, Roberto, Wessels, Lodewyk F. A., Drukker, Caroline A., Schumacher, Ton N., Horlings, Hugo M., Lambrechts, Diether, Kok, Marleen

“…Immune checkpoint inhibition (ICI) with chemotherapy is now the standard of care for stage II–III triple-negative breast cancer; however, it is largely unknown…”
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Corrigendum to "A case-control study to identify molecular risk factors for local recurrence in young breast cancer patients" [Radiother Oncol 156 (2021) 127-135] by Bosma, Sophie C.J., Hoogstraat, Marlous, van Werkhoven, Erik, de Maaker, Michiel, van der Leij, Femke, Elkhuizen, Paula H.M., Fourquet, Alain, Poortmans, Philip, Boersma, Liesbeth J., Bartelink, Harry, van de Vijver, Marc J.

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Abstract 4348: In depth molecular analysis of 183 primary DCIS lesions and 78 subsequent invasive breast cancers by Visser, Lindy, Hoogstraat, Marlous, Kucukosmanogl, Asli, Nieboer, Frank, Maaker, Michiel de, Kristel, Petra, Mulder, Lennart, Elshof, Lotte, Leeuwen, Flora van, Rutgers, Emiel, Schmidt, Marjanka K., Lips, Esther, Wesseling, Jelle

“…Abstract Background. Ductal carcinoma in situ (DCIS) is a potential precursor of invasive breast cancer (IBC). As we are currently unable to predict which DCIS…”
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Abstract 751: Ductal carcinoma in situ of the breast: Cancer precursor or not by Visser, Lindy, Hoogstraat, Marlous, Bismeijer, Tycho, Elshof, Lotte, Vijver, Koen van de, Groen, Emilie, Almekinders, Mathilde, Sanders, Joyce, Bierman, Carolien, Peters, Dennis, Hofland, Ingrid, Nieboer, Frank, Maaker, Michiel de, Kristel, Petra, Mulder, Lennart, Broeks, Annegien, Schaapveld, Michael, Schmidt, Marjanka, Wessels, Lodewyk, Lips, Esther, Wesseling, Jelle

“…Abstract Background. Ductal carcinoma in situ (DCIS) is a potential precursor of invasive breast cancer (IBC). However, the natural course of a particular DCIS…”
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Molecular screening of oral precancer by Graveland, A. Peggy, Bremmer, Jantine F, de Maaker, Michiel, Brink, Arjen, Cobussen, Paul, Zwart, Meindert, Braakhuis, Boudewijn J.M, Bloemena, Elisabeth, van der Waal, Isaäc, Leemans, C. René, Brakenhoff, Ruud H

“…Summary Objectives Early detection and treatment of high risk premalignant mucosal changes of the oral cavity, will expectedly improve survival and reduce…”
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Adaptive phase II randomized trial of nivolumab after induction treatment in triple negative breast cancer (TONIC trial): Final response data stage I and first translational data by Kok, Marleen, Voorwerk, Leonie, Horlings, Hugo, Sikorska, Karolina, van der Vijver, Koen, Slagter, Maarten, Warren, Sarah, Ong, SuFey, Wiersma, Terry, Russell, Nicola, Lalezari, Ferry, de Maaker, Michiel, Kemper, Inge, Mandjes, Ingrid A., Chalabi, Myriam, Sonke, Gabe S., Salgado, Roberto, Linn, Sabine C., Schumacher, Ton, Blank, Christian U.

“…Abstract only…”
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Publisher Correction: Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial by Voorwerk, Leonie, Slagter, Maarten, Horlings, Hugo M., Sikorska, Karolina, van de Vijver, Koen K., de Maaker, Michiel, Nederlof, Iris, Kluin, Roelof J. C., Warren, Sarah, Ong, SuFey, Wiersma, Terry G., Russell, Nicola S., Lalezari, Ferry, Schouten, Philip C., Bakker, Noor A. M., Ketelaars, Steven L. C., Peters, Dennis, Lange, Charlotte A. H., van Werkhoven, Erik, van Tinteren, Harm, Mandjes, Ingrid A. M., Kemper, Inge, Onderwater, Suzanne, Chalabi, Myriam, Wilgenhof, Sofie, Haanen, John B. A. G., Salgado, Roberto, de Visser, Karin E., Sonke, Gabe S., Wessels, Lodewyk F. A., Linn, Sabine C., Schumacher, Ton N., Blank, Christian U., Kok, Marleen

“…In the version of this article originally published, there was an error in Fig. 3j. A label on the heatmap read “TGF-α signaling via NF-κB”. It should have…”
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PD-L1 blockade in combination with carboplatin as immune induction in metastatic lobular breast cancer: the GELATO trial by Voorwerk, Leonie, Isaeva, Olga I, Horlings, Hugo M, Balduzzi, Sara, Chelushkin, Maksim, Bakker, Noor A M, Champanhet, Elisa, Garner, Hannah, Sikorska, Karolina, Loo, Claudette E, Kemper, Inge, Mandjes, Ingrid A M, de Maaker, Michiel, van Geel, Jasper J L, Boers, Jorianne, de Boer, Maaike, Salgado, Roberto, van Dongen, Marloes G J, Sonke, Gabe S, de Visser, Karin E, Schumacher, Ton N, Blank, Christian U, Wessels, Lodewyk F A, Jager, Agnes, Tjan-Heijnen, Vivianne C G, Schröder, Carolien P, Linn, Sabine C, Kok, Marleen

“…Invasive lobular breast cancer (ILC) is the second most common histological breast cancer subtype, but ILC-specific trials are lacking. Translational research…”
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Identification of Lethal microRNAs Specific for Head and Neck Cancer by LINDENBERGH-VAN DER PLAS, Marlon, MARTENS-DE KEMP, Sanne R, DE MAAKER, Michiel, VAN WIERINGEN, Wessel N, YLSTRA, Bauke, AGAMI, Reuven, CERISOLI, Francesco, LEEMANS, C. René, BRAAKHUIS, Boudewijn J. M, BRAKENHOFF, Ruud H

“…The prognosis of head and neck squamous cell carcinomas (HNSCC) remains disappointing and the development of novel anti-cancer agents is urgently awaited. We…”
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Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials by Hudeček, Jan, Voorwerk, Leonie, van Seijen, Maartje, Nederlof, Iris, de Maaker, Michiel, van den Berg, Jose, van de Vijver, Koen K, Sikorska, Karolina, Adams, Sylvia, Demaria, Sandra, Viale, Giuseppe, Nielsen, Torsten O, Badve, Sunil S, Michiels, Stefan, Symmans, William Fraser, Sotiriou, Christos, Rimm, David L, Hewitt, Stephen M, Denkert, Carsten, Loibl, Sibylle, Loi, Sherene, Bartlett, John M S, Pruneri, Giancarlo, Dillon, Deborah A, Cheang, Maggie C U, Tutt, Andrew, Hall, Jacqueline A, Kos, Zuzana, Salgado, Roberto, Kok, Marleen, Horlings, Hugo M

“…Stromal tumor-infiltrating lymphocytes (sTILs) are a potential predictive biomarker for immunotherapy response in metastatic triple-negative breast cancer…”
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Molecular diagnosis of minimal residual disease in head and neck cancer patients by Graveland, A. Peggy, Braakhuis, Boudewijn J. M., Eerenstein, Simone E. J., de Bree, Remco, Bloemena, Elisabeth, de Maaker, Michiel, van den Brekel, Michiel W. M., Dijk, Frederike, Mesker, Wilma E., Tanke, Hans J., Leemans, C. Rene, Brakenhoff, Ruud H.

“…Aim Locoregional recurrences and distant metastases in adequately treated head and neck squamous cell carcinoma (HNSCC) patients have a dismal effect on…”
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