Search Results - "Małgorzata, Iciek"

Biological properties of garlic and garlic-derived organosulfur compounds by Iciek, Małgorzata, Kwiecień, Inga, Włodek, Lidia

“…Medicinal properties of garlic (Allium sativum) have been widely known and used since ancient times till the present. Garlic enhances immune functions and has…”
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Chemistry and Biochemistry Aspects of the 4-Hydroxy-2,3-trans-nonenal by Bilska-Wilkosz, Anna, Iciek, Małgorzata, Górny, Magdalena

“…4-hydroxy-2,3-trans-nonenal (C H O ), also known as 4-hydroxy- -nonenal (C H O ; HNE) is an α,β-unsaturated hydroxyalkenal. HNE is a major aldehyde, formed in…”
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Reactive Sulfur Species (RSS) in Physiological and Pathological Conditions and in Therapy by Bilska-Wilkosz, Anna, Iciek, Małgorzata

“…Sulfur is a multivalent and nonmetallic chemical element with the symbol S and the atomic number 16 [...]…”
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The Role of Hemoproteins: Hemoglobin, Myoglobin and Neuroglobin in Endogenous Thiosulfate Production Processes by Bilska-Wilkosz, Anna, Iciek, Małgorzata, Górny, Magdalena, Kowalczyk-Pachel, Danuta

“…Thiosulfate formation and biodegradation processes link aerobic and anaerobic metabolism of cysteine. In these reactions, sulfite formed from thiosulfate is…”
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Glutathione Deficiency and Alterations in the Sulfur Amino Acid Homeostasis during Early Postnatal Development as Potential Triggering Factors for Schizophrenia-Like Behavior in Adult Rats by Górny, Magdalena, Wnuk, Agnieszka, Kamińska, Adrianna, Kamińska, Kinga, Chwatko, Grażyna, Bilska-Wilkosz, Anna, Iciek, Małgorzata, Kajta, Małgorzata, Rogóż, Zofia, Lorenc-Koci, Elżbieta

“…Impaired glutathione (GSH) synthesis and dopaminergic transmission are important factors in the pathophysiology of schizophrenia. Our research aimed to assess…”
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Reactive Sulfur Compounds in the Fight against COVID-19 by Iciek, Małgorzata, Bilska-Wilkosz, Anna, Kozdrowicki, Michał, Górny, Magdalena

“…The SARS-CoV-2 coronavirus pandemic outbreak in 2019 resulted in the need to search for an effective and safe strategy for treating infected patients,…”
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Inactivation of Aldehyde Dehydrogenase by Disulfiram in the Presence and Absence of Lipoic Acid or Dihydrolipoic Acid: An in Vitro Study by Bilska-Wilkosz, Anna, Górny, Magdalena, Iciek, Małgorzata

“…The inhibition of aldehyde dehydrogenase (ALDH) by disulfiram (DSF) in vitro can be prevented and/or reversed by dithiothreitol (DTT), which is a well-known…”
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Alterations in the Antioxidant Enzyme Activities in the Neurodevelopmental Rat Model of Schizophrenia Induced by Glutathione Deficiency during Early Postnatal Life by Górny, Magdalena, Bilska-Wilkosz, Anna, Iciek, Małgorzata, Hereta, Marta, Kamińska, Kinga, Kamińska, Adrianna, Chwatko, Grażyna, Rogóż, Zofia, Lorenc-Koci, Elżbieta

“…The aim of the present study was to assess the effects of l-buthionine-(S,R)-sulfoximine (BSO), a glutathione (GSH) synthesis inhibitor, and GBR 12909, a…”
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Alpha lipoic acid protects the heart against myocardial post ischemia-reperfusion arrhythmias via KATP channel activation in isolated rat hearts by Dudek, Magdalena, Knutelska, Joanna, Bednarski, Marek, Nowiński, Leszek, Zygmunt, Małgorzata, Bilska-Wilkosz, Anna, Iciek, Małgorzata, Otto, Monika, Żytka, Iwona, Sapa, Jacek, Włodek, Lidia, Filipek, Barbara

“…The cardiovascular effects of alpha lipoic acid were evaluated in isolated rat hearts exposed to ischemia-reperfusion injury in vitro. Alpha-lipoic acid raised…”
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Acceleration of Anaerobic Cysteine Transformations to Sulfane Sulfur Consequent to γ-Glutamyl Transpeptidase Inhibition by Kwiecień, Inga, Iciek, Małgorzata, Włodek, Lidia

“…Toxicity of drugs and radiation in the cells is largely dependent on the level of thiols. In the present studies, an attempt has been made to inhibit…”
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Sulfane sulfur - new findings on an old topic by Iciek, Malgorzata, Bilska-Wilkosz, Anna, Górny, Magdalena

“…Sulfane sulfur is a divalent sulfur atom bonded to another sulfur which is very reactive and labile. Compounds containing this reactive sulfur include…”
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Yohimbine Alleviates Oxidative Stress and Suppresses Aerobic Cysteine Metabolism Elevated in the Rat Liver of High-Fat Diet-Fed Rats by Iciek, Małgorzata, Górny, Magdalena, Kotańska, Magdalena, Bilska-Wilkosz, Anna, Kaczor-Kamińska, Marta, Zagajewski, Jacek

“…Yohimbine is a small indole alkaloid derived from the bark of the yohimbe tree with documented biological activity, including anti-inflammatory, erectile…”
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Reactive sulfur species and their significance in health and disease by Iciek, Małgorzata, Bilska-Wilkosz, Anna, Kozdrowicki, Michał, Górny, Magdalena

“…Abstract Reactive sulfur species (RSS) have been recognized in the last two decades as very important molecules in redox regulation. They are involved in…”
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Plasma levels of total, free and protein bound thiols as well as sulfane sulfur in different age groups of rats by Iciek, Małgorzata, Chwatko, Grazyna, Lorenc-Koci, Elzbieta, Bald, Edward, Włodek, Lidia

“…The redox status of plasma thiols can be a diagnostic indicator of different pathological states. The aim of this study was to identify the age dependent…”
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Lipoic Acid as a Possible Pharmacological Source of Hydrogen Sulfide/Sulfane Sulfur by Bilska-Wilkosz, Anna, Iciek, Małgorzata, Kowalczyk-Pachel, Danuta, Górny, Magdalena, Sokołowska-Jeżewicz, Maria, Włodek, Lidia

“…The aim of the present study was to verify whether lipoic acid (LA) itself is a source of H₂S and sulfane sulfur. It was investigated in vitro…”
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Treatment with aripiprazole and N‐acetylcysteine affects anaerobic cysteine metabolism in the hippocampus and reverses schizophrenia‐like behavior in the neurodevelopmental rat model of schizophrenia by Górny, Magdalena, Bilska‐Wilkosz, Anna, Iciek, Małgorzata, Rogóż, Zofia, Lorenc‐Koci, Elżbieta

“…Preclinical and clinical studies have shown that the antipsychotic drug aripiprazole and the antioxidant N‐acetylcysteine have unique biological properties…”
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S-sulfhydration as a cellular redox regulation by Iciek, Małgorzata, Kowalczyk-Pachel, Danuta, Bilska-Wilkosz, Anna, Kwiecień, Inga, Górny, Magdalena, Włodek, Lidia

“…For many years reactive oxygen and nitrogen species (ROS and RNS) have been recognized as key messengers in the process of thiol-based redox regulation…”
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Is aldehyde dehydrogenase inhibited by sulfur compounds? In vitro and in vivo studies by Iciek, Malgorzata, Górny, Magdalena, Bilska-Wilkosz, Anna, Kowalczyk-Pachel, Danuta

“…Aldehyde dehydrogenase (ALDH) catalyzes the critical step of ethanol metabolism, i.e.  transformation of toxic acetaldehyde to acetic acid. It is a redox…”
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Thiol levels, protein carbonylation and anaerobic sulfur metabolism in erythrocytes of peritoneal dialysis and predialysis patients by WŁODEK, PRZEMYSŁAW, MARCYKIEWICZ, BERNADETA, ICIEK, MAŁGORZATA, SULIGA, MAŁGORZATA, SMOLEŃSKI, OLGIERD, KOWALCZYK-PACHEL, DANUTA

“…ABSTRACT Aim:  The goal of the present study was to investigate the changes in sulfur metabolism in erythrocytes of end‐stage renal failure patients. Methods: …”
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Cysteine Metabolism and Oxidative Processes in the Rat Liver and Kidney after Acute and Repeated Cocaine Treatment by Kowalczyk-Pachel, Danuta, Iciek, Małgorzata, Wydra, Karolina, Nowak, Ewa, Górny, Magdalena, Filip, Małgorzata, Włodek, Lidia, Lorenc-Koci, Elżbieta

“…The role of cocaine in modulating the metabolism of sulfur-containing compounds in the peripheral tissues is poorly understood. In the present study we…”
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