Search Results - "Ma, Zhengcai"

Fine tuning the LightOn light-switchable transgene expression system by Ma, Zhengcai, Du, Zengmin, Chen, Xianjun, Wang, Xue, Yang, Yi

“…•The performance of LightOn system can be fine-tuned by modifying its components.•Promoter segments of target gene affect induction efficiency and leak…”
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Cyberpharmacology uncover the mechanism of the total Rhizoma Coptidis extracts ameliorate chronic atrophic gastritis by Ma, Zhengcai, Chen, Xiantao, Xiong, Mengyuan, Wang, Hongmei, Sun, Chunyong, Tang, Wanyu, Li, Juan, Li, Xiaoduo, Ma, Hang, Ye, Xiaoli

“…Characterized by inflammation of the gastric mucosa, atrophy of gastric gland cells, and intestinal metaplasia, Chronic Atrophic Gastritis (CAG) is a…”
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Palmatine ameliorates N‐methyl‐N'‐nitrosoguanidine‐induced chronic atrophic gastritis through the STAT1/CXCL10 axis by Zhou, Yuan, Wang, Qiaojiao, Tang, Wanyu, Ma, Zhengcai, Yang, Zhipeng, Li, Xuegang, Chen, Wanqun, Ma, Hang, Ye, Xiaoli

“…Chronic atrophic gastritis (CAG) is a prevalent preneoplastic condition of the stomach. Palmatine (PAL), an isoquinoline alkaloid isolated from Rhizoma…”
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An extraordinary stringent and sensitive light-switchable gene expression system for bacterial cells by Chen, Xianjun, Liu, Renmei, Ma, Zhengcai, Xu, Xiaopei, Zhang, Haoqian, Xu, Jianhe, Ouyang, Qi, Yang, Yi

“…Dear Editor, Light-switchable gene expression systems provide transient, non-invasive and reversible means to control biological processes with high tunability…”
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Coptisine inhibits Helicobacter pylori and reduces the expression of CagA to alleviate host inflammation in vitro and in vivo by Tang, Qin, Ma, Zhengcai, Tang, Xiang, Liu, Yan, Wu, Huimin, Peng, Yu, Jiao, Baihua, Wang, Rui, Ye, Xiaoli, Ma, Hang, Li, Xuegang

“…Helicobacter pylori (H. pylori) is a major pathogen colonized in the human stomach and is implicated in gastritis, peptic ulcer, and gastric carcinoma…”
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Epiberberine induced p53/p21-dependent G2/M cell cycle arrest and cell apoptosis in gastric cancer cells by activating γ-aminobutyric acid receptor- β3 by Li, Mengmeng, Yang, Jiaye, Li, Juan, Zhou, Yuan, Li, Xiaoduo, Ma, Zhengcai, Li, Xuegang, Ma, Hang, Ye, Xiaoli

“…Epiberberine (EPI) is one of the most important bioalkaloid found in the rhizome of Coptis chinensis, which has been observed to exhibit pharmaceutical effects…”
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Integrating transcriptomics and network pharmacology to reveal the mechanisms of total Rhizoma Coptidis alkaloids against nonalcoholic steatohepatitis by Li, Juan, Ma, Zhengcai, Yang, Zhipeng, Yang, Maochun, Li, Changsheng, Li, Mengmeng, Li, Xiaoduo, Chen, Xiantao, Ma, Hang, Chen, Wanqun, Ye, Xiaoli, Li, Xuegang

“…Non-alcoholic steatohepatitis (NASH) has emerged as a major cause of cirrhosis and hepatocellular carcinoma, posing a significant threat to public health…”
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Palmatine attenuates MYH9 mediated nuclear localization of AURKA to induce G2/M phase arrest in colorectal cancer cells by Tang, Wanyu, Li, Jingwei, Zhou, Yuan, Li, Juan, Ma, Zhengcai, Li, Xiaoduo, Wang, Hongmei, Xiong, Mengyuan, Chen, Xiantao, Li, Xuegang, Chen, Wanqun, Ma, Hang, Ye, Xiaoli

“…[Display omitted] •PAL decreased the nuclear localization of AURKA.•PAL repressed interaction of AURKA and MYH9 promoting nuclear AURKA level decreasing.•MYH9…”
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8-octyl berberine combats Staphylococcus aureus by preventing peptidoglycan synthesis by Li, Xiaoduo, Ma, Zhengcai, Tang, Qin, Gui, Zhenwei, Zhang, Biao, Sun, Guang, Li, Jingwei, Li, Juan, Li, Mengmeng, Li, Xuegang, Ma, Hang, Ye, Xiaoli

“…•We synthesized a new compound (8-Octyl Berberine, OBBR) that derived from berberine in our laboratory at first.•OBBR is an effective antibacterial agent with…”
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Coptisine-mediated downregulation of E2F7 induces G2/M phase arrest in hepatocellular carcinoma cells through inhibition of E2F4/NFYA/NFYB transcription factors by Wang, Hongmei, Ma, Zhengcai, Xu, Minmin, Xiong, Mengyuan, Chen, Xiantao, Zhou, Yuan, Tang, Wanyu, Li, Xuegang, Chen, Wanqun, Ma, Hang, Ye, Xiaoli

“…Coptisine (COP) has been shown to exhibit a wide range of anticancer properties, including in hepatocellular carcinoma (HCC). Nevertheless, the precise…”
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Berberine promotes IGF2BP3 ubiquitination by TRIM21 to induce G1/S phase arrest in colorectal cancer cells by Gui, Zhenwei, Li, Jingwei, Li, Juan, Li, Xiaoduo, Chen, Lihong, Ma, Zhengcai, Tang, Xiang, Gong, Xiaobao, Chai, Xue, Lu, Fangfang, Li, Mengmeng, Ma, Hang, Li, Xuegang, Ye, Xiaoli

“…The increasing incidence of colorectal cancer (CRC) has become a major global public health burden. The natural drug Berberine (BBR) has shown potential in…”
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Spatiotemporal control of gene expression in mammalian cells and in mice using the LightOn system by Chen, Xianjun, Wang, Xue, Du, Zengmin, Ma, Zhengcai, Yang, Yi

“…A light-switchable transgene system could be a powerful optogenetic tool for the precise manipulation of spatiotemporal gene expression in multicellular…”
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