Search Results - "Ma, Yuheng"
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Small Molecule Inhibitors against the Bacterial Pathogen Brucella
Published in Current medicinal chemistry (01-01-2024)“…Brucellosis remains one of the major zoonotic diseases worldwide. As a causative agent of brucellosis, it has many ways to evade recognition by the immune…”
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Fragment-based Drug Discovery Strategy and its Application to the Design of SARS-CoV-2 Main Protease Inhibitor
Published in Current medicinal chemistry (01-01-2024)“…Severe Acute Respiratory Syndrome Coronavirus Type 2 (SARS-CoV-2) emerged at the end of 2019, causing a highly infectious and pathogenic disease known as 2019…”
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Highly Stable, Mechanically Enhanced, and Easy-to-Collect Sodium Alginate/NZVI-rGO Gel Beads for Efficient Removal of Cr(VI)
Published in Polymers (01-09-2023)“…Nanoscale zero-valent iron (NZVI) is a material that is extensively applied for water pollution treatment, but its poor dispersibility, easy oxidation, and…”
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Metabolic and Process Engineering of Clostridium beijerinckii for Butyl Acetate Production in One Step
Published in Journal of agricultural and food chemistry (02-09-2020)“…n-Butyl acetate is an important food additive commonly produced via concentrated sulfuric acid catalysis or immobilized lipase catalysis of butanol and acetic…”
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Photoelectrochemical detection of microRNAs based on target-triggered self-assembly of energy band position–matched CdS QDs and C3N4 nanosheets
Published in Mikrochimica acta (1966) (01-02-2022)“…An ultrasensitive photochemical biosensor based on the target miRNA-triggered catalytic hairpin assembly (CHA) reaction between Au nanoparticles (AuNPs)/C 3 N…”
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Dynamic Response of Curved Tunnels under Vertical Incidence of Transversal SV Waves
Published in Shock and vibration (25-04-2023)“…Long tunnels often have curved sections when alignment designs are influenced by topography, adverse geology, and environmental factors. When the transversal…”
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Eco-friendly strategy for synthesizing europium-complex-based hybrid materials using bifunctional hydroxyapatite
Published in Materials & design (01-09-2023)“…[Display omitted] •Eu-complex-based hybrids were prepared using hydroxyapatite as both eco-friendly alkaline reagent and matrix.•The quantum yield and lifetime…”
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One-Step Synthesis of Water-Soluble Silver Sulfide Quantum Dots and Their Application to Bioimaging
Published in ACS omega (09-03-2021)“…This work reports a simple water-phase microwave method for the synthesis of water-soluble red emission Ag2S quantum dots at low temperatures without the need…”
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Optimizing drug combination and mechanism analysis based on risk pathway crosstalk in pan cancer
Published in Scientific data (16-01-2024)“…Combination therapy can greatly improve the efficacy of cancer treatment, so identifying the most effective drug combination and interaction can accelerate the…”
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In vitro dual-target activities and in vivo antidiabetic effect of 3-hydroxy-N-(p-hydroxy-phenethyl) phthalimide in high-fat diet and streptozotocin-induced diabetic golden hamsters
Published in Medicinal chemistry research (01-11-2020)“…The 3-hydroxy- N -( p -hydroxy-phenethyl) phthalimide (HNHP), which showed in vitro peroxisome proliferator-activated receptor-γ (PPAR-γ) activation and in…”
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11
QingXiaoWuWei decoction alleviates methicillin-resistant Staphylococcus aureus -induced pneumonia in mice by regulating metabolic remodeling and macrophage gene expression network via the microbiota-short-chain fatty acids axis
Published in Microbiology spectrum (12-12-2023)“…Methicillin-resistant (MRSA) colonizes the upper respiratory airways and is resistant to antibiotics. MRSA is a frequently acquired infection in hospital and…”
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Design, Synthesis, Biological Evaluation, and Structure−Activity Relationship (SAR) Discussion of Dipeptidyl Boronate Proteasome Inhibitors, Part I: Comprehensive Understanding of the SAR of α-Amino Acid Boronates
Published in Journal of medicinal chemistry (23-07-2009)“…New series of dipeptidyl boronate inhibitors of 20S proteasome were designed and synthesized. The comprehensive understanding of the SAR was obtained by…”
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An efficient synthesis of ( R)- and ( S)-baclofen via desymmetrization
Published in Tetrahedron letters (11-11-2009)“…A short and highly enantioselective synthesis of both enantiomers of GABA agonist baclofen in four steps with total yields of 32.8% [for ( S)-isomer] and 35.1%…”
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Synthesis and SAR study of novel peptide aldehydes as inhibitors of 20S proteasome
Published in Molecules (Basel, Switzerland) (05-09-2011)“…Based on the analysis of the crystal structure of MG101 (1) and 20S proteasomes, a new series of peptide aldehyde derivatives were designed and synthesized…”
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Synthesis of salinosporamide A and its analogs as 20S proteasome inhibitors and SAR summarization
Published in Current topics in medicinal chemistry (01-12-2011)“…Salinosporamide A (4), a secondary metabolite of the marine actinomycete Salinispora tropica, is a potent inhibitor of 20S proteasome that is currently in…”
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Research progress of plasma melting technology in radioactive waste treatment of nuclear power plants
Published in Annals of nuclear energy (01-04-2024)Get full text
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In-depth understanding of transport behavior of sulfided nano zerovalent iron/reduced graphene oxide@guar gum slurry: Stability and mobility
Published in Journal of environmental sciences (China) (01-10-2024)“…•S-NZVI/rGO@GG slurry showed excellent stability and mobility performance.•Higher GG concentration, pH, and low ionic strength are beneficial to improve the…”
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Comprehensive understanding of adsorption and reduction on 2,4-DCP and Cr(VI) removal process by NZVI-rGO: Performance and mechanism
Published in Journal of water process engineering (01-02-2023)“…In this study, nano zero-valent iron-reduced graphene oxide (NZVI-rGO) was successfully synthesized and applied for 2,4-DCP and Cr (VI) removal…”
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Dual-mode corroborative detection of miRNA-21 based on catalytic hairpin assembly reaction and oxygen reduction reaction combined strategy for the signal amplification
Published in Sensors and actuators. B, Chemical (01-08-2022)“…Here, we first combined the catalytic hairpin assembly (CHA) reaction and oxygen reduction reaction (ORR) to amplify the electrochemical signal for the…”
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An N-terminal heptad repeat trimer-based peptide fusion inhibitor exhibits potent anti-H1N1 activity
Published in Bioorganic & medicinal chemistry (01-09-2024)“…[Display omitted] •First peptide-based fusion inhibitor acting with the CHR region of H1N1 HA2 to block nature 6-HB formation.•Validation of the feasibility…”
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