Search Results - "Ma, Yinling"
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Development of UPLC-MS/MS Method to Study the Pharmacokinetic Interaction between Sorafenib and Dapagliflozin in Rats
Published in Molecules (Basel, Switzerland) (21-09-2022)“…Sorafenib (SOR), an inhibitor of multiple kinases, is a classic targeted drug for advanced hepatocellular carcinoma (HCC) which often coexists with type 2…”
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Pharmacokinetic Interactions between Canagliflozin and Sorafenib or Lenvatinib in Rats
Published in Molecules (Basel, Switzerland) (24-08-2022)“…Hepatocellular carcinoma (HCC) and type 2 diabetes mellitus (T2DM) are common clinical conditions, and T2DM is an independent risk factor for HCC. Sorafenib…”
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Determination of Osimertinib, Aumolertinib, and Furmonertinib in Human Plasma for Therapeutic Drug Monitoring by UPLC-MS/MS
Published in Molecules (Basel, Switzerland) (13-07-2022)“…The third-generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), osimertinib, aumolertinib, and furmonertinib represent a new…”
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DNA methyltransferase 1 inhibits microRNA-497 and elevates GPRC5A expression to promote chemotherapy resistance and metastasis in breast cancer
Published in Cancer cell international (07-03-2022)“…Abnormal DNA methylation of tumor suppressor gene promoter has been found in breast cancer. Therefore, the current study set out to explore how DNA…”
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A Complete Study of Farrerol Metabolites Produced in Vivo and in Vitro
Published in Molecules (Basel, Switzerland) (24-09-2019)“…Although farrerol, a characteristically bioactive constituent of L., exhibits extensive biological and pharmacological activities (e.g., anti-oxidant,…”
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QiShenYiQi pills, a Chinese patent medicine, increase bioavailability of atorvastatin by inhibiting Mrp2 expression in rats
Published in Pharmaceutical biology (01-12-2022)“…Atorvastatin (ATV) and QiShenYiQi pills (QSYQ), a Chinese patent medicine, are often co-prescribed to Chinese cardiovascular patients. The effects of QSYQ on…”
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Analysis of Galangin and Its In Vitro/In Vivo Metabolites via Ultra-High-Performance Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry
Published in Metabolites (28-10-2022)“…Galangin, a naturally available flavonoid, induces a variety of pharmacological activities and biological effects via several mechanisms. However, in vivo…”
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Qualitative and Quantitative Determination of Oligonucleotides by Non-Gel Capillary Electrophoresis
Published in Chromatographia (01-03-2011)“…A novel simple non-gel capillary electrophoresis (NGCE) method was developed for the qualitative and quantitative determination of oligonucleotides (ODNs)…”
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A Systematic Study of the Metabolites of Dietary Acacetin in Vivo and in Vitro Based on UHPLC-Q-TOF-MS/MS Analysis
Published in Journal of agricultural and food chemistry (15-05-2019)“…Acacetin, a dietary component, is abundant in acacia honey and has superior anticancer activities. To date, no research on the metabolism of acacetin has been…”
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Practicality of non-invasive glucagon-loaded dissolving microneedle for life-saving treatment of severe hypoglycemia in a diabetic rat model
Published in International journal of pharmaceutics (25-09-2023)“…(A)Preparation process of dissolved microneedles; (B) Establishment of experimental animal model; (C) Mechanism of action of drug-loaded dissolved microneedles…”
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Quantitative determination of characteristic components from compound of Lysionotus pauciflorus Maxim. by LC–MS/MS and its application to a pharmacokinetic study
Published in Journal of pharmaceutical and biomedical analysis (05-01-2020)“…•Tuberculosis of cervical lymph nodes is called scrofula in Traditional Chinese Medicine. Clinical manifestation is that unilateral or bilateral neck can have…”
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A one-stop integrated natural antimicrobial microneedles with anti-inflammatory, pro-angiogenic and long-term moisturizing properties to accelerate diabetic wound healing
Published in European journal of pharmaceutics and biopharmaceutics (01-10-2024)“…[Display omitted] Diabetic ulcers present a formidable obstacle in diabetes management, typically leading to high mortality and amputation rates. To overcome…”
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Comprehensive Study of the in Vivo and in Vitro Metabolism of Dietary Isoflavone Biochanin A Based on UHPLC-Q-TOF-MS/MS
Published in Journal of agricultural and food chemistry (13-11-2019)“…Biochanin A is a dietary isoflavone with multiple biological functions. Owing to a lack of comprehensive studies of biochanin A metabolism, this study was…”
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A comprehensive study of the metabolism of flavonoid oroxin B in vivo and in vitro by UHPLC-Q-TOF-MS/MS
Published in Journal of pharmaceutical and biomedical analysis (15-04-2021)“…[Display omitted] •The metabolism of oroxin B, a major flavonoid from Oroxylum indicum (L.) Vent, was comprehensively investigated in rats.•UHPLC-Q-TOF-MS/MS…”
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Effects of voriconazole and fluconazole on the pharmacokinetics of almonertinib in rats by UPLC–MS/MS
Published in Biomedical chromatography (01-01-2023)“…Almonertinib was included in the first‐line treatment of non‐small cell lung cancer with EGFR T790M mutations by the Chinese Society of Clinical Oncology in…”
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Influence of schisantherin A on the pharmacokinetics of lenvatinib in rats and its potential mechanism
Published in Journal of gastrointestinal oncology (01-04-2022)“…Lenvatinib (LEN) is approved as first-line therapy for advanced hepatocellular carcinoma (HCC). Schisantherin A (STA) can exert hepatoprotective and anti-tumor…”
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Proton pump inhibitor-induced exfoliative dermatitis: A case report
Published in Experimental and therapeutic medicine (01-02-2016)“…A 74-year-old female patient was admitted to hospital following a road accident with pains in the chest, abdomen, waist, back, nose, left wrist and lower…”
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