Search Results - "Ma, Yaojia"
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Alteration of the tumor microenvironment by pharmacological inhibition of EZH2 in hepatocellular carcinoma
Published in International immunopharmacology (01-05-2023)“…•Pharmacological inhibition of EZH2 results in increasing MDSCs and attenuating CD8+ T cells in the tumor microenvironment of HCC.•Depletion of MDSCs by…”
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Antiviral Compounds Screening Targeting HBx Protein of the Hepatitis B Virus
Published in International journal of molecular sciences (01-10-2022)“…A functional cure of hepatitis B virus (HBV) infection or HB antigen loss is rarely achieved by nucleos(t)ide analogs which target viral polymerase. HBx…”
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Successful Identification of a Novel Therapeutic Compound for Hepatocellular Carcinoma Through Screening of ADAM9 Inhibitors
Published in Anticancer research (01-03-2023)“…MHC-class I-related chain A (MICA) functions as a ligand for natural killer group D, an activating receptor on natural killer (NK) cells, and its expression…”
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Serum Angiopoietin 2 acts as a diagnostic and prognostic biomarker in hepatocellular carcinoma
Published in Journal of Cancer (01-01-2021)“…Hepatocellular carcinoma (HCC) is typically accompanied by abundant arterial blood flow. Although angiogenic growth factors such as Angiopoietin 2 (Ang2) play…”
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Acquisition of mesenchymal-like phenotypes and overproduction of angiogenic factors in lenvatinib-resistant hepatocellular carcinoma cells
Published in Biochemical and biophysical research communications (16-04-2021)“…Lenvatinib is one of the first-line drugs for patients with advanced hepatocellular carcinoma (HCC) and widely used around the world. However, the mechanisms…”
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A diet-induced murine model for non-alcoholic fatty liver disease with obesity and insulin resistance that rapidly develops steatohepatitis and fibrosis
Published in Laboratory investigation (01-10-2022)“…Non-alcoholic fatty liver disease (NAFLD) has become the leading cause of chronic liver disease worldwide. Patients with NAFLD often suffer steatohepatitis,…”
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Miglustat, a glucosylceramide synthase inhibitor, mitigates liver fibrosis through TGF-β/Smad pathway suppression in hepatic stellate cells
Published in Biochemical and biophysical research communications (29-01-2023)“…Transforming growth factor (TGF)-β/Smad pathway is implicated in the pathogenesis of liver fibrosis, a condition characterized by excessive deposition of…”
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Re-analysis of hepatitis B virus integration sites reveals potential new loci associated with oncogenesis in hepatocellular carcinoma
Published in World journal of virology (25-06-2023)“…Hepatitis B virus (HBV) is a major cause of hepatocellular carcinoma (HCC). HBV DNA can get integrated into the hepatocyte genome to promote carcinogenesis…”
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Effect of Atezolizumab plus Bevacizumab in Patients with Hepatocellular Carcinoma Harboring CTNNB1 Mutation in Early Clinical Experience
Published in Journal of Cancer (2022)“…Atezolizumab plus bevacizumab (ATZ/BV) treatment is a combined immunotherapy consisting of immune checkpoint inhibitor (ICI) and anti-vascular endothelial…”
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A diet-induced murine model for non-alcoholic fatty liver disease with obesity and insulin resistance that rapidly develops steatohepatitis and fibrosis
Published in Laboratory investigation (01-10-2022)“…Non-alcoholic fatty liver disease (NAFLD) has become the leading cause of chronic liver disease worldwide. Patients with NAFLD often suffer steatohepatitis,…”
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EP1182: PATHOGENESIS OF PRIMARY SCLEROSING CHOLANGITIS BY BILE PROTEOME ANALYSIS USING HIGH-PRECISION MASS SPECTROMETRY
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2022)Get full text
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