Search Results - "Ma, Xiaosheng"
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Preparation of antibacterial and osteoconductive 3D-printed PLGA/Cu(I)@ZIF-8 nanocomposite scaffolds for infected bone repair
Published in Journal of nanobiotechnology (27-02-2020)“…The repair of large bone defects is a great challenge in clinical practice. In this study, copper-loaded-ZIF-8 nanoparticles and poly (lactide-co-glycolide)…”
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TLR4 promotes microglial pyroptosis via lncRNA-F630028O10Rik by activating PI3K/AKT pathway after spinal cord injury
Published in Cell death & disease (10-08-2020)“…Neuroinflammation plays a crucial role in the secondary phase of spinal cord injury (SCI), and is initiated following the activation of toll-like receptor 4…”
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Exosomes from Long Noncoding RNA-Gm37494-ADSCs Repair Spinal Cord Injury via Shifting Microglial M1/M2 Polarization
Published in Inflammation (01-08-2020)“…Spinal cord injury (SCI) may lead to severe motor and sensory dysfunction, causing high mortality and disability rates. Adipose tissue-derived mesenchymal…”
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Ecto-5'-nucleotidase (CD73) attenuates inflammation after spinal cord injury by promoting macrophages/microglia M2 polarization in mice
Published in Journal of neuroinflammation (22-05-2018)“…Immune activation, specifically activation of macrophages and resident microglia, leading to inflammation is a key component in the progression of spinal cord…”
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MSC-Derived Exosomes Protect Vertebral Endplate Chondrocytes against Apoptosis and Calcification via the miR-31-5p/ATF6 Axis
Published in Molecular therapy. Nucleic acids (04-12-2020)“…Apoptosis and calcification of endplate chondrocytes (EPCs) can exacerbate intervertebral disc degeneration (IVDD). Mesenchymal stem cell-derived exosomes…”
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Comparative analysis of the biomechanics of anterior cervical discectomy and fusion with multiple segmental plates fixation versus single multilevel plate fixation: a finite element study
Published in BMC musculoskeletal disorders (07-09-2022)“…Abstract Background This study aimed to compare the biomechanical differences between anterior cervical discectomy and fusion (ACDF) with multiple-level…”
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Comparison of Intraoperative Neuromonitoring Outcome in Treating Thoracic Ossification of the Ligamentum Flavum Through En Bloc Versus Piecemeal Laminectomy
Published in Spine (Philadelphia, Pa. 1976) (01-09-2021)“…Study Design. A retrospective cohort analysis. Objective. The aim of this study was to investigate the impact of piecemeal versus en bloc laminectomies on…”
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Establishment of a clinician-led guideline on the diagnosis and treatment of Hirayama disease using a modified Delphi technique
Published in Clinical neurophysiology (01-06-2020)“…•A modified 3-round Delphi survey resulted in a clinician-led guideline in Hirayama disease (HD).•This is the first time to establish a clinician-led guideline…”
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Prognostic nomograms for predicting overall and cancer-specific survival of high-grade osteosarcoma patients
Published in Journal of bone oncology (01-11-2018)“…The present study aimed to develop nomograms estimating survival for patients with high-grade osteosarcoma. 1990 patients with high-grade osteosarcoma between…”
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Chondrocyte-targeted exosome-mediated delivery of Nrf2 alleviates cartilaginous endplate degeneration by modulating mitochondrial fission
Published in Journal of nanobiotechnology (24-05-2024)“…Cartilaginous endplate (CEP) degeneration, which is an important contributor to intervertebral disc degeneration (IVDD), is characterized by chondrocyte death…”
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Dual drugs release from nanoporously bioactive coating on polyetheretherketone for enhancement of antibacterial activity, rBMSCs responses and osseointegration
Published in Materials & design (01-03-2020)“…A bioactive coating of nanoporous magnesium calcium silicate (n-MCS) on polyetheretherketone (ncPK) surface was prepared, and dual drugs of genistein (GS) and…”
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Update on the Pathogenesis, Clinical Diagnosis, and Treatment of Hirayama Disease
Published in Frontiers in neurology (01-02-2022)“…Hirayama disease (HD) is characterized by the juvenile onset of unilateral or asymmetric weakness and amyotrophy of the hand and ulnar forearm and is most…”
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Engineered exosomes enriched in netrin-1 modRNA promote axonal growth in spinal cord injury by attenuating inflammation and pyroptosis
Published in Biomaterials research (17-01-2023)“…Spinal cord injury (SCI) brings a heavy burden to individuals and society, and there is no effective treatment at present. Exosomes (EX) are cell secreted…”
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Factors Affecting the Surgical Outcomes of Hirayama Disease: A Retrospective Analysis of Preoperative Magnetic Resonance Imaging Features of the Cervical Spine
Published in World neurosurgery (01-02-2019)“…We explored the factors affecting the surgical outcomes of Hirayama disease (HD). We enrolled 40 patients with a diagnosis of HD in the present study. Cervical…”
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A study of screw placement to obtain the optimal pull-out resistance of lumbar pedicle screws-analysis of Hounsfield units measurements based on computed tomography
Published in BMC musculoskeletal disorders (07-02-2022)“…The screw path of lumbar pedicle screws in the vertebral body has certain variability. It is not clear whether the screw paths in different directions can…”
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Low lumbar multifidus muscle status and bone mineral density are important risk factors for adjacent segment disease after lumbar fusion: a case–control study
Published in Journal of orthopaedic surgery and research (16-11-2022)“…Abstract Background The quantity and quality of the paraspinal muscles are important factors that lead to spinal diseases. However, the role of paraspinal…”
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How to reconstruct the lordosis of cervical spine in patients with Hirayama disease? A finite element analysis of biomechanical changes focusing on adjacent segments after anterior cervical discectomy and fusion
Published in Journal of orthopaedic surgery and research (16-02-2022)“…To compare the biomechanical changes of adjacent segments between patients with Hirayama disease and non-pathological people after anterior cervical discectomy…”
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Establishment of the Lunar Phase Morphological Classification for Cervical Spinal Canal
Published in Asian spine journal (01-02-2024)“…Retrospective clinical trial. To establish a morphological classification of the cervical spinal canal using its parameters. Cervical spine computed tomography…”
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Do patients with Hirayama disease require surgical treatment? A review of the literature
Published in Intractable & Rare Diseases Research (01-11-2022)“…The main clinic characteristic of Hirayama disease (HD) is atrophy of the distal muscles in the upper limbs. Recently, an increasing number of HD cases have…”
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The evaluation on neural status of cervical spinal cord in normal and Hirayama disease using diffusion tensor imaging
Published in European spine journal (01-08-2019)“…Purpose To explore the changes in diffusion tensor imaging (DTI) parameters in cervical spinal cord in Hirayama disease (HD) patients and healthy volunteers…”
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