Search Results - "Ma, Xianxiong"
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CircGSK3B promotes RORA expression and suppresses gastric cancer progression through the prevention of EZH2 trans-inhibition
Published in Journal of experimental & clinical cancer research (19-10-2021)“…Circular RNAs (circRNAs) are a class of non-coding RNA that play critical roles in the development and pathogenesis of various cancers. The circRNA circGSK3B…”
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4-OI Attenuates Carbon Tetrachloride-Induced Hepatic Injury via Regulating Oxidative Stress and the Inflammatory Response
Published in Frontiers in pharmacology (25-05-2021)“…The liver is an important metabolic organ, and acute liver injury (ALI) is potentially lethal. Itaconate, a metabolic intermediate from the tricarboxylic acid…”
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3
Targeting MUS81 promotes the anticancer effect of WEE1 inhibitor and immune checkpoint blocking combination therapy via activating cGAS/STING signaling in gastric cancer cells
Published in Journal of experimental & clinical cancer research (08-10-2021)“…Identification of genomic biomarkers to predict the anticancer effects of indicated drugs is considered a promising strategy for the development of precision…”
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4
Human gastric cancer progression and stabilization of ATG2B through RNF5 binding facilitated by autophagy-associated CircDHX8
Published in Cell death & disease (12-06-2024)“…The role of circDHX8 in the interplay between autophagy and gastric cancer (GC) progression remains unclear. In this study, we investigated the mechanism…”
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A methylomics-correlated nomogram predicts the recurrence free survival risk of kidney renal clear cell carcinoma
Published in Mathematical biosciences and engineering : MBE (01-01-2021)“…Various studies have suggested that the DNA methylation signatures were promising to identify novel hallmarks for predicting prognosis of cancer. However, few…”
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Prognostic significance of microRNA-101 in solid tumor: A meta-analysis
Published in PloS one (25-07-2017)“…MicroRNA-101 has been reported as an important factor in carcinogenesis of several malignant tumors. However, its actual role in prognosis among solid…”
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LINC00571 drives tricarboxylic acid cycle metabolism in triple-negative breast cancer through HNRNPK/ILF2/IDH2 axis
Published in Journal of experimental & clinical cancer research (18-01-2024)“…Triple-negative breast cancer is a complex breast malignancy subtype characterized by poor prognosis. The pursuit of effective therapeutic approaches for this…”
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Transcription Factor Profiling to Predict Recurrence-Free Survival in Breast Cancer: Development and Validation of a Nomogram to Optimize Clinical Management
Published in Frontiers in genetics (24-04-2020)“…Breast cancer (BC) is the most frequently diagnosed cancer and the leading cause of cancer-related death in young women. Several prognostic and predictive…”
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HDAC is indispensable for IFN-γ-induced B7-H1 expression in gastric cancer
Published in Clinical epigenetics (11-12-2018)“…B7 homolog 1 (B7-H1) overexpression on tumor cells is an important mechanism of immune evasion in gastric cancer (GC). Elucidation of the regulation of B7-H1…”
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10
Clinicopathological and Prognostic Value of Plasma CD24 Level in Hepatocellular Carcinoma
Published in Journal of investigative surgery (02-07-2020)“…Purpose: CD24 is overexpressed in hepatocellular carcinoma (HCC) tumor tissues and in the highly metastatic HCC cell lines. However, plasma CD24 level in HCC…”
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A methylomics‐associated nomogram predicts recurrence‐free survival of thyroid papillary carcinoma
Published in Cancer medicine (Malden, MA) (01-10-2020)“…Background Thyroid papillary carcinoma (TPC) is the most common type of thyroid cancer (TC). The prognosis of TPC patients with tumor‐cell metastasis is poor…”
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Centrosomal protein 120 promotes centrosome amplification and gastric cancer progression via USP54-mediated deubiquitination of PLK4
Published in iScience (20-01-2023)“…Centrosomal protein 120 (CEP120) is a 120 kDa centrosome protein that plays an important role in centrosome replication. Overexpression of CEP120 can lead to…”
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Classification of Estrogen Receptor-Positive Breast Cancer Based on Immunogenomic Profiling and Validation at Single-Cell Resolution
Published in Frontiers in cell and developmental biology (21-09-2021)“…Background: The aim of this paper was to identify an immunotherapy-sensitive subtype for estrogen receptor-positive breast cancer (ER+ BC) patients by…”
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Transcription factor SP1-induced microRNA-146b-3p facilitates the progression and metastasis of colorectal cancer via regulating FAM107A
Published in Life sciences (1973) (15-07-2021)“…Recent studies have provided compelling evidence regarding the association of microRNAs (miRNAs) with the progression and development of tumors. Among the…”
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The circMYBL2-encoded p185 protein suppresses colorectal cancer progression by inhibiting serine biosynthesis
Published in Cancer research (Chicago, Ill.) (02-07-2024)“…Circular RNAs (circRNAs) are a class of covalently closed single-stranded loop RNAs that have been implicated to play a functional role in almost all types of…”
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DNA methylation profiling to predict recurrence risk in stage Ι lung adenocarcinoma: Development and validation of a nomogram to clinical management
Published in Journal of cellular and molecular medicine (01-07-2020)“…Increasing evidence suggested DNA methylation may serve as potential prognostic biomarkers; however, few related DNA methylation signatures have been…”
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4-Octyl itaconate regulates immune balance by activating Nrf2 and negatively regulating PD-L1 in a mouse model of sepsis
Published in International journal of biological sciences (2022)“…Sepsis is a major global health challenge with high mortality rates and no effective treatment. Recent studies have suggested that sepsis may be associated…”
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Targeting BCL6 in gastrointestinal stromal tumor promotes p53-mediated apoptosis to enhance the antitumor activity of imatinib
Published in Cancer research (Chicago, Ill.) (01-11-2023)“…Imatinib mesylate (IM) has revolutionized the treatment of gastrointestinal stromal tumor (GIST). However, most patients inevitably acquire IM resistance…”
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Identification of the hub genes and transcription factor‑miRNA axes involved in Helicobacter pylori ‑associated gastric cancer
Published in Oncology letters (01-03-2022)“…It has been previously reported that transcription factor-microRNA (TF-miRNA) axes play a significant role in the carcinogenesis of several types of malignant…”
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Identification of a 5‑microRNA signature and hub miRNA‑mRNA interactions associated with pancreatic cancer
Published in Oncology reports (01-01-2019)“…miRNA‑gene axes have been reported to serve an important role in the carcinogenesis of pancreatic cancer (PC). The aim of the present study was to…”
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