Search Results - "Ma, Terry K. W."
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Renin–angiotensin–aldosterone system blockade for cardiovascular diseases: current status
Published in British journal of pharmacology (01-07-2010)“…Activation of the renin–angiotensin–aldosterone system (RAAS) results in vasoconstriction, muscular (vascular and cardiac) hypertrophy and fibrosis…”
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Variability in response to clopidogrel: how important are pharmacogenetics and drug interactions?
Published in British journal of clinical pharmacology (01-10-2011)“…Clopidogrel is a pro‐drug which is converted to an active metabolite that selectively blocks ADP‐dependent platelet activation and aggregation. The main enzyme…”
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Causes of Mortality in Patients With Peptic Ulcer Bleeding: A Prospective Cohort Study of 10,428 Cases
Published in The American journal of gastroenterology (01-01-2010)“…Despite advances in endoscopic and pharmacological treatment for peptic ulcer bleeding (PUB), mortality remains at 5-10% worldwide. Our aim was to investigate…”
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Endoscopy for upper gastrointestinal bleeding: how urgent is it?
Published in Nature reviews. Gastroenterology & hepatology (01-08-2009)“…The optimal timing of endoscopy after presentation with upper gastrointestinal bleeding is a matter for debate. Tsoi and colleagues examine the findings of…”
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Alternatives to chronic warfarin therapy for the prevention of stroke in patients with atrial fibrillation
Published in International journal of cardiology (01-07-2011)“…Abstract Atrial fibrillation (AF) is associated with a fivefold increased risk for stroke due to thromboembolic events. Warfarin remains the standard medical…”
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Dabigatran etexilate versus warfarin as the oral anticoagulant of choice? A review of clinical data
Published in Pharmacology & therapeutics (Oxford) (01-02-2011)“…For many years, warfarin was the only effective oral anticoagulant to prevent and treat thromboembolism. Nevertheless, its clinical use is limited by a narrow…”
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Impact of genetic and acquired alteration in cytochrome P450 system on pharmacologic and clinical response to clopidogrel
Published in Pharmacology & therapeutics (Oxford) (01-02-2010)“…Dual antiplatelet therapy with aspirin and clopidogrel has been shown to reduce subsequent cardiac events in patients with acute coronary syndrome or coronary…”
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