Search Results - "Ma, Stephen"
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Advanced maturation of human cardiac tissue grown from pluripotent stem cells
Published in Nature (London) (01-04-2018)“…Cardiac tissues generated from human induced pluripotent stem cells (iPSCs) can serve as platforms for patient-specific studies of physiology and disease1-6…”
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Engineering of human cardiac muscle electromechanically matured to an adult-like phenotype
Published in Nature protocols (01-10-2019)“…Author Manuscript The application of tissue-engineering approaches to human induced pluripotent stem (hiPS) cells enables the development of physiologically…”
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Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis
Published in Cell (31-01-2013)“…In stressed cells, apoptosis ensues when Bcl-2 family members Bax or Bak oligomerize and permeabilize the mitochondrial outer membrane. Certain BH3-only…”
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The promises and limitations of artificial intelligence for quality improvement, patient safety, and research in hospital medicine
Published in Journal of hospital medicine (15-05-2024)Get full text
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Laboratory validation and clinical utility of next-generation sequencing-based IGH/TCR clonality testing for the monitoring of measurable residual disease in acute lymphoblastic leukaemia: real-world experience at Austin Pathology
Published in Pathology (01-12-2024)“…Measurable residual disease (MRD) testing is an essential aspect of disease prognostication in acute lymphoblastic leukaemia (ALL) and informs clinical…”
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Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation
Published in Immunity (Cambridge, Mass.) (24-02-2012)“…Interleukin-1β (IL-1β) is a potent inflammatory cytokine that is usually cleaved and activated by inflammasome-associated caspase-1. To determine whether IL-1β…”
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Quantification of human neuromuscular function through optogenetics
Published in Theranostics (01-01-2019)“…The study of human neuromuscular diseases has traditionally been performed in animal models, due to the difficulty of performing studies in human subjects…”
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Tissue-Engineering for the Study of Cardiac Biomechanics
Published in Journal of biomechanical engineering (01-02-2016)“…The notion that both adaptive and maladaptive cardiac remodeling occurs in response to mechanical loading has informed recent progress in cardiac tissue…”
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Targeting repetitive laboratory testing with electronic health records-embedded predictive decision support: A pre-implementation study
Published in Clinical biochemistry (01-03-2023)“…Unnecessary laboratory testing contributes to patient morbidity and healthcare waste. Despite prior attempts at curbing such overutilization, there remains…”
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BAK α6 permits activation by BH3-only proteins and homooligomerization via the canonical hydrophobic groove
Published in Proceedings of the National Academy of Sciences - PNAS (18-07-2017)“…BAK and BAX are the essential effectors of apoptosis because without them a cell is resistant to most apoptotic stimuli. BAK and BAX undergo conformation…”
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Recommendations for Clinicians, Technologists, and Healthcare Organizations on the Use of Generative Artificial Intelligence in Medicine: A Position Statement from the Society of General Internal Medicine
Published in Journal of general internal medicine : JGIM (12-11-2024)“…Abstract Generative artificial intelligence (generative AI) is a new technology with potentially broad applications across important domains of healthcare, but…”
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Bioengineered optogenetic model of human neuromuscular junction
Published in Biomaterials (01-09-2021)“…Functional human tissues engineered from patient-specific induced pluripotent stem cells (hiPSCs) hold great promise for investigating the progression,…”
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Author Correction: Advanced maturation of human cardiac tissue grown from pluripotent stem cells
Published in Nature (London) (01-08-2019)“…An Amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Using Case Mix Index within Diagnosis-Related Groups to Evaluate Variation in Hospitalization Costs at a Large Academic Medical Center
Published in AMIA ... Annual Symposium proceedings (2023)“…In analyzing direct hospitalization cost and clinical data from an academic medical center, commonly used metrics such as diagnosis-related group (DRG) weight…”
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Antenatal course of referred monochorionic diamniotic twins complicated by selective intrauterine growth restriction (SIUGR) type III
Published in The journal of maternal-fetal & neonatal medicine (02-12-2021)“…To describe the antenatal course of selective intrauterine growth restriction (SIUGR) type III patients. Retrospective study of monochorionic diamniotic twins…”
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Cisplatin Increases Sensitivity to FGFR Inhibition in Patient-Derived Xenograft Models of Lung Squamous Cell Carcinoma
Published in Molecular cancer therapeutics (01-08-2017)“…Lung squamous cell carcinoma (SqCC) is a molecularly complex and genomically unstable disease. No targeted therapy is currently approved for lung SqCC,…”
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Artificial Intelligence-Generated Draft Replies to Patient Inbox Messages
Published in JAMA network open (20-03-2024)“…The emergence and promise of generative artificial intelligence (AI) represent a turning point for health care. Rigorous evaluation of generative AI deployment…”
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Data on location and retail price of a standard food basket in supermarkets across New York City
Published in Data in brief (01-06-2023)“…Previous work has suggested that the price of food sold at supermarkets may vary according to the socioeconomic characteristics of a neighborhood. Given the…”
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Photodirected Formation and Control of Wrinkles on a Thiol–ene Elastomer
Published in ACS macro letters (18-06-2013)“…Photopolymerization on a thiol–ene elastomer is a novel method to spatiotemporally control wrinkle formation gradients and complex patterns. Acrylate-rich…”
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Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway
Published in PLoS biology (26-01-2017)“…Lung squamous cell carcinoma (SqCC), the second most common subtype of lung cancer, is strongly associated with tobacco smoking and exhibits genomic…”
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