Search Results - "Ma, Peilin"

The protective role of DOT1L in UV-induced melanomagenesis by Zhu, Bo, Chen, Shuyang, Wang, Hongshen, Yin, Chengqian, Han, Changpeng, Peng, Cong, Liu, Zhaoqian, Wan, Lixin, Zhang, Xiaoyang, Zhang, Jie, Lian, Christine G., Ma, Peilin, Xu, Zhi-xiang, Prince, Sharon, Wang, Tao, Gao, Xiumei, Shi, Yujiang, Liu, Dali, Liu, Min, Wei, Wenyi, Wei, Zhi, Pan, Jingxuan, Wang, Yongjun, Xuan, Zhenyu, Hess, Jay, Hayward, Nicholas K., Goding, Colin R., Chen, Xiang, Zhou, Jun, Cui, Rutao

“…The DOT1L histone H3 lysine 79 (H3K79) methyltransferase plays an oncogenic role in MLL-rearranged leukemogenesis. Here, we demonstrate that, in contrast to…”
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A new target for differentiation therapy in AML by Ma, Peilin, Song, Weihua, Hess, Jay L

“…Despite major advances in under- standing the genetics and epigenetics of acute myelogenous leukemia, there is still a great need to develop more specific and…”
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HoxA9 binds and represses the Cebpa +8 kb enhancer by Peng, Lei, Guo, Hong, Ma, Peilin, Sun, Yuqing, Dennison, Lauren, Aplan, Peter D, Hess, Jay L, Friedman, Alan D

“…C/EBPα plays a key role in specifying myeloid lineage development. HoxA9 is expressed in myeloid progenitors, with its level diminishing during myeloid…”
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Rho Kinase Regulates the Survival and Transformation of Cells Bearing Oncogenic Forms of KIT, FLT3, and BCR-ABL by Mali, Raghuveer Singh, Ramdas, Baskar, Ma, Peilin, Shi, Jianjian, Munugalavadla, Veerendra, Sims, Emily, Wei, Lei, Vemula, Sasidhar, Nabinger, Sarah C., Goodwin, Charles B., Chan, Rebecca J., Traina, Fabiola, Visconte, Valeria, Tiu, Ramon V., Lewis, Timothy A., Stern, Andrew M., Wen, Qiang, Crispino, John D., Boswell, H. Scott, Kapur, Reuben

“…We show constitutive activation of Rho kinase (ROCK) in cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL, which is dependent on PI3K and Rho GTPase…”
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Pak and Rac GTPases promote oncogenic KIT-induced neoplasms by Martin, Holly, Mali, Raghuveer Singh, Ma, Peilin, Chatterjee, Anindya, Ramdas, Baskar, Sims, Emily, Munugalavadla, Veerendra, Ghosh, Joydeep, Mattingly, Ray R, Visconte, Valeria, Tiu, Ramon V, Vlaar, Cornelis P, Dharmawardhane, Suranganie, Kapur, Reuben

“…An acquired somatic mutation at codon 816 in the KIT receptor tyrosine kinase is associated with poor prognosis in patients with systemic mastocytosis and…”
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ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53 by Vemula, Sasidhar, Shi, Jianjian, Mali, Raghuveer Singh, Ma, Peilin, Liu, Yan, Hanneman, Philip, Koehler, Karl R., Hashino, Eri, Wei, Lei, Kapur, Reuben

“…Erythropoiesis is a dynamic, multistep process whereby hematopoietic stem cells differentiate toward a progressively committed erythroid lineage through…”
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Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT by Mali, Raghuveer Singh, Ma, Peilin, Zeng, Li-Fan, Martin, Holly, Ramdas, Baskar, He, Yantao, Sims, Emily, Nabinger, Sarah, Ghosh, Joydeep, Sharma, Namit, Munugalavadla, Veerendra, Chatterjee, Anindya, Li, Shuo, Sandusky, George, Craig, Andrew W., Bunting, Kevin D., Feng, Gen-Sheng, Chan, Rebecca J., Zhang, Zhong-Yin, Kapur, Reuben

“…Intracellular mechanism(s) that contribute to promiscuous signaling via oncogenic KIT in systemic mastocytosis and acute myelogenous leukemia are poorly…”
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p85β regulatory subunit of class IA PI3 kinase negatively regulates mast cell growth, maturation, and leukemogenesis by Krishnan, Subha, Mali, Raghuveer Singh, Ramdas, Baskar, Sims, Emily, Ma, Peilin, Ghosh, Joydeep, Munugalavadla, Veerendra, Hanneman, Philip, Beane, Joal D., Kapur, Reuben

“…We show that loss of p85α inhibits the growth and maturation of mast cells, whereas loss of p85β enhances this process. Whereas restoring the expression of…”
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The PI3K pathway drives the maturation of mast cells via microphthalmia transcription factor by Ma, Peilin, Mali, Raghuveer Singh, Munugalavadla, Veerendra, Krishnan, Subha, Ramdas, Baskar, Sims, Emily, Martin, Holly, Ghosh, Joydeep, Li, Shuo, Chan, Rebecca J., Krystal, Gerald, Craig, Andrew W., Takemoto, Clifford, Kapur, Reuben

“…Mast cell maturation is poorly understood. We show that enhanced PI3K activation results in accelerated maturation of mast cells by inducing the expression of…”
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Class I(A) PI3Kinase regulatory subunit, p85α, mediates mast cell development through regulation of growth and survival related genes by Krishnan, Subha, Mali, Raghuveer Singh, Koehler, Karl R, Vemula, Sasidhar, Chatterjee, Anindya, Ghosh, Joydeep, Ramdas, Baskar, Ma, Peilin, Hashino, Eri, Kapur, Reuben

“…Stem cell factor (SCF) mediated KIT receptor activation plays a pivotal role in mast cell growth, maturation and survival. However, the signaling events…”
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Balanced Interactions between Lyn, the p85α Regulatory Subunit of Class IA Phosphatidylinositol-3-Kinase, and SHIP Are Essential for Mast Cell Growth and Maturation by Ma, Peilin, Vemula, Sasidhar, Munugalavadla, Veerendra, Chen, Jinbiao, Sims, Emily, Borneo, Jovencio, Kondo, Takako, Ramdas, Baskar, Mali, Raghuveer Singh, Li, Shuo, Hashino, Eri, Takemoto, Clifford, Kapur, Reuben

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Deficiency of Src family kinases compromises the repopulating ability of hematopoietic stem cells by Orschell, Christie M, Borneo, Jovencio, Munugalavadla, Veerendra, Ma, Peilin, Sims, Emily, Ramdas, Baskar, Yoder, Mervin C, Kapur, Reuben

“…Objective Src family kinases (SFK) have been implicated in regulating growth factor and integrin-induced proliferation, migration, and gene expression in…”
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Rapid Preparation of Antifreezing Conductive Hydrogels for Flexible Strain Sensors and Supercapacitors by Song, Yating, Niu, Li, Ma, Peilin, Li, Xu, Feng, Jacko, Liu, Zhiming

“…Conductive hydrogels have shown great promise in flexible electronics, but their practical applications may be impeded by the time-consuming and…”
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Epoxy Fiber Derived All‐Polymer Films for High Performance Electrostatic Energy Storage Dielectrics by Xu, Pengpeng, Ma, Peilin, Yu, Junyi, Jiang, Kelun, Ke, Shanming, Huang, Haitao, Yu, Shuhui, Zhou, Yangbo, Luo, Suibin

“…Dielectric films with high discharged energy density are highly desired in electrical and electronic systems. Adding inorganic nanoparticles, especially for 1D…”
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Preparation of C–SiC/ZrSixOyCz core-shell fibers by Coaxial electrospinning and the high-temperature performance by Rui, Jianming, Li, Jing, Li, Yajing, Liu, Hongli, Zhang, Yinhao, Huang, Jie, Ma, Peilin, Chen, Zhong

“…Core-shell ceramics fibers with multiple composition are ideal candidates for thermal insulation application at high temperature. Herein, ultrathin…”
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Iberdomide Enhances Dara Mediated Cytotoxicity through Upregulation of CDC Activity and Elevated NK Cell Mediated ADCC by Ma, Peilin, Sridharan, Vinidhra, Wollerman, Krista, Dutta, Debjani, Singh, Ram Kumar, Mukherjee, Sambuddo, Bjorklund, Chad C., Hagner, Patrick R, Amatangelo, Michael, Gandhi, Anita K.

“…Background: Multiple Myeloma (MM) is an incurable hematological malignancy with current treatments comprising combination regimens, typically featuring…”
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Strong Adhesion of Electroless Plated Copper by Optimizing Lamination Temperature of Epoxy Composite Film for Advanced Chip Packaging Substrates by Luo, Suibin, Yu, Junyi, Ma, Peilin, Gao, Chunbo, Li, Peng, Zhu, Chuanxi, Yang, Yiquan, Xu, Pengpeng, Yang, Jie, Sun, Rong, Yu, Shuhui

“…Semi‐additive process (SAP) is a pivotal technique for fabricating integrated circuit (IC) packaging substrates, achieving fine line/space resolution below 20…”
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Preclinical and Translational Biomarker Analyses to Inform Clinical Development of Mezigdomide (CC-92480) in Combination with Dexamethasone and Daratumumab in Multiple Myeloma by Chow, Tracy T., Amatangelo, Michael, Ma, Peilin, Bjorklund, Chad C., Wollerman, Krista, Civardi, Tiziana, Koo, Phillip, Zhu, Yue, Maciag, Paulo, Katz, Jessica, Raval, Aparna, Oriol, Albert, Orlowski, Robert Z., White, Darrell, Richardson, Paul G., Gandhi, Anita K.

“…Introduction: Mezigdomide (MEZI) is a novel, oral cereblon (CRBN) E3 ligase modulator (CELMoD) that induces rapid and potent degradation of lkaros and Aiolos…”
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S6K1 regulates hematopoietic stem cell self-renewal and leukemia maintenance by Ghosh, Joydeep, Kobayashi, Michihiro, Ramdas, Baskar, Chatterjee, Anindya, Ma, Peilin, Mali, Raghuveer Singh, Carlesso, Nadia, Liu, Yan, Plas, David R, Chan, Rebecca J, Kapur, Reuben

“…Hyperactivation of the mTOR pathway impairs hematopoietic stem cell (HSC) functions and promotes leukemogenesis. mTORC1 and mTORC2 differentially control…”
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Nanoformulation of Paclitaxel: Exploring the Cyclodextrin / PLGA Nano Delivery Carrier to Slow Down Paclitaxel Release, Enhance Accumulation in Vivo by Ma, Peilin, Huang, JiaYing, Liu, Jinling, Zhu, Yi, Chen, Jiahong, Chen, Junming, Lei, Lunwen, Guan, Ziyun, Ban, Junfeng, Lu, Zhufen

“…Improving the aggregation and penetration in tumor sites increases the anti-tumor efficacy of nanomedicine. In the current study, we designed cyclodextrin…”
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