Comparison of clinical and pathological characteristics between screen-detected and self-detected breast cancers: a Hong Kong study

Breast cancer is the leading cause of death of Hong Kong women with increasing incidence. This study aimed to determine any prognostic differences between screen-detected and self-detected cases of breast cancer in a cohort of Hong Kong patients. This was a case series with internal comparison carri...

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Bibliographic Details
Published in:	Hong Kong medical journal = Xianggang yi xue za zhi Vol. 22; no. 3; pp. 202 - 209
Main Authors:	Lau, S Ss, Cheung, P Sy, Wong, T T, Ma, M Kg, Kwan, W H
Format:	Journal Article
Language:	English
Published:	China Hong Kong Academy of Medicine 01-06-2016
Subjects:	Adult Age Age Distribution Aged Aged, 80 and over Breast cancer Breast Neoplasms - diagnostic imaging Breast Neoplasms - pathology Breast Neoplasms - therapy Breast Self-Examination Carcinoma, Intraductal, Noninfiltrating - diagnostic imaging Carcinoma, Intraductal, Noninfiltrating - pathology Carcinoma, Intraductal, Noninfiltrating - therapy Confounding (Statistics) Cost analysis Data analysis Early Detection of Cancer - statistics & numerical data Female Histology Hong Kong Hospitals Humans Logistic Models Lumpectomy Lymph Nodes - pathology Lymphatic system Mammography Mastectomy Medical prognosis Medical screening Middle Aged Multivariate Analysis Patients Population Prognosis Regression analysis Retrospective Studies Surgery Trends Tumors Womens health Young Adult Hong Kong China United States > US China Breast self-examination Mammography Breast neoplasms/diagnosis
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Summary:	Breast cancer is the leading cause of death of Hong Kong women with increasing incidence. This study aimed to determine any prognostic differences between screen-detected and self-detected cases of breast cancer in a cohort of Hong Kong patients. This was a case series with internal comparison carried out in a private hospital in Hong Kong. Approximately 3000 cases of Chinese patients diagnosed with ductal carcinoma in situ or invasive breast cancer were reviewed. The screen-detected group showed better pathological characteristics than the self-detected group. Number of lymph nodes involved, invasive tumour size, and tumour grade were more favourable in the screen-detected group. There was also a lower proportion of patients with pure invasive ductal carcinoma and mastectomy in the screen-detected group. This study provides indirect evidence that women in the local population may gain clinical benefit from regular breast cancer screening. The findings need to be validated in a representative population of Hong Kong women.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1024-2708 2226-8707
DOI:	10.12809/hkmj154575