Search Results - "Ma, Kangtao"
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MiR-499 regulates cell proliferation and apoptosis during late-stage cardiac differentiation via Sox6 and cyclin D1
Published in PloS one (11-09-2013)“…MiR-499 is a cardiac-abundant miRNA. However, the biological functions of miR-499 in differentiated cardiomyocytes or in the cardiomyocyte differentiation…”
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SOX6 and PDCD4 enhance cardiomyocyte apoptosis through LPS-induced miR-499 inhibition
Published in Apoptosis (London) (01-02-2016)“…Sepsis-induced cardiac apoptosis is one of the major pathogenic factors in myocardial dysfunction. As it enhances numerous proinflammatory factors,…”
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3
ISL1 and JMJD3 synergistically control cardiac differentiation of embryonic stem cells
Published in Nucleic acids research (19-08-2016)“…ISL1 is expressed in cardiac progenitor cells and plays critical roles in cardiac lineage differentiation and heart development. Cardiac progenitor cells hold…”
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Comparative analysis of mesenchymal stem cells from bone marrow, cartilage, and adipose tissue
Published in Stem cells and development (01-08-2008)“…Mesenchymal stem cells (MSCs) isolated from bone marrow (BM), cartilage, and adipose tissue (AT) possess the capacity for self-renewal and the potential for…”
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ISL1 promotes pancreatic islet cell proliferation
Published in PloS one (04-08-2011)“…Islet 1 (ISL1), a LIM-homeodomain transcription factor is essential for promoting pancreatic islets proliferation and maintaining endocrine cells survival in…”
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ISL-1 is overexpressed in non-Hodgkin lymphoma and promotes lymphoma cell proliferation by forming a p-STAT3/p-c-Jun/ISL-1 complex
Published in Molecular cancer (29-07-2014)“…Insulin enhancer binding protein-1 (ISL-1), a LIM-homeodomain transcription factor, is essential for the heart, motor neuron and pancreas development…”
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Mesenchymal stem cells modified with angiopoietin-1 improve remodeling in a rat model of acute myocardial infarction
Published in Biochemical and biophysical research communications (08-06-2007)“…We used human angiopoietin-1 (hAng1)-modified mesenchymal stem cells (MSCs) to treat acute myocardial infarction (AMI) in rats. The hAng1 gene was transfected…”
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Angiopoietin-1/Tie2 signaling pathway inhibits lipopolysaccharide-induced activation of RAW264.7 macrophage cells
Published in Biochemical and biophysical research communications (05-02-2010)“…Angiopoietin-1 (Ang1) is a ligand for the endothelial-specific tyrosine kinase receptor Tie2 and has been shown to play an essential role in embryonic…”
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Inhibitor of DNA binding 1 (Id1) induces differentiation and proliferation of mouse embryonic carcinoma P19CL6 cells
Published in Biochemical and biophysical research communications (26-08-2011)“…► Id1 was upregulated during the cardiac differentiation process of P19CL6 cells. ► Id1 upregulated expression of cardiac specific genes Gata4, α-MHC and ISL1…”
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The synergistic effects of microfracture, perforated decalcified cortical bone matrix and adenovirus-bone morphogenetic protein-4 in cartilage defect repair
Published in Biomaterials (01-12-2008)“…Abstract We reported a technique for articular cartilage repair, consisting of microfracture, a biomaterial scaffold of perforated decalcified cortical bone…”
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α‐lipoic acid inhibits high glucose‐induced apoptosis in HIT‐T15 cells
Published in Development, growth & differentiation (01-06-2012)“…High blood glucose plays an important role in the pathogenesis of diabetes. α‐lipoic acid (LA) has been used to prevent and treat diabetes, and is thought to…”
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Angiopoietin-1 protects H9c2 cells from H2O2-induced apoptosis through AKT signaling
Published in Biochemical and biophysical research communications (03-08-2007)“…Loss of cardiomyocytes by apoptosis is proposed to cause ventricular remodeling and heart failure. Reactive oxygen species-induced apoptosis of cardiomyocytes…”
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13
Purified human bone marrow multipotent mesenchymal stem cells regenerate infarcted myocardium in experimental rats
Published in Cell transplantation (01-11-2005)“…Recent findings suggest the feasibility of cardiac repair by transplantation of bone marrow mesenchymal stem cell (MSCs). However, it remains controversial…”
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Long-term effects of bone marrow mononuclear cell transplantation on left ventricular function and remodeling in rats
Published in Life sciences (1973) (23-04-2004)“…This study was performed to evaluate the long-term effect on left ventricular function and remodeling in a rat model of bone marrow cell transplantation (BMT)…”
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Enhanced cytoprotection and angiogenesis by bone marrow cell transplantation may contribute to improved ischemic myocardial function
Published in European journal of cardio-thoracic surgery (01-02-2004)“…Objective: Heat shock proteins (HSPs) are cytoprotective proteins. Vascular endothelial growth factor (VEGF) is the most potent angiogenic factor. This study…”
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ISL1, a novel regulator of CCNB1, CCNB2 and c-MYC genes, promotes gastric cancer cell proliferation and tumor growth
Published in Oncotarget (14-06-2016)“…Islet-1 (ISL1) belongs to the LIM homeodomain transcription factor family, which is specifically expressed in certain tissue types only. Previously, we…”
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Autophagy eliminates cytoplasmic β-catenin and NICD to promote the cardiac differentiation of P19CL6 cells
Published in Cellular signalling (01-11-2014)“…Autophagy plays important roles in adipogenesis and neuron development. However, how autophagy contributes to cardiac development is not well understood. The…”
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miR-499 protects cardiomyocytes from H2O2-induced apoptosis via its effects on Pdcd4 and Pacs2
Published in RNA biology (01-04-2014)“…Background microRNAs (miRNAs) are a class of small, non-coding endogenous RNAs that post-transcriptionally regulate some protein-coding genes. miRNAs play an…”
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Cross-talk of SFRP4, integrin α1β1, and Notch1 inhibits cardiac differentiation of P19CL6 cells
Published in Cellular signalling (01-11-2016)“…Signaling pathways play an important role in cardiogenesis. Secreted frizzled-related protein 4 (SFRP4), a member of the Wnt family, contributes to…”
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ISL-1 promotes pancreatic islet cell proliferation by forming an ISL-1/Set7/9/PDX-1 complex
Published in Cell cycle (Georgetown, Tex.) (01-01-2015)“…Islet-1 (ISL-1), a LIM-homeodomain transcription factor, has been recently found to be essential for promoting postnatal pancreatic islet proliferation…”
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