Search Results - "Ma, Ida"
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Exposure–Response Analyses of Olaparib in Real-Life Patients with Ovarian Cancer
Published in Pharmaceutical research (01-05-2023)“…Background Olaparib is given in a fixed dose of twice-daily 300 mg in patients who are diagnosed with ovarian cancer, breast cancer, prostate cancer or…”
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Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data
Published in Cancer chemotherapy and pharmacology (01-07-2024)“…Purpose The number of patients with bariatric surgery who receive oral anticancer drugs is rising. Bariatric surgery may affect the absorption of oral…”
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Pharmacokinetic boosting of olaparib: A randomised, cross-over study (PROACTIVE-study)
Published in European journal of cancer (1990) (01-11-2023)“…Pharmacokinetic (PK) boosting is the intentional use of a drug-drug interaction to enhance systemic drug exposure. PK boosting of olaparib, a CYP3A-substrate,…”
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Research priority-setting for human, plant, and animal virology: an online experience for the Virology Institute of the Philippines
Published in Health research policy and systems (29-04-2021)“…Viral pandemics have had catastrophic consequences on population health and economies. The Philippine government intends to establish the Virology Institute of…”
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Assessment of the Biosafety and Biosecurity Landscape in the Philippines and the Development of the National Biorisk Management Framework
Published in Applied biosafety (01-12-2021)“…The emergence of biological threats that can potentially affect millions emphasizes the need to develop a policy framework in the Philippines that can mount an…”
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Discovery of Tetrahydropyrazolopyrimidine Carboxamide Derivatives As Potent and Orally Active Antitubercular Agents
Published in ACS medicinal chemistry letters (09-05-2013)“…Tetrahydropyrazolo[1,5-a]pyrimidine scaffold was identified as a hit series from a Mycobacterium tuberculosis (Mtb) whole cell high through-put screening (HTS)…”
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A Population Pharmacokinetic Study to Evaluate Doxorubicin Exposure Across All Age Groups
Published in Clinical pharmacokinetics (16-11-2024)“…The effect of age on doxorubicin pharmacokinetics remains inconclusive, especially in patients at the extremes of the age spectrum. We developed a population…”
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Cortisol as Biomarker for CYP17-Inhibition is Associated with Therapy Outcome of Abiraterone Acetate
Published in Pharmaceutical research (01-12-2023)“…Background Abiraterone acetate is an irreversible 17α-hydroxylase/C17, 20-lyase (CYP17) inhibitor approved for the treatment of metastatic castration-resistant…”
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A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy
Published in Nature communications (01-08-2010)“…Candidate antibacterials are usually identified on the basis of their in vitro activity. However, the apparent inhibitory activity of new leads can be…”
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External validity of an automated delirium prediction model (DEMO) and comparison to the manual VMS-questions: a retrospective cohort study
Published in International journal of clinical pharmacy (01-10-2023)“…Background It is estimated that one-third of delirium cases in hospitals could be prevented with appropriate interventions. In Dutch hospitals a manual…”
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Peptide deformylase inhibitors of Mycobacterium tuberculosis: Synthesis, structural investigations, and biological results
Published in Bioorganic & medicinal chemistry (15-12-2008)“…Bacterial peptide deformylase (PDF) belongs to a subfamily of metalloproteases catalyzing the removal of the N-terminal formyl group from newly synthesized…”
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[S4Cd17(SPh)28]2-, the first member of a third series of tetrahedral [SWMX(SR)y]z- clusters
Published in Journal of the American Chemical Society (01-07-1988)Get full text
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Mercury polysulfide complexes, [Hg(Sx)(Sy)]2-: syntheses, mercury-199 NMR studies in solution, and crystal structure of (Ph4P)4[Hg(S4)2]Br2
Published in Inorganic chemistry (01-01-1991)Get full text
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Barents-2.5km v2.0: an operational data-assimilative coupled ocean and sea ice ensemble prediction model for the Barents Sea and Svalbard
Published in Geoscientific Model Development (22-09-2023)“…An operational ocean and sea ice forecast model, Barents-2.5, is implemented for short-term forecasting at the coast off northern Norway, the Barents Sea, and…”
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