Search Results - "Ma, Honghui"
-
1
CDC-like kinase 4 deficiency contributes to pathological cardiac hypertrophy by modulating NEXN phosphorylation
Published in Nature communications (30-07-2022)“…Kinase-catalyzed phosphorylation plays a crucial role in pathological cardiac hypertrophy. Here, we show that CDC-like kinase 4 (CLK4) is a critical regulator…”
Get full text
Journal Article -
2
The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation
Published in Genes & development (15-06-2012)“…The histone H3 Lys 27 (H3K27) demethylase JMJD3 has been shown to play important roles in transcriptional regulation and cell differentiation. However, the…”
Get full text
Journal Article -
3
PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression
Published in Molecular cell (22-07-2011)“…Histone methylation occurs on both lysine and arginine residues, and its dynamic regulation plays a critical role in chromatin biology. Here we identify the…”
Get full text
Journal Article -
4
Sirtuin 6 maintains epithelial STAT6 activity to support intestinal tuft cell development and type 2 immunity
Published in Nature communications (03-09-2022)“…Dynamic regulation of intestinal epithelial cell (IEC) differentiation is crucial for both homeostasis and the response to helminth infection. SIRT6 belongs to…”
Get full text
Journal Article -
5
M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability
Published in Proceedings of the National Academy of Sciences - PNAS (27-03-2012)“…UHRF1 (Ubiquitin-like, with PHD and RING finger domains 1) plays an important role in DNA CpG methylation, heterochromatin function and gene expression…”
Get full text
Journal Article -
6
m6A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2
Published in Nature communications (25-11-2019)“…Dynamic mRNA modification in the form of N 6 -methyladenosine (m 6 A) adds considerable richness and sophistication to gene regulation. The m 6 A mark is…”
Get full text
Journal Article -
7
DNA Damage Regulates UHRF1 Stability via the SCFβ-TrCP E3 Ligase
Published in Molecular and Cellular Biology (01-03-2013)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
8
Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA
Published in Molecular cell (20-06-2019)“…N7-methylguanosine (m7G) is a positively charged, essential modification at the 5′ cap of eukaryotic mRNA, regulating mRNA export, translation, and splicing…”
Get full text
Journal Article -
9
YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA
Published in Cell research (20-01-2017)“…N6-methyladenosine (m6A) is the most abundant internal modification in eukaryotic messenger RNAs (mRNAs), and plays important roles in cell differentiation and…”
Get full text
Journal Article -
10
Modeling and Dynamic Analysis of Cutterhead Driving System in Tunnel Boring Machine
Published in Shock and vibration (01-01-2017)“…Failure of cutterhead driving system (CDS) of tunnel boring machine (TBM) often occurs under shock and vibration conditions. To investigate the dynamic…”
Get full text
Journal Article -
11
Binding to m6A RNA promotes YTHDF2-mediated phase separation
Published in Protein & cell (01-04-2020)Get full text
Journal Article -
12
Ythdc2 is an N^6-methyladenosine binding protein that regulates mammalian spermatogenesis
Published in Cell research (01-09-2017)“…N^6-methyladenosine (m^6A) is the most common internal modification in eukaryotic mRNA. It is dynamically in- stalled and removed, and acts as a new layer of…”
Get full text
Journal Article -
13
The presence of Bacillus thuringiensis ( Bt) protein in earthworms Eisenia fetida has no deleterious effects on their growth and reproduction
Published in Chemosphere (Oxford) (01-11-2011)“…► No significant difference was found in survival rate of Eisenia fetida. ► A significantly positive effect was observed in growth of E. fetida. ► A…”
Get full text
Journal Article -
14
Oligo-microarray analysis reveals the role of cyclophilin A in drug resistance
Published in Cancer chemotherapy and pharmacology (01-03-2008)“…Cyclophilin A (CYPA) belongs to peptidyl prolyl isomerases (PPIases), which catalyze the cis / trans isomerization of prolyl peptide bonds in cellular…”
Get full text
Journal Article -
15
Protective effects of a novel trimerized sTNFRII on acute liver injury
Published in International immunopharmacology (01-05-2012)“…TNF α plays a central role in the pathogenesis of inflammatory diseases such as rheumatoid arthritis and murine acute liver injury induced by injection of…”
Get full text
Journal Article -
16
YTHDF3 facilitates translation and decay of N 6 -methyladenosine-modified RNA
Published in Cell research (01-03-2017)“…N -methyladenosine (m A) is the most abundant internal modification in eukaryotic messenger RNAs (mRNAs), and plays important roles in cell differentiation and…”
Get full text
Journal Article -
17
N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency
Published in Cell (04-06-2015)“…N(6)-methyladenosine (m(6)A) is the most abundant internal modification in mammalian mRNA. This modification is reversible and non-stoichiometric and adds…”
Get full text
Journal Article -
18
Transcriptome-wide Mapping of Internal N 7 -Methylguanosine Methylome in Mammalian mRNA
Published in Molecular cell (20-06-2019)“…N -methylguanosine (m G) is a positively charged, essential modification at the 5' cap of eukaryotic mRNA, regulating mRNA export, translation, and splicing. m…”
Get full text
Journal Article -
19
Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis
Published in Cell research (01-09-2017)“…N 6 -methyladenosine (m 6 A) is the most common internal modification in eukaryotic mRNA. It is dynamically installed and removed, and acts as a new layer of…”
Get full text
Journal Article -
20
METTL3 regulates heterochromatin in mouse embryonic stem cells
Published in Nature (London) (11-03-2021)“…METTL3 (methyltransferase-like 3) mediates the N 6 -methyladenosine (m 6 A) methylation of mRNA, which affects the stability of mRNA and its translation into…”
Get full text
Journal Article