Search Results - "Ma, Fanxin"
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Antagonist anti-LIF antibody derived from naive human scFv phage library inhibited tumor growth in mice
Published in BMC immunology (22-08-2024)“…Leukemia inhibitory factor (LIF) is a multifunctional member of the IL-6 cytokine family that activates downstream signaling pathways by binding to the…”
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FTL004, an anti-CD38 mAb with negligible RBC binding and enhanced pro-apoptotic activity, is a novel candidate for treatments of multiple myeloma and non-Hodgkin lymphoma
Published in Journal of hematology and oncology (29-12-2022)“…Anti-CD38 monoclonal antibodies (mAbs), daratumumab, and isatuximab have represented a breakthrough in the treatment of multiple myeloma (MM). Recently,…”
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Endothelial cell-specific molecule 2 (ECSM2) localizes to cell-cell junctions and modulates bFGF-directed cell migration via the ERK-FAK pathway
Published in PloS one (24-06-2011)“…Despite its first discovery by in silico cloning of novel endothelial cell-specific genes a decade ago, the biological functions of endothelial cell-specific…”
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Structural and functional characterization of two alternative splicing variants of mouse Endothelial Cell-Specific Chemotaxis Regulator (ECSCR)
Published in International journal of molecular sciences (01-04-2012)“…Endothelial cells (ECs) that line the lumen of blood vessels are important players in blood vessel formation, and EC migration is a key component of the…”
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Endothelial cell-specific molecule 2 (ECSM2) modulates actin remodeling and epidermal growth factor receptor signaling
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-03-2009)“…Endothelial cell-specific molecules (ECSMs) play a pivotal role in the pathogenesis of many angiogenesis-related diseases. Since its initial discovery, the…”
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Signaling Cross Talk between Growth Hormone (GH) and Insulin-Like Growth Factor-I (IGF-I) in Pancreatic Islet β-Cells
Published in Molecular endocrinology (Baltimore, Md.) (01-12-2011)“…Dysfunction and destruction of pancreatic islet β-cells is a hallmark of diabetes. Better understanding of cell signals regulating β-cell growth and…”
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Effective antitumor activity of 5T4‐specific CAR‐T cells against ovarian cancer cells in vitro and xenotransplanted tumors in vivo
Published in MedComm (2020) (01-12-2020)“…Ovarian cancer is considered to be the most lethal gynecologic malignancy, and despite the development of conventional therapies and new therapeutic…”
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Endothelial Cell-Specific Molecule 2
Published in PloS one (24-06-2011)“…Background Despite its first discovery by in silico cloning of novel endothelial cell-specific genes a decade ago, the biological functions of endothelial…”
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A critical role of vascular endothelial growth factor D in zebrafish embryonic vasculogenesis and angiogenesis
Published in Biochemical and biophysical research communications (15-06-2007)“…The VEGF family comprises seven members that are designated VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, placental growth factor (PlGF), and VEGF-F. Of these…”
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