Search Results - "Ma, Chunlong"

Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease by Ma, Chunlong, Sacco, Michael Dominic, Hurst, Brett, Townsend, Julia Alma, Hu, Yanmei, Szeto, Tommy, Zhang, Xiujun, Tarbet, Bart, Marty, Michael Thomas, Chen, Yu, Wang, Jun

“…A new coronavirus SARS-CoV-2, also called novel coronavirus 2019 (2019-nCoV), started to circulate among humans around December 2019, and it is now widespread…”
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Invalidation of dieckol and 1,2,3,4,6-pentagalloylglucose (PGG) as SARS-CoV-2 main protease inhibitors and the discovery of PGG as a papain-like protease inhibitor by Tan, Haozhou, Ma, Chunlong, Wang, Jun

“…The COVID-19 pandemic spurred a broad interest in antiviral drug discovery. The SARS-CoV-2 main protease (M pro ) and papain-like protease (PL pro ) are…”
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Expedited Approach toward the Rational Design of Noncovalent SARS-CoV‑2 Main Protease Inhibitors by Kitamura, Naoya, Sacco, Michael Dominic, Ma, Chunlong, Hu, Yanmei, Townsend, Julia Alma, Meng, Xiangzhi, Zhang, Fushun, Zhang, Xiujun, Ba, Mandy, Szeto, Tommy, Kukuljac, Adis, Marty, Michael Thomas, Schultz, David, Cherry, Sara, Xiang, Yan, Chen, Yu, Wang, Jun

“…The main protease (Mpro) of SARS-CoV-2 is a validated antiviral drug target. Several Mpro inhibitors have been reported with potent enzymatic inhibition and…”
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Expeditious Lead Optimization of Isoxazole-Containing Influenza A Virus M2-S31N Inhibitors Using the Suzuki–Miyaura Cross-Coupling Reaction by Li, Fang, Hu, Yanmei, Wang, Yuanxiang, Ma, Chunlong, Wang, Jun

“…The existence of multidrug-resistant influenza viruses, coupled with the continuously antigenic shift and antigenic drift of influenza viruses, necessitates…”
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Validation and invalidation of SARS-CoV-2 main protease inhibitors using the Flip-GFP and Protease-Glo luciferase assays by Ma, Chunlong, Tan, Haozhou, Choza, Juliana, Wang, Yuyin, Wang, Jun

“…SARS-CoV-2 main protease (Mpro) is one of the most extensively exploited drug targets for COVID-19. Structurally disparate compounds have been reported as Mpro…”
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Ebselen, Disulfiram, Carmofur, PX-12, Tideglusib, and Shikonin Are Nonspecific Promiscuous SARS-CoV‑2 Main Protease Inhibitors by Ma, Chunlong, Hu, Yanmei, Townsend, Julia Alma, Lagarias, Panagiotis I, Marty, Michael Thomas, Kolocouris, Antonios, Wang, Jun

“…Among the drug targets being investigated for SARS-CoV-2, the viral main protease (Mpro) is one of the most extensively studied. Mpro is a cysteine protease…”
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Research on the mechanism of laser drilling alumina ceramics in shallow water by Li, Guangliang, Shi, Dongyan, Hu, Shanshan, Ma, Chunlong, He, Dongze, Yao, Kai

“…Underwater laser drilling of alumina ceramics is an effective means to improve the quality of holes in the material. In the process of underwater laser…”
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Pharmacological Characterization of the Spectrum of Antiviral Activity and Genetic Barrier to Drug Resistance of M2-S31N Channel Blockers by Ma, Chunlong, Zhang, Jiantao, Wang, Jun

“…Adamantanes (amantadine and rimantadine) are one of the two classes of Food and Drug Administration-approved antiviral drugs used for the prevention and…”
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Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus by Wang, Jun, Wu, Yibing, Ma, Chunlong, Fiorin, Giacomo, Wang, Jizhou, Pinto, Lawrence H., Lamb, Robert A., Klein, Michael L., DeGrado, William F.

“…The influenza A virus M2 proton channel (A/M2) is the target of the antiviral drugs amantadine and rimantadine, whose use has been discontinued due to…”
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Design and expeditious synthesis of organosilanes as potent antivirals targeting multidrug-resistant influenza A viruses by Hu, Yanmei, Wang, Yuanxiang, Li, Fang, Ma, Chunlong, Wang, Jun

“…The efficacy of current influenza vaccines and small molecule antiviral drugs is curtailed by the emerging of multidrug-resistant influenza viruses. As…”
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Free Vibration Analysis of Closed Moderately Thick Cross-Ply Composite Laminated Cylindrical Shell with Arbitrary Boundary Conditions by Shi, Dongyan, He, Dongze, Wang, Qingshan, Ma, Chunlong, Shu, Haisheng

“…A semi-analytic method is adopted to analyze the free vibration characteristics of the moderately thick composite laminated cylindrical shell with arbitrary…”
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Experimental Research on the Influence of Different Curved Rigid Boundaries on Electric Spark Bubbles by Ma, Chunlong, Shi, Dongyan, Chen, Yingyu, Cui, Xiongwei, Wang, Mengnan

“…It is well known that the bubble dynamics and load characteristics of cavitation bubbles depend to a great extent on their proximity to the boundary. The…”
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Discovery of SARS-CoV‑2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay by Ma, Chunlong, Sacco, Michael Dominic, Xia, Zilei, Lambrinidis, George, Townsend, Julia Alma, Hu, Yanmei, Meng, Xiangzhi, Szeto, Tommy, Ba, Mandy, Zhang, Xiujun, Gongora, Maura, Zhang, Fushun, Marty, Michael Thomas, Xiang, Yan, Kolocouris, Antonios, Chen, Yu, Wang, Jun

“…The papain-like protease (PLpro) of SARS-CoV-2 is a validated antiviral drug target. Through a fluorescence resonance energy transfer-based high-throughput…”
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Free vibration characteristics and wave propagation analysis in nonlocal functionally graded cylindrical nanoshell using wave-based method by He, Dongze, Shi, Dongyan, Wang, Qingshan, Ma, Chunlong

“…In this article, the free vibration characteristics and wave propagation analysis of functionally graded materials (FGM) cylindrical nanoshell is investigated…”
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Wave propagation in magneto-electro-thermo-elastic nanobeams based on nonlocal theory by He, Dongze, Shi, Dongyan, Wang, Qingshan, Ma, Chunlong

“…In this article, wave based method (WBM) is proposed as a new semi-analytical method to analyze the wave propagation characteristics of the…”
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Wave Based Method for Free Vibration Analysis of Cross-Ply Composite Laminated Shallow Shells with General Boundary Conditions by Shi, Dongyan, He, Dongze, Wang, Qingshan, Ma, Chunlong, Shu, Haisheng

“…In this paper, a semi-analytical method is adopted to analyze the free vibration characteristics of composite laminated shallow shells under general boundary…”
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Cytopathic Effect Assay and Plaque Assay to Evaluate in vitro Activity of Antiviral Compounds Against Human Coronaviruses 229E, OC43, and NL63 by Hu, Yanmei, Ma, Chunlong, Wang, Jun

“…Coronaviruses are important human pathogens, among which the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent for the…”
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A New Measurement Based on HPB to Measure the Wall Pressure of Electric-Spark-Generated Bubble near the Hemispheric Boundary by Chen, Yingyu, Cui, Xiongwei, Shi, Dongyan, Ma, Chunlong

“…Direct measurement of the wall pressure loading of the spherical boundary subjected to the near-field underwater explosion is a great difficulty. To…”
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The Amphipathic Helix of Influenza A Virus M2 Protein Is Required for Filamentous Bud Formation and Scission of Filamentous and Spherical Particles by Roberts, Kari L, Leser, George P, Ma, Chunlong, Lamb, Robert A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Chemical Genomics Approach Leads to the Identification of Hesperadin, an Aurora B Kinase Inhibitor, as a Broad-Spectrum Influenza Antiviral by Hu, Yanmei, Zhang, Jiantao, Musharrafieh, Rami, Hau, Raymond, Ma, Chunlong, Wang, Jun

“…Influenza viruses are respiratory pathogens that are responsible for annual influenza epidemics and sporadic influenza pandemics. Oseltamivir (Tamiflu ) is…”
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