Search Results - "Ma, Che"

Better influenza vaccines: an industry perspective by Chen, Juine-Ruey, Liu, Yo-Min, Tseng, Yung-Chieh, Ma, Che

“…Vaccination is the most effective measure at preventing influenza virus infections. However, current seasonal influenza vaccines are only protective against…”
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Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient by Zhou, Daming, Duyvesteyn, Helen M. E., Chen, Cheng-Pin, Huang, Chung-Guei, Chen, Ting-Hua, Shih, Shin-Ru, Lin, Yi-Chun, Cheng, Chien-Yu, Cheng, Shu-Hsing, Huang, Yhu-Chering, Lin, Tzou-Yien, Ma, Che, Huo, Jiandong, Carrique, Loic, Malinauskas, Tomas, Ruza, Reinis R., Shah, Pranav N. M., Tan, Tiong Kit, Rijal, Pramila, Donat, Robert F., Godwin, Kerry, Buttigieg, Karen R., Tree, Julia A., Radecke, Julika, Paterson, Neil G., Supasa, Piyada, Mongkolsapaya, Juthathip, Screaton, Gavin R., Carroll, Miles W., Gilbert-Jaramillo, Javier, Knight, Michael L., James, William, Owens, Raymond J., Naismith, James H., Townsend, Alain R., Fry, Elizabeth E., Zhao, Yuguang, Ren, Jingshan, Stuart, David I., Huang, Kuan-Ying A.

“…The COVID-19 pandemic has had an unprecedented health and economic impact and there are currently no approved therapies. We have isolated an antibody, EY6A,…”
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Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection by Jan, Jia-Tsrong, Cheng, Ting-Jen Rachel, Juang, Yu-Pu, Ma, Hsiu-Hua, Wu, Ying-Ta, Yang, Wen-Bin, Cheng, Cheng-Wei, Chen, Xiaorui, Chou, Ting-Hung, Shie, Jiun-Jie, Cheng, Wei-Chieh, Chein, Rong-Jie, Mao, Shi-Shan, Liang, Pi-Hui, Ma, Che, Hung, Shang-Cheng, Wong, Chi-Huey

“…The outbreak of COVID-19 caused by SARS-CoV-2 has resulted in more than 50 million confirmed cases and over 1 million deaths worldwide as of November 2020…”
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Superior Pitting Corrosion Resistance of Ultra-high Strength Low Alloy Steel Via Co-alloying Al and Cu by Che, Ma-jun, Du, Xiao-jie, Yi, Shuo, Ma, Hou-yu, He, Yi-zhu

“…Advanced high-strength low alloy (HSLA) steels with outstanding corrosion resistance are extensively applied in marine engineering. However, corrosion…”
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A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2 by Liu, Yo-Min, Shahed-Al-Mahmud, Md, Chen, Xiaorui, Chen, Ting-Hua, Liao, Kuo-Shiang, Lo, Jennifer M., Wu, Yi-Min, Ho, Meng-Chiao, Wu, Chung-Yi, Wong, Chi-Huey, Jan, Jia-Tsrong, Ma, Che

“…The influenza virus hemagglutinin (HA) and coronavirus spike (S) protein mediate virus entry. HA and S proteins are heavily glycosylated, making them potential…”
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A common glycan structure on immunoglobulin G for enhancement of effector functions by Lin, Chin-Wei, Tsai, Ming-Hung, Li, Shiou-Ting, Tsai, Tsung-I, Chu, Kuo-Ching, Liu, Ying-Chih, Lai, Meng-Yu, Wu, Chia-Yu, Tseng, Yung-Chieh, Shivatare, Sachin S., Wang, Chia-Hung, Chao, Ping, Wang, Shi-Yun, Shih, Hao-Wei, Zeng, Yi-Fang, You, Tsai-Hong, Liao, Jung-Yu, Tu, Yu-Chen, Lin, Yih-Shyan, Chuang, Hong-Yang, Chen, Chia-Lin, Tsai, Charng-Sheng, Huang, Chiu-Chen, Lin, Nan-Horng, Ma, Che, Wu, Chung-Yi, Wong, Chi-Huey

“…Antibodies have been developed as therapeutic agents for the treatment of cancer, infection, and inflammation. In addition to binding activity toward the…”
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Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome by Nguyen, Hong Thuy Vy, Chen, Xiaorui, Parada, Claudia, Luo, An-Chi, Shih, Orion, Jeng, U-Ser, Huang, Chia-Ying, Shih, Yu-Ling, Ma, Che

“…The synthesis of the cell-wall peptidoglycan during bacterial cell division is mediated by a multiprotein machine, called the divisome. The essential membrane…”
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Breadth and function of antibody response to acute SARS-CoV-2 infection in humans by Huang, Kuan-Ying A, Tan, Tiong Kit, Chen, Ting-Hua, Huang, Chung-Guei, Harvey, Ruth, Hussain, Saira, Chen, Cheng-Pin, Harding, Adam, Gilbert-Jaramillo, Javier, Liu, Xu, Knight, Michael, Schimanski, Lisa, Shih, Shin-Ru, Lin, Yi-Chun, Cheng, Chien-Yu, Cheng, Shu-Hsing, Huang, Yhu-Chering, Lin, Tzou-Yien, Jan, Jia-Tsrong, Ma, Che, James, William, Daniels, Rodney S, McCauley, John W, Rijal, Pramila, Townsend, Alain R

“…Serological and plasmablast responses and plasmablast-derived IgG monoclonal antibodies (MAbs) have been analysed in three COVID-19 patients with different…”
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X-ray structure of EmrE supports dual topology model by Chen, Yen-Ju, Pornillos, Owen, Lieu, Samantha, Ma, Che, Chen, Andy P, Chang, Geoffrey

“…EmrE, a multidrug transporter from Escherichia coli, functions as a homodimer of a small four-transmembrane protein. The membrane insertion topology of the two…”
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Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2 by Huang, Kuan-Ying A., Chen, Xiaorui, Mohapatra, Arpita, Nguyen, Hong Thuy Vy, Schimanski, Lisa, Tan, Tiong Kit, Rijal, Pramila, Vester, Susan K., Hills, Rory A., Howarth, Mark, Keeffe, Jennifer R., Cohen, Alexander A., Kakutani, Leesa M., Wu, Yi-Min, Shahed-Al-Mahmud, Md, Chou, Yu-Chi, Bjorkman, Pamela J., Townsend, Alain R., Ma, Che

“…Antibody-mediated immunity plays a crucial role in protection against SARS-CoV-2 infection. We isolated a panel of neutralizing anti-receptor-binding domain…”
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The presence of broadly neutralizing anti-SARS-CoV-2 RBD antibodies elicited by primary series and booster dose of COVID-19 vaccine by Chen, Xiaorui, Mohapatra, Arpita, Nguyen, Hong Thuy Vy, Schimanski, Lisa, Kit Tan, Tiong, Rijal, Pramila, Chen, Cheng-Pin, Cheng, Shu-Hsing, Lee, Wen-Hsin, Chou, Yu-Chi, Townsend, Alain R, Ma, Che, Huang, Kuan-Ying A

“…Antibody-mediated immunity plays a key role in protection against SARS-CoV-2. We characterized B-cell-derived anti-SARS-CoV-2 RBD antibody repertoires from…”
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A non-neutralizing antibody broadly protects against influenza virus infection by engaging effector cells by Ko, Yi-An, Yu, Yueh-Hsiang, Wu, Yen-Fei, Tseng, Yung-Chieh, Chen, Chia-Lin, Goh, King-Siang, Liao, Hsin-Yu, Chen, Ting-Hua, Cheng, Ting-Jen Rachel, Yang, An-Suei, Wong, Chi-Huey, Ma, Che, Lin, Kuo-I

“…Hemagglutinin (HA) is the immunodominant protein of the influenza virus. We previously showed that mice injected with a monoglycosylated influenza A HA (HA mg…”
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Glycans on Influenza Hemagglutinin Affect Receptor Binding and Immune Response by Wang, Cheng-Chi, Chen, Juine-Ruey, Tseng, Yung-Chieh, Hsu, Che-Hsiung, Hung, Yu-Fu, Chen, Shih-Wei, Chen, Chin-Mei, Khoo, Kay-Hooi, Cheng, Ting-Jen, Cheng, Yih-Shyun E., Jan, Jia-Tsrong, Wu, Chung-Yi, Ma, Che, Wong, Chi-Huey

“…Recent cases of avian influenza H5N1 and the swine-origin 2009 H1N1 have caused a great concern that a global disaster like the 1918 influenza pandemic may…”
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Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli by Sung, Ming-Ta, Lai, Yen-Ting, Huang, Chia-Ying, Chou, Lien-Yang, Shih, Hao-Wei, Cheng, Wei-Chieh, Wong, Chi-Huey, Ma, Che

“…Drug-resistant bacteria have caused serious medical problems in recent years, and the need for new antibacterial agents is undisputed. Transglycosylase, a…”
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Exome sequencing in paediatric patients with movement disorders by Kwong, Anna Ka-Yee, Tsang, Mandy Ho-Yin, Fung, Jasmine Lee-Fong, Mak, Christopher Chun-Yu, Chan, Kate Lok-San, Rodenburg, Richard J T, Lek, Monkol, Huang, Shushu, Pajusalu, Sander, Yau, Man-Mut, Tsoi, Cheung, Fung, Sharon, Liu, Kam-Tim, Ma, Che-Kwan, Wong, Sheila, Yau, Eric Kin-Cheong, Tai, Shuk-Mui, Fung, Eva Lai-Wah, Wu, Nick Shun-Ping, Tsung, Li-Yan, Smeitink, Jan, Chung, Brian Hon-Yin, Fung, Cheuk-Wing

“…Movement disorders are a group of heterogeneous neurological diseases including hyperkinetic disorders with unwanted excess movements and hypokinetic disorders…”
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Vaccinia virus-based vaccines confer protective immunity against SARS-CoV-2 virus in Syrian hamsters by Kulkarni, Rakesh, Chen, Wen-Ching, Lee, Ying, Kao, Chi-Fei, Hu, Shiu-Lok, Ma, Hsiu-Hua, Jan, Jia-Tsrong, Liao, Chun-Che, Liang, Jian-Jong, Ko, Hui-Ying, Sun, Cheng-Pu, Lin, Yin-Shoiou, Wang, Yu-Chiuan, Wei, Sung-Chan, Lin, Yi-Ling, Ma, Che, Chao, Yu-Chan, Chou, Yu-Chi, Chang, Wen

“…COVID-19 in humans is caused by Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that belongs to the beta family of coronaviruses. SARS-CoV-2…”
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Temperature dependence of deformation mechanisms of a new Ni-based superalloy and high-temperature property optimization by Zhao, Pengfei, Zhu, Heyu, Hou, Kunlei, Wang, Min, Hao, Xianchao, Xing, Weiwei, Gao, Ming, Chen, Xing-Qiu, Ma, Ying-Che

“…The influence of temperature on the deformation mechanisms of a new Ni-based superalloy named K4800 containing 35 vol% γ′ were investigated. We studied the…”
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Structural and Physical Basis for Anti-IgE Therapy by Wright, Jon D., Chu, Hsing-Mao, Huang, Chun-Hsiang, Ma, Che, Wen Chang, Tse, Lim, Carmay

“…Omalizumab, an anti-IgE antibody, used to treat severe allergic asthma and chronic idiopathic urticaria, binds to IgE in blood or membrane-bound on B…”
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Vaccination of monoglycosylated hemagglutinin induces cross-strain protection against influenza virus infections by Chen, Juine-Ruey, Yu, Yueh-Hsiang, Tseng, Yung-Chieh, Chiang, Wan-Ling, Chiang, Ming-Feng, Ko, Yi-An, Chiu, Yi-Kai, Ma, Hsiu-Hua, Wu, Chung-Yi, Jan, Jia-Tsrong, Lin, Kuo-I, Ma, Che, Wong, Chi-Huey

“…The 2009 H1N1 pandemic and recent human cases of H5N1, H7N9, and H6N1 in Asia highlight the need for a universal influenza vaccine that can provide…”
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Vaccine design of hemagglutinin glycoprotein against influenza by Chen, Juine-Ruey, Ma, Che, Wong, Chi-Huey

“…Influenza viruses continue to cause annual epidemics and pose the threat of a deadly global pandemic. Vaccination has remained the best approach for prevention…”
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