Search Results - "Ma, Anna"

Dual HDAC and PI3K Inhibitor CUDC-907 Downregulates MYC and Suppresses Growth of MYC-dependent Cancers by Sun, Kaiming, Atoyan, Ruzanna, Borek, Mylissa A, Dellarocca, Steven, Samson, Maria Elena S, Ma, Anna W, Xu, Guang-Xin, Patterson, Troy, Tuck, David P, Viner, Jaye L, Fattaey, Ali, Wang, Jing

“…Upregulation of MYC is a common driver event in human cancers, and some tumors depend on MYC to maintain transcriptional programs that promote cell growth and…”
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Adolescent resilience and mobile phone addiction in Henan Province of China: Impacts of chain mediating, coping style by Ma, Anna, Yang, Yan, Guo, Shuangxi, Li, Xue, Zhang, Shenhua, Chang, Hongjuan

“…As mobile phone use grows, so it brings benefits and risks. As an important part of adolescents healthy growth, resilience plays an indispensable role. Thus,…”
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Genome-wide identification and expression analysis of SWEET gene family in Litchi chinensis reveal the involvement of LcSWEET2a/3b in early seed development by Xie, Hanhan, Wang, Dan, Qin, Yaqi, Ma, Anna, Fu, Jiaxin, Qin, Yonghua, Hu, Guibing, Zhao, Jietang

“…SWEETs (Sugar Will Eventually be Exported transporters) function as sugar efflux transporters that perform diverse physiological functions, including phloem…”
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CUDC-907 in relapsed/refractory diffuse large B-cell lymphoma, including patients with MYC-alterations: results from an expanded phase I trial by Oki, Yasuhiro, Kelly, Kevin R, Flinn, Ian, Patel, Manish R, Gharavi, Robert, Ma, Anna, Parker, Jefferson, Hafeez, Amir, Tuck, David, Younes, Anas

“…CUDC-907 is a first-in-class, oral small molecule inhibitor of both HDAC (class I and II) and PI3K (class Iα, β, and δ) enzymes, with demonstrated anti-tumor…”
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Genetic dissection of developmental responses of agro-morphological traits under different doses of nutrient fertilizers using high-density SNP markers by Mahender, Anumalla, Ali, Jauhar, Prahalada, G D, Sevilla, Ma Anna Lynn, Balachiranjeevi, C H, Md, Jamaloddin, Maqsood, Umer, Li, Zhikang

“…The production and productivity of rice (Oryza sativa L.) are primarily influenced by the application of the critical nutrients nitrogen (N), phosphorus (P),…”
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Cancer Network Disruption by a Single Molecule Inhibitor Targeting Both Histone Deacetylase Activity and Phosphatidylinositol 3-Kinase Signaling by CHANGGENG QIAN, LAI, Cheng-Jung, ZIFCAK, Brian, ANNA WAI SEE MA, DELLAROCCA, Steven, BOREK, Mylissa, ZHAI, Hai-Xiao, XIONG CAI, VOI, Maurizio, RUDI BAO, WANG, Da-Gong, JING WANG, XU, Guang-Xin, ATOYAN, Ruzanna, HUI QU, LING YIN, SAMSON, Maria

“…Given that histone deacetylase (HDAC) inhibitors are known to induce multiple epigenetic modifications affecting signaling networks and act synergistically…”
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PUF60-related developmental disorder: A case series and phenotypic analysis of 10 additional patients with monoallelic PUF60 variants by Grimes, H, Ansari, M, Ashraf, T, Cueto-González, Anna Mª, Calder, A, Day, M, Fernandez Alvarez, P, Foster, A, Lahiri, N, Repetto, G M, Scurr, I, Varghese, V, Low, Karen J

“…PUF60-related developmental disorder (also referred to as Verheij syndrome), resulting from haploinsufficiency of PUF60, is associated with multiple congenital…”
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Safety, tolerability, and preliminary activity of CUDC-907, a first-in-class, oral, dual inhibitor of HDAC and PI3K, in patients with relapsed or refractory lymphoma or multiple myeloma: an open-label, dose-escalation, phase 1 trial by Younes, Anas, Dr, Berdeja, Jesus G, MD, Patel, Manish R, MD, Flinn, Ian, MD, Gerecitano, John F, MD, Neelapu, Sattva S, MD, Kelly, Kevin R, MD, Copeland, Amanda R, MSN, Akins, Amy, BSN, Clancy, Myles S, MBA, Gong, Lucy, PharmD, Wang, Jing, PhD, Ma, Anna, MS, Viner, Jaye L, MD, Oki, Yasuhiro, MD

“…Summary Background Treatment options for patients with relapsed or refractory lymphoma and multiple myeloma are limited. CUDC-907 is an oral, first-in-class,…”
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The Impact of Adolescent Resilience on Mobile Phone Addiction During COVID-19 Normalization and Flooding in China: A Chain Mediating by Ma, Anna, Yang, Yan, Guo, Shuangxi, Li, Xue, Zhang, Shenhua, Chang, Hongjuan

“…Natural disasters cause long-term psychological problems and increase substance use in some adults. However, it is unclear whether disasters also lead to these…”
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A Phase I Study of CUDC-101, a Multitarget Inhibitor of HDACs, EGFR, and HER2, in Combination with Chemoradiation in Patients with Head and Neck Squamous Cell Carcinoma by Galloway, Thomas J, Wirth, Lori J, Colevas, Alexander D, Gilbert, Jill, Bauman, Julie E, Saba, Nabil F, Raben, David, Mehra, Ranee, Ma, Anna W, Atoyan, Ruzanna, Wang, Jing, Burtness, Barbara, Jimeno, Antonio

“…CUDC-101 is a small molecule that simultaneously inhibits the epidermal growth factor receptor (EGFR), human growth factor receptor 2 (HER2), and histone…”
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Potential advantages of CUDC-101, a multitargeted HDAC, EGFR, and HER2 inhibitor, in treating drug resistance and preventing cancer cell migration and invasion by Wang, Jing, Pursell, Natalie W, Samson, Maria Elena S, Atoyan, Ruzanna, Ma, Anna W, Selmi, Abdelkader, Xu, Wanlu, Cai, Xiong, Voi, Maurizio, Savagner, Pierre, Lai, Cheng-Jung

“…CUDC-101 is a novel, small-molecule, anticancer agent targeting histone deacetylase (HDAC), EGF receptor (EGFR), and HER2. It is currently in phase I clinical…”
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Determinants of normal nutrition among 0–59-month-old Filipino children living in low-income households by Ramirez, Ma. Anna Rita, Ducay, Apple Joy

“…Background: An alternative concept in understanding malnutrition among 0 to 59-month-old children from low-income households is to look at and understand…”
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Multi-parent advanced generation inter-cross (MAGIC) populations in rice: progress and potential for genetics research and breeding by Bandillo, Nonoy, Raghavan, Chitra, Muyco, Pauline Andrea, Sevilla, Ma Anna Lynn, Lobina, Irish T, Dilla-Ermita, Christine Jade, Tung, Chih-Wei, McCouch, Susan, Thomson, Michael, Mauleon, Ramil, Singh, Rakesh Kumar, Gregorio, Glenn, Redoña, Edilberto, Leung, Hei

“…Background This article describes the development of Multi-parent Advanced Generation Inter-Cross populations (MAGIC) in rice and discusses potential…”
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Combining ability, floral biology, and seed producibility of promising cytoplasmic male-sterile (CMS) lines for hybrid rice development by Casco, Victoriano V., Tapic, Rosemarie T., Undan, Jerwin R., Latonio, Anna Ma. Lourdes S., Suralta, Roel R., Manigbas, Norvie L.

“…Abstract Background A combining ability analysis is a useful tool of plant breeders in screening and identifying promising parental lines with high potential…”
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Self-compassion and work engagement among Chinese nurses: exploring mediating effects of depression, anxiety, and stress by Yang, Yan, Chang, Hongjuan, Guo, Shuangxi, Gao, Xiao Lei, Wang, Lina, Ma, Anna

“…Work engagement significantly influences both the quality of nursing care and nurses' job performance. In this study, we aimed to explore the mediating effects…”
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Research progress on the antiviral activities of natural products and their derivatives: Structure–activity relationships by Guo, Yajing, Ma, Anna, Wang, Xinyan, Yang, Chen, Chen, Xi, Li, Gen, Qiu, Feng

“…Viruses spread rapidly and are well-adapted to changing environmental events. They can infect the human body readily and trigger fatal diseases. A limited…”
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Transforming growth factor β signaling upregulates the expression of human GDP-fucose transporter by activating transcription factor Sp1 by Xu, Yu-Xin, Ma, Anna, Liu, Li

“…GDP-fucose transporter plays a crucial role in fucosylation of glycoproteins by providing activated fucose donor, GDP-fucose, for fucosyltransferases in the…”
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Assessing school-lunch feeding and nutrition education strategy for healthier kids in selected Philippine public schools by Dorado, Julieta B, Azaña, Glenda P, Viajar, Rowena V, Ramirez, Ma. Anna Rita M, Ferrer, Eldridge B, Buyco, Nesrianne G, Aguila, Divorah V, Capanzana, Mario V

“…Background: Nutrition interventions during the early years of a child’s life are anchored on the need to provide good nutrition and proper health care to…”
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Adipose tissue glycogen accumulation is associated with obesity-linked inflammation in humans by Ceperuelo-Mallafré, Victòria, Ejarque, Miriam, Serena, Carolina, Duran, Xavier, Montori-Grau, Marta, Rodríguez, Miguel Angel, Yanes, Oscar, Núñez-Roa, Catalina, Roche, Kelly, Puthanveetil, Prasanth, Garrido-Sánchez, Lourdes, Saez, Enrique, Tinahones, Francisco J, Garcia-Roves, Pablo M, Gómez-Foix, Anna M, Saltiel, Alan R, Vendrell, Joan, Fernández-Veledo, Sonia

“…Abstract Objective Glycogen metabolism has emerged as a mediator in the control of energy homeostasis and studies in murine models reveal that adipose tissue…”
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Trends in the Prescription and Long-Term Utilization of Antidementia Drugs Among Patients with Alzheimer’s Disease in Spain: A Cohort Study Using the Registry of Dementias of Girona by Calvó-Perxas, Laia, Turró-Garriga, Oriol, Vilalta-Franch, Joan, Lozano-Gallego, Manuela, de Eugenio, Rosa, Márquez, Fabián, Carmona, Olga, Gich, Jordi, Manzano, Anna, Viñas, Marta, Roig, Anna Mª, Garre-Olmo, Josep

“…Background Acetylcholinesterase inhibitors (AChEIs) and the N -methyl d -aspartate-antagonist memantine are indicated for the symptomatic treatment of…”
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