Search Results - "MYLES, Dean A. A"

The in vivo structure of biological membranes and evidence for lipid domains by Nickels, Jonathan D, Chatterjee, Sneha, Stanley, Christopher B, Qian, Shuo, Cheng, Xiaolin, Myles, Dean A A, Standaert, Robert F, Elkins, James G, Katsaras, John

“…Examining the fundamental structure and processes of living cells at the nanoscale poses a unique analytical challenge, as cells are dynamic, chemically…”
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Description of Hydration Water in Protein (Green Fluorescent Protein) Solution by Perticaroli, Stefania, Ehlers, Georg, Stanley, Christopher B, Mamontov, Eugene, O’Neill, Hugh, Zhang, Qiu, Cheng, Xiaolin, Myles, Dean A. A, Katsaras, John, Nickels, Jonathan D

“…The structurally and dynamically perturbed hydration shells that surround proteins and biomolecules have a substantial influence upon their function and…”
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Mechanical Properties of Nanoscopic Lipid Domains by Nickels, Jonathan D, Cheng, Xiaolin, Mostofian, Barmak, Stanley, Christopher, Lindner, Benjamin, Heberle, Frederick A, Perticaroli, Stefania, Feygenson, Mikhail, Egami, Takeshi, Standaert, Robert F, Smith, Jeremy C, Myles, Dean A. A, Ohl, Michael, Katsaras, John

“…The lipid raft hypothesis presents insights into how the cell membrane organizes proteins and lipids to accomplish its many vital functions. Yet basic…”
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Mapping periplasmic binding protein oligosaccharide recognition with neutron crystallography by Shukla, Shantanu, Myles, Dean A., Cuneo, Matthew J.

“…Numerous studies have shown how periplasmic binding proteins (PBPs) bind substrates with exquisite specificity, even distinguishing between sugar epimers and…”
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Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition by Azadmanesh, Jahaun, Slobodnik, Katelyn, Struble, Lucas R., Lutz, William E., Coates, Leighton, Weiss, Kevin L., Myles, Dean A. A., Kroll, Thomas, Borgstahl, Gloria E. O.

“…Human manganese superoxide dismutase (MnSOD) is a crucial oxidoreductase that maintains the vitality of mitochondria by converting superoxide (O 2 ●− ) to…”
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Modulating Enzyme Activity by Altering Protein Dynamics with Solvent by Duff, Michael R, Borreguero, Jose M, Cuneo, Matthew J, Ramanathan, Arvind, He, Junhong, Kamath, Ganesh, Chennubhotla, S. Chakra, Meilleur, Flora, Howell, Elizabeth E, Herwig, Kenneth W, Myles, Dean A. A, Agarwal, Pratul K

“…Optimal enzyme activity depends on a number of factors, including structure and dynamics. The role of enzyme structure is well recognized; however, the linkage…”
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Differential Substrate Recognition by Maltose Binding Proteins Influenced by Structure and Dynamics by Shukla, Shantanu, Bafna, Khushboo, Gullett, Caeley, Myles, Dean A. A, Agarwal, Pratul K, Cuneo, Matthew J

“…The genome of the hyperthermophile Thermotoga maritima contains three isoforms of maltose binding protein (MBP) that are high-affinity receptors for di-, tri-,…”
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Breakdown of Cell Wall Nanostructure in Dilute Acid Pretreated Biomass by Pingali, Sai Venkatesh, Urban, Volker S, Heller, William T, McGaughey, Joseph, O’Neill, Hugh, Foston, Marcus, Myles, Dean A, Ragauskas, Arthur, Evans, Barbara R

“…The generation of bioethanol from lignocellulosic biomass holds great promise for renewable and clean energy production. A better understanding of the complex…”
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Bacillus subtilis Lipid Extract, A Branched-Chain Fatty Acid Model Membrane by Nickels, Jonathan D, Chatterjee, Sneha, Mostofian, Barmak, Stanley, Christopher B, Ohl, Michael, Zolnierczuk, Piotr, Schulz, Roland, Myles, Dean A. A, Standaert, Robert F, Elkins, James G, Cheng, Xiaolin, Katsaras, John

“…Lipid extracts are an excellent choice of model biomembrane; however at present, there are no commercially available lipid extracts or computational models…”
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The IMAGINE instrument: first neutron protein structure and new capabilities for neutron macromolecular crystallography by Meilleur, Flora, Munshi, Parthapratim, Robertson, Lee, Stoica, Alexandru D., Crow, Lowell, Kovalevsky, Andrey, Koritsanszky, Tibor, Chakoumakos, Bryan C., Blessing, Robert, Myles, Dean A. A.

“…The first high‐resolution neutron protein structure of perdeuterated rubredoxin from Pyrococcus furiosus (PfRd) determined using the new IMAGINE macromolecular…”
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The Bio-SANS instrument at the High Flux Isotope Reactor of Oak Ridge National Laboratory by Heller, William T., Urban, Volker S., Lynn, Gary W., Weiss, Kevin L., O'Neill, Hugh M., Pingali, Sai Venkatesh, Qian, Shuo, Littrell, Kenneth C., Melnichenko, Yuri B., Buchanan, Michelle V., Selby, Douglas L., Wignall, George D., Butler, Paul D., Myles, Dean A.

“…Small‐angle neutron scattering (SANS) is a powerful tool for characterizing complex disordered materials, including biological materials. The Bio‐SANS…”
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De novo design of a homo-trimeric amantadine-binding protein by Park, Jooyoung, Selvaraj, Brinda, McShan, Andrew C, Boyken, Scott E, Wei, Kathy Y, Oberdorfer, Gustav, DeGrado, William, Sgourakis, Nikolaos G, Cuneo, Matthew J, Myles, Dean Aa, Baker, David

“…The computational design of a symmetric protein homo-oligomer that binds a symmetry-matched small molecule larger than a metal ion has not yet been achieved…”
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IMAGINE: neutrons reveal enzyme chemistry by Schröder, Gabriela C., O'Dell, William B., Myles, Dean A. A., Kovalevsky, Andrey, Meilleur, Flora

“…Neutron diffraction is exquisitely sensitive to the positions of H atoms in protein crystal structures. IMAGINE is a high‐intensity, quasi‐Laue neutron…”
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Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature by Moreno-Chicano, Tadeo, Carey, Leiah M, Axford, Danny, Beale, John H, Doak, R Bruce, Duyvesteyn, Helen M E, Ebrahim, Ali, Henning, Robert W, Monteiro, Diana C F, Myles, Dean A, Owada, Shigeki, Sherrell, Darren A, Straw, Megan L, Šrajer, Vukica, Sugimoto, Hiroshi, Tono, Kensuke, Tosha, Takehiko, Tews, Ivo, Trebbin, Martin, Strange, Richard W, Weiss, Kevin L, Worrall, Jonathan A R, Meilleur, Flora, Owen, Robin L, Ghiladi, Reza A, Hough, Michael A

“…Room-temperature macromolecular crystallography allows protein structures to be determined under close-to-physiological conditions, permits dynamic freedom in…”
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The Structure of Sindbis Virus Produced from Vertebrate and Invertebrate Hosts as Determined by Small-Angle Neutron Scattering by LILIN HE, PIPER, Amanda, MEILLEUR, Flora, MYLES, Dean A. A, HERNANDEZ, Raquel, BROWN, Dennis T, HELLER, William T

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Scattering functions of Platonic solids by Li, Xin, Shew, Chwen-Yang, He, Lilin, Meilleur, Flora, Myles, Dean A. A., Liu, Emily, Zhang, Yang, Smith, Gregory S., Herwig, Kenneth W., Pynn, Roger, Chen, Wei-Ren

“…The single‐particle small‐angle scattering properties of five Platonic solids, including the tetrahedron, hexahedron, octahedron, dodecahedron and icosahedron,…”
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Impact of Fatty-Acid Labeling of Bacillus subtilis Membranes on the Cellular Lipidome and Proteome by Nickels, Jonathan D., Poudel, Suresh, Chatterjee, Sneha, Farmer, Abigail, Cordner, Destini, Campagna, Shawn R., Giannone, Richard J., Hettich, Robert L., Myles, Dean A. A., Standaert, Robert F., Katsaras, John, Elkins, James G.

“…Developing cultivation methods that yield chemically and isotopically defined fatty acid (FA) compositions within bacterial cytoplasmic membranes establishes…”
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The Neutron Macromolecular Crystallography Instruments at Oak Ridge National Laboratory: Advances, Challenges, and Opportunities by Meilleur, Flora, Coates, Leighton, Cuneo, Matthew, Kovalevsky, Andrey, Myles, Dean

“…The IMAGINE and MaNDi instruments, located at Oak Ridge National Laboratory High Flux Isotope Reactor and Spallation Neutron Source, respectively, are powerful…”
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Redox-Promoting Protein Motions in Rubredoxin by Borreguero, Jose M, He, Junhong, Meilleur, F, Weiss, Kevin L, Brown, Craig M, Myles, Dean A, Herwig, Kenneth W, Agarwal, Pratul K

“…Proteins are dynamic objects, constantly undergoing conformational fluctuations, yet the linkage between internal protein motion and function is widely…”
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SANS study of cellulose extracted from switchgrass by Pingali, Sai Venkatesh, Urban, Volker S., Heller, William T., McGaughey, Joseph, O'Neill, Hugh M., Foston, Marcus, Myles, Dean A., Ragauskas, Arthur J., Evans, Barbara R.

“…Lignocellulosic biomass, which is an abundant renewable natural resource, has the potential to play a major role in the generation of renewable biofuels…”
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