Search Results - "MYEONG HEE YU"

Demonstrating the feasibility of large-scale development of standardized assays to quantify human proteins by Kennedy, Jacob J, Abbatiello, Susan E, Kim, Kyunggon, Yan, Ping, Whiteaker, Jeffrey R, Lin, Chenwei, Kim, Jun Seok, Zhang, Yuzheng, Wang, Xianlong, Ivey, Richard G, Zhao, Lei, Min, Hophil, Lee, Youngju, Yu, Myeong-Hee, Yang, Eun Gyeong, Lee, Cheolju, Wang, Pei, Rodriguez, Henry, Kim, Youngsoo, Carr, Steven A, Paulovich, Amanda G

“…This Analysis reports the development and assessment of 645 multiple reaction monitoring (MRM) mass spectrometry assays to quantify 319 targeted human breast…”
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Identification of S100A8 and S100A9 as Serological Markers for Colorectal Cancer by Kim, Hye-Jung, Kang, Hyun Ju, Lee, Hanna, Lee, Seung-Taek, Yu, Myeong-Hee, Kim, Hoguen, Lee, Cheolju

“…In search of novel serological protein biomarkers for human colorectal cancer (CRC), we analyzed CRC tissues using two-dimensional difference in-gel…”
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Gcn4p-mediated transcriptional repression of ribosomal protein genes under amino-acid starvation by Joo, Yoo Jin, Kim, Jin-Ha, Kang, Un-Beom, Yu, Myeong-Hee, Kim, Joon

“…Gcn4p is a well‐characterized bZIP transcription factor that activates more than 500 genes encoding amino acids and purine biosynthesis enzymes, and many…”
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Differential profiling of breast cancer plasma proteome by isotope-coded affinity tagging method reveals biotinidase as a breast cancer biomarker by Kang, Un-Beom, Ahn, Younghee, Lee, Jong Won, Kim, Yong-Hak, Kim, Joon, Yu, Myeong-Hee, Noh, Dong-Young, Lee, Cheolju

“…Breast cancer is one of the leading causes of women's death worldwide. It is important to discover a reliable biomarker for the detection of breast cancer…”
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Autoantibody to Tumor Antigen, Alpha 2-HS Glycoprotein: A Novel Biomarker of Breast Cancer Screening and Diagnosis by JAE KYO YI, JONG WOOK CHANG, NOH, Dong-Young, HAN, Wonshik, JONG WON LEE, KO, Eunyoung, DONG HYUN KIM, BAE, Ji-Yeon, YU, Jonghan, LEE, Cheolju, YU, Myeong-Hee

“…We sought to identify a new serum biomarker for breast cancer screening and diagnosis using stepwise proteomic analysis of sera from breast cancer patients to…”
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Postexperiment Monoisotopic Mass Filtering and Refinement (PE-MMR) of Tandem Mass Spectrometric Data Increases Accuracy of Peptide Identification in LC/MS/MS by Shin, Byunghee, Jung, Hee-Jung, Hyung, Seok-Won, Kim, Hokeun, Lee, Dongkyu, Lee, Cheolju, Yu, Myeong-Hee, Lee, Sang-Won

“…Methods for treating MS/MS data to achieve accurate peptide identification are currently the subject of much research activity. In this study we describe a new…”
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Identification of circulating endorepellin LG3 fragment: Potential use as a serological biomarker for breast cancer by Chang, Jong Wook, Kang, Un-Beom, Kim, Dong Hyun, Yi, Jae Kyo, Lee, Jong Won, Noh, Dong-Young, Lee, Cheolju, Yu, Myeong-Hee

“…Comparative proteome analysis was performed on the cultured media of human nontumor and malignant breast cell lines, Hs578Bst and Hs578T, respectively, in…”
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2-Nitrobenzoate 2-Nitroreductase (NbaA) Switches Its Substrate Specificity from 2-Nitrobenzoic Acid to 2,4-Dinitrobenzoic Acid under Oxidizing Conditions by Kim, Yong-Hak, Song, Woo-Seok, Go, Hayoung, Cha, Chang-Jun, Lee, Cheolju, Yu, Myeong-Hee, Lau, Peter C K, Lee, Kangseok

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Rpn13p and Rpn14p are involved in the recognition of ubiquitinated Gcn4p by the 26S proteasome by Seong, Ki Moon, Baek, Je-Hyun, Yu, Myeong-Hee, Kim, Joon

“…The 26S proteasome, composed of the 20S core and 19S regulatory complexes, is important for the turnover of polyubiquitinated proteins. Each subunit of the…”
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A systems approach for decoding mitochondrial retrograde signaling pathways by Chae, Sehyun, Ahn, Byung Yong, Byun, Kyunghee, Cho, Young Min, Yu, Myeong-Hee, Lee, Bonghee, Hwang, Daehee, Park, Kyong Soo

“…Mitochondrial dysfunctions activate retrograde signaling from mitochondria to the nucleus. To identify transcription factors and their associated pathways that…”
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Proteomic analysis of stargazer mutant mouse neuronal proteins involved in absence seizure by Ryu, Myung-Jeom, Lee, Cheolju, Kim, Joon, Shin, Hee-Sup, Yu, Myeong-Hee

“…The stargazer (stg) mutant mouse, having mutation in stargazin, the calcium channel γ2 subunit, exhibited several neurological disorders including spontaneous…”
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proteomic approach based on multiple parallel separation for the unambiguous identification of an antibody cognate antigen by Mun, Joohee, Kim, Yong-Hak, Yu, Jonghan, Bae, Jinhee, Noh, Dong-Young, Yu, Myeong-Hee, Lee, Cheolju

“…Autoantibodies obtained from cancer patients have been identified as useful tools for cancer diagnostics, prognostics, and as potential targets for…”
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Novel β-structure of YLR301w from Saccharomyces cerevisiae by Kim, Kook-Han, Ahn, Hyung Jun, Lee, Won-Kyu, Lee, Cheolju, Yu, Myeong-Hee, Kim, Eunice EunKyeong

“…When the Z‐type variant of human α1‐antitrypsin was overexpressed in Saccharomyces cerevisiae, proteomics analysis identified YLR301w as one of the…”
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Network clustering revealed the systemic alterations of mitochondrial protein expression by Jeon, Jouhyun, Jeong, Jae Hoon, Baek, Je-Hyun, Koo, Hyun-Jung, Park, Wook-Ha, Yang, Jae-Seong, Yu, Myeong-Hee, Kim, Sanguk, Pak, Youngmi Kim

“…The mitochondrial protein repertoire varies depending on the cellular state. Protein component modifications caused by mitochondrial DNA (mtDNA) depletion are…”
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Novel Diagnostic Biomarkers for High-Grade Serous Ovarian Cancer Uncovered by Data-Independent Acquisition Mass Spectrometry by Huh, Sunghyun, Kang, Chaewon, Park, Ji Eun, Nam, Dowoon, Kim, Se Ik, Seol, Aeran, Choi, Kyerim, Hwang, Daehee, Yu, Myeong-Hee, Chung, Hyun Hoon, Lee, Sang-Won, Kang, Un-Beom

“…High-grade serous ovarian cancer (HGSOC) represents the major histological type of ovarian cancer, and the lack of effective screening tools and early…”
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Probing the local conformational change of α1‐antitrypsin by Baek, Je‐Hyun, Im, Hana, Kang, Un‐Beom, Seong, Ki Moon, Lee, Cheolju, Kim, Joon, Yu, Myeong‐Hee

“…The native form of serpins (serine protease inhibitors) is a metastable conformation, which converts into a more stable form upon complex formation with a…”
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Interactions Causing the Kinetic Trap in Serpin Protein Folding by Im, Hana, Woo, Mi-Sook, Hwang, Kwang Yeon, Yu, Myeong-Hee

“…Conformational transition is fundamental to the mechanism of functional regulation in proteins, and serpins (serine protease inhibitors) can provide insight…”
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Proteomic analysis of γ-butyrolactone-treated mouse thalamus reveals dysregulated proteins upon absence seizure by Ryu, Myung-Jeom, Kim, Daesoo, Kang, Un-Beom, Kim, Joon, Shin, Hee-Sup, Lee, Cheolju, Yu, Myeong-Hee

“…Absence seizure has been of interest because the symptom is related to sensory processing. However, the mechanism that causes the disease is not understood…”
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Regulation of Protein Function by Native Metastability by Lee, Cheolju, Park, Soon-Ho, Lee, Min-Youn, Yu, Myeong-Hee

“…In common globular proteins, the native form is in its most stable state. In contrast, each native form exists in a metastable state in inhibitory serpins…”
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Proteomic analysis of breast cancer tissue reveals upregulation of actin‐remodeling proteins and its relevance to cancer invasiveness by Kim, Dong‐Hyun, Bae, Jinhee, Lee, Jong Won, Kim, Seon‐Young, Kim, Yong‐Hak, Bae, Ji‐Yeon, Yi, Jae Kyo, Yu, Myeong‐Hee, Noh, Dong‐Young, Lee, Cheolju

“…There is an emerging interest in protein expression profiling with the aim of identifying novel diagnostic markers and therapeutic targets in breast cancer. We…”
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