Search Results - "MUTSCHLER, E"

Where in the brain is nonliteral language? A coordinate-based meta-analysis of functional magnetic resonance imaging studies by Rapp, Alexander M., Mutschler, Dorothee E., Erb, Michael

“…An increasing number of studies have investigated non-literal language, including metaphors, idioms, metonymy, or irony, with functional magnetic resonance…”
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Isn't it ironic? Neural correlates of irony comprehension in schizophrenia by Rapp, Alexander M, Langohr, Karin, Mutschler, Dorothee E, Klingberg, Stefan, Wild, Barbara, Erb, Michael

“…Ironic remarks are frequent in everyday language and represent an important form of social cognition. Increasing evidence indicates a deficit in comprehension…”
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Long-Term Outcome Following Liver Transplantation for Primary Hepatic Tumors-A Single Centre Observational Study over 40 Years by Leiskau, Christoph, Junge, Norman, Mutschler, Frauke E, Laue, Tobias, Ohlendorf, Johanna, Richter, Nicolas, Vondran, Florian W R, Pfister, Eva-Doreen, Baumann, Ulrich

“…The incidence of pediatric liver tumors in general has been rising over the last years and so is the number of children undergoing liver transplantation for…”
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Nonmyeloablative Stem Cell Therapy Enhances Microcirculation and Tissue Regeneration in Murine Inflammatory Bowel Disease by Khalil, Philipe N, Weiler, Véronique, Nelson, Peter J, Khalil, Maurice N, Moosmann, Sabine, Mutschler, Wolf E, Siebeck, Matthias, Huss, Ralf

“…Background & Aims: Reduced microcirculation has been implicated in the pathogenesis of inflammatory bowel disease (IBD). Stem cells or endothelial progenitor…”
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Neural correlates of irony comprehension: The role of schizotypal personality traits by Rapp, A.M., Mutschler, D.E., Wild, B., Erb, M., Lengsfeld, I., Saur, R., Grodd, W.

“…To detect that a conversational turn is intended to be ironic is a difficult challenge in everyday language comprehension. Most authors suggested a theory of…”
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Early down-regulation of the pro-inflammatory potential of monocytes is correlated to organ dysfunction in patients after severe multiple injury: a cohort study by Kirchhoff, Chlodwig, Biberthaler, Peter, Mutschler, Wolf E, Faist, Eugen, Jochum, Marianne, Zedler, Siegfried

“…Severe tissue trauma results in a general inflammatory immune response (SIRS) representing an overall inflammatory reaction of the immune system. However,…”
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Irony and Proverb Comprehension in Schizophrenia: Do Female Patients ＂Dislike＂ Ironic Remarks? by Wild, Barbara, Mutschler, Dorothee E., Langohr, Karin, Rapp, Alexander M.

“…Difficulties in understanding irony and sarcasm are part of the social cognition deficits in patients with schizophrenia. A number of studies have reported…”
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Antagonist binding profiles of five cloned human muscarinic receptor subtypes by Dörje, F, Wess, J, Lambrecht, G, Tacke, R, Mutschler, E, Brann, M R

“…A variety of muscarinic antagonists are currently used as tools to pharmacologically subclassify muscarinic receptors into M1, M2 and M3 subtypes. In the…”
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Surgical treatment of pelvic sarcomas: oncologic and functional outcome by Wirbel, R J, Schulte, M, Mutschler, W E

“…The experiences in treating 93 consecutive patients (56 males, 37 females; mean age, 38.5 years; range, 4-69 years), including 76 patients with primary…”
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Torasemide significantly reduces thiazide-induced potassium and magnesium loss despite supra-additive natriuresis by Knauf, H, Mutschler, E, Velazquez, H, Giebisch, G

“…Background Resistance to high-dose loop diuretics can be overcome either by co-administration with thiazides or by treatment with medium-dose loop diuretics…”
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Sequential Nephron Blockade Breaks Resistance to Diuretics in Edematous States by Knauf, H, Mutschler, E

“…Diuretic therapy in edematous diseases often yields an inadequate natriuretic response ("diuretic resistance"). To study the functional changes in patients…”
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Different binding affinities of NMDA receptor channel blockers in various brain regions—Indication of NMDA receptor heterogeneity by Bresink, I., Danysz, W., Parsons, C.G., Mutschler, E.

“…The N-methyl- d-aspartate (NMDA) receptor-channel complex exists in multiple forms which probably have different physiological and pharmacological properties…”
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Rate-limiting biotransformation of triamterene is mediated by CYP1A2 by Fuhr, U, Kober, S, Zaigler, M, Mutschler, E, Spahn-Langguth, H

“…Triamterene (TA), a potassium-sparing diuretic, is extensively metabolized by hydroxylation in 4'-position and subsequent conjugation by cytosolic…”
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The influence of cardiovascular and antiinflammatory drugs on thiazide-induced hemodynamic and saluretic effects by Knauf, H, Bailey, M A, Hasenfuss, G, Mutschler, E

“…Thiazide diuretics are known to induce a transient fall of the glomerular filtration rate (GFR), which, in turn, reduces tubular Na(+) load. This…”
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Functional role in ligand binding and receptor activation of an asparagine residue present in the sixth transmembrane domain of all muscarinic acetylcholine receptors by Blüml, K, Mutschler, E, Wess, J

“…The molecular mechanisms through which muscarinic receptors are activated upon binding of the neurotransmitter acetylcholine (ACh) are still poorly understood…”
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Diuretic effectiveness of hydrochlorothiazide and furosemide alone and in combination in chronic renal failure by Knauf, H, Mutschler, E

“…In the absence of formal clinical trials, the efficacy of thiazide diuretics in patients with renal impairment remains in doubt. Our study was therefore…”
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Renal handling of drugs in the healthy elderly : Creatinine clearance underestimates renal function and pharmacokinetics remain virtually unchanged by FLISER, D, BISCHOFF, I, HANSES, A, BLOCK, S, JOEST, M, RITZ, E, MUTSCHLER, E

“…It is commonly assumed that renal function, and in parallel the excretion of drugs, is considerably reduced in the elderly. Endogenous creatinine clearance or…”
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Pharmacology of intracellular cytosine-arabinoside-5'-triphosphate in malignant cells of pediatric patients with initial or relapsed leukemia and in normal lymphocytes by KOEHL, U, HOLLATZ, G, ROHRBACH, E, VISSCHEDYK, K, CINATL, J, KORNHUBER, B, KREUTER, J, MUTSCHLER, E, SCHWABE, D

“…The prodrug cytosinearabinoside (ara-C) is widely used in the treatment of acute leukemias. The active drug is the intracellular metabolite…”
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Vitamins C and E protect isolated cardiomyocytes against oxidative damage by Rinne, T, Mutschler, E, Wimmer-Greinecker, G, Moritz, A, Olbrich, H.G

“…There is considerable evidence that oxygen free radicals are involved in reperfusion injury of ischemic myocardium. Epidemiologic studies showed an inverse…”
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The influence of cardiovascular and antiinflammatory drugs on thiazide-induced hemodynamic and saluretic effects by KNAUF, H, BAILEY, M. A, HASENFUSS, G, MUTSCHLER, E

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