Search Results - "MUTASA, Kuda"
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Stunting is characterized by chronic inflammation in Zimbabwean infants
Published in PloS one (18-02-2014)“…Stunting affects one-third of children in developing countries, but the causes remain unclear. We hypothesized that enteropathy leads to low-grade…”
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Formative research on hygiene behaviors and geophagy among infants and young children and implications of exposure to fecal bacteria
Published in The American journal of tropical medicine and hygiene (01-10-2013)“…We conducted direct observation of 23 caregiver-infant pairs for 130 hours and recorded wash-related behaviors to identify pathways of fecal-oral transmission…”
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3
The gut microbiome and early-life growth in a population with high prevalence of stunting
Published in Nature communications (14-02-2023)“…Stunting affects one-in-five children globally and is associated with greater infectious morbidity, mortality and neurodevelopmental deficits. Recent evidence…”
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4
Inflammation and cytomegalovirus viremia during pregnancy drive sex-differentiated differences in mortality and immune development in HIV-exposed infants
Published in Nature communications (17-04-2024)“…Children who are HIV-exposed but uninfected have increased infectious mortality compared to HIV-unexposed children, raising the possibility of immune…”
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Malnutrition enteropathy in Zambian and Zimbabwean children with severe acute malnutrition: A multi-arm randomized phase II trial
Published in Nature communications (17-04-2024)“…Malnutrition underlies almost half of all child deaths globally. Severe Acute Malnutrition (SAM) carries unacceptable mortality, particularly if accompanied by…”
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The Impact of Improved Water, Sanitation, and Hygiene on Oral Rotavirus Vaccine Immunogenicity in Zimbabwean Infants: Substudy of a Cluster-randomized Trial
Published in Clinical infectious diseases (27-11-2019)“…Abstract Background Oral vaccines have lower efficacy in developing compared to developed countries. Poor water, sanitation, and hygiene (WASH) may contribute…”
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Effects of improved water, sanitation, and hygiene and improved complementary feeding on environmental enteric dysfunction in children in rural Zimbabwe: A cluster-randomized controlled trial
Published in PLoS neglected tropical diseases (01-02-2020)“…Environmental enteric dysfunction (EED) may be an important modifiable cause of child stunting. We described the evolution of EED biomarkers from birth to 18…”
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Child mortality according to maternal and infant HIV status in Zimbabwe
Published in The Pediatric infectious disease journal (01-06-2007)“…HIV causes substantial mortality among African children but there is limited data on how this is influenced by maternal or infant infection status and timing…”
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Stunting Status and Exposure to Infection and Inflammation in Early Life Shape Antibacterial Immune Cell Function Among Zimbabwean Children
Published in Frontiers in immunology (13-06-2022)“…Background Children who are stunted (length-for-age Z-score<-2) are at greater risk of infectious morbidity and mortality. Previous studies suggest that…”
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Maternal fecal microbiome predicts gestational age, birth weight and neonatal growth in rural Zimbabwe
Published in EBioMedicine (01-06-2021)“…Preterm birth and low birth weight (LBW) affect one in ten and one in seven livebirths, respectively, primarily in low-income and middle-income countries…”
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Assessing the Intestinal Microbiota in the SHINE Trial
Published in Clinical infectious diseases (15-12-2015)“…Advances in DNA sequencing technology now allow us to explore the dynamics and functions of the microbes that inhabit the human body, the microbiota. Recent…”
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Child Health, Agriculture and Integrated Nutrition (CHAIN): protocol for a randomised controlled trial of improved infant and young child feeding in rural Zimbabwe
Published in BMJ open (30-12-2022)“…Over one-quarter of children in sub-Saharan Africa are stunted; however, commercial supplements only partially meet child nutrient requirements, cannot be…”
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13
Congenital and postnatal CMV and EBV acquisition in HIV-infected Zimbabwean infants
Published in PloS one (18-12-2014)“…HIV-infected infants in sub-Saharan Africa have rapid disease progression. We hypothesized that co-infection with cytomegalovirus (CMV) or Epstein Barr virus…”
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Effects of improved complementary feeding and improved water, sanitation and hygiene on early child development among HIV-exposed children: substudy of a cluster randomised trial in rural Zimbabwe
Published in BMJ global health (01-01-2020)“…IntroductionHIV-exposed uninfected children may be at risk of poor neurodevelopment. We aimed to test the impact of improved infant and young child feeding…”
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Associations between biomarkers of environmental enteric dysfunction and oral rotavirus vaccine immunogenicity in rural Zimbabwean infants
Published in EClinicalMedicine (01-11-2021)“…Oral rotavirus vaccines (RVV) are poorly immunogenic in low-income countries. Environmental enteric dysfunction (EED) resulting from poor water, sanitation and…”
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16
Immune responses to oral poliovirus vaccine in HIV-exposed uninfected Zimbabwean infants
Published in Human vaccines & immunotherapeutics (02-11-2017)“…It remains uncertain whether HIV-exposed uninfected (HEU) infants have impaired responses to oral vaccines. We performed a cross-sectional study of 6-month-old…”
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Effects of infant sex on mother-to-child transmission of HIV-1 according to timing of infection in Zimbabwe
Published in AIDS (London) (03-10-2006)“…We examined the relationship between sex and the risk of intrauterine, intrapartum and postnatal HIV transmission among 4495 infants born to HIV-infected…”
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Impact of Water Quality, Sanitation, Handwashing, and Nutritional Interventions on Enteric Infections in Rural Zimbabwe: The Sanitation Hygiene Infant Nutrition Efficacy (SHINE) Trial
Published in The Journal of infectious diseases (28-03-2020)“…Abstract Background We assessed the impact of water, sanitation, and hygiene (WASH) and infant and young child feeding (IYCF) interventions on enteric…”
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Independent and combined effects of improved water, sanitation, and hygiene, and improved complementary feeding, on child stunting and anaemia in rural Zimbabwe: a cluster-randomised trial
Published in The Lancet global health (01-01-2019)“…Child stunting reduces survival and impairs neurodevelopment. We tested the independent and combined effects of improved water, sanitation, and hygiene (WASH),…”
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Risk factors for postdischarge mortality following hospitalization for severe acute malnutrition in Zimbabwe and Zambia
Published in The American journal of clinical nutrition (01-03-2021)“…Children discharged from hospital following management of complicated severe acute malnutrition (SAM) have a high risk of mortality, especially HIV-positive…”
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