Search Results - "MUSSER, Siegfried M."

Deciphering the Structure and Function of Nuclear Pores Using Single-Molecule Fluorescence Approaches by Musser, Siegfried M., Grünwald, David

“…Due to its central role in macromolecular trafficking and nucleocytoplasmic information transfer, the nuclear pore complex (NPC) has been studied in great…”
Get full text

Influence of the TorD signal peptide chaperone on Tat-dependent protein translocation by Bageshwar, Umesh K, DattaGupta, Antara, Musser, Siegfried M

“…The twin-arginine translocation (Tat) pathway transports folded proteins across energetic membranes. Numerous Tat substrates contain co-factors that are…”
Get full text

Oligomerization state of the functional bacterial twin-arginine translocation (Tat) receptor complex by Sharma, Ankith, Chowdhury, Rajdeep, Musser, Siegfried M.

“…The twin-arginine translocation (Tat) system transports folded proteins across bacterial and plastid energy transducing membranes. Ion leaks are generally…”
Get full text

Imaging of Single-Molecule Translocation through Nuclear Pore Complexes by Yang, Weidong, Gelles, Jeff, Musser, Siegfried M., Rosbash, Michael

“…Nuclear pore complexes (NPCs) mediate bidirectional transport of proteins, RNAs, and ribonucleoprotein complexes across the double-membrane nuclear envelope…”
Get full text

Choreography of importin-α/CAS complex assembly and disassembly at nuclear pores by Sun, Changxia, Fu, Guo, Ciziene, Danguole, Stewart, Murray, Musser, Siegfried M

“…Nuclear pore complexes (NPCs) mediate the exchange of macromolecules between the cytoplasm and the nucleoplasm. Soluble nuclear transport receptors bind…”
Get full text

Two Electrical Potential-Dependent Steps Are Required for Transport by the Escherichia coli Tat Machinery by Bageshwar, Umesh K., Musser, Siegfried M.

“…The twin-arginine translocation (Tat) pathway in Escherichia coli transports fully folded and assembled proteins across the energy-transducing periplasmic…”
Get full text

High Throughput Screen for Escherichia coli Twin Arginine Translocation (Tat) Inhibitors by Bageshwar, Umesh K, VerPlank, Lynn, Baker, Dwight, Dong, Wen, Hamsanathan, Shruthi, Whitaker, Neal, Sacchettini, James C, Musser, Siegfried M

“…The twin arginine translocation (Tat) pathway transports fully-folded and assembled proteins in bacteria, archaea and plant thylakoids. The Tat pathway…”
Get full text

Investigating molecular crowding within nuclear pores using polarization-PALM by Fu, Guo, Tu, Li-Chun, Zilman, Anton, Musser, Siegfried M

“…The key component of the nuclear pore complex (NPC) controlling permeability, selectivity, and the speed of nucleocytoplasmic transport is an assembly of…”
Get full text

Effect of Average Phospholipid Curvature on Supported Bilayer Formation on Glass by Vesicle Fusion by Hamai, Chiho, Yang, Tinglu, Kataoka, Sho, Cremer, Paul S., Musser, Siegfried M.

“…The adsorption of large unilamellar vesicles composed of various combinations of phosphatidylcholine, phosphatidylethanolamine (PE), monomethyl PE, and…”
Get full text

Single-molecule measurements of importin α/cargo complex dissociation at the nuclear pore by Sun, Changxia, Yang, Weidong, Tu, Li-Chun, Musser, Siegfried M

“…Macromolecules are transported between the cytoplasm and the nucleoplasm of eukaryotic cells through nuclear pore complexes (NPCs). Large (more than [almost…”
Get full text

Super-resolved 3D tracking of cargo transport through nuclear pore complexes by Chowdhury, Rajdeep, Sau, Abhishek, Musser, Siegfried M.

“…Nuclear pore complexes (NPCs) embedded within the nuclear envelope mediate rapid, selective and bidirectional traffic between the cytoplasm and the…”
Get full text

The Tat protein transport system: intriguing questions and conundrums by Hamsanathan, Shruthi, Musser, Siegfried M

“…The Tat machinery catalyzes the transport of folded proteins across the cytoplasmic membrane in bacteria and the thylakoid membrane in plants. Transport occurs…”
Get full text

Author Correction: Super-resolved 3D tracking of cargo transport through nuclear pore complexes by Chowdhury, Rajdeep, Sau, Abhishek, Musser, Siegfried M.

Get full text

Large cargo transport by nuclear pores: implications for the spatial organization of FG-nucleoporins by Tu, Li-Chun, Fu, Guo, Zilman, Anton, Musser, Siegfried M

“…Nuclear pore complexes (NPCs) mediate cargo traffic between the nucleus and the cytoplasm of eukaryotic cells. Nuclear transport receptors (NTRs) carry cargos…”
Get full text

Nuclear import time and transport efficiency depend on importin β concentration by Yang, Weidong, Musser, Siegfried M

“…Although many components and reaction steps necessary for bidirectional transport across the nuclear envelope (NE) have been characterized, the mechanism and…”
Get full text

A Hinged Signal Peptide Hairpin Enables Tat-Dependent Protein Translocation by Hamsanathan, Shruthi, Anthonymuthu, Tamil S., Bageshwar, Umesh K., Musser, Siegfried M.

“…The Tat machinery catalyzes the transport of folded proteins across the bacterial cytoplasmic membrane and the thylakoid membrane in plants. Using fluorescence…”
Get full text

Single Giant Vesicle Rupture Events Reveal Multiple Mechanisms of Glass-Supported Bilayer Formation by Hamai, Chiho, Cremer, Paul S., Musser, Siegfried M.

“…The formation of supported lipid bilayers (SLBs) on glass from giant unilamellar vesicles (GUVs) was studied using fluorescence microscopy. We show that GUV…”
Get full text

Kinetics of Precursor Interactions with the Bacterial Tat Translocase Detected by Real-time FRET by Whitaker, Neal, Bageshwar, Umesh K., Musser, Siegfried M.

“…The Escherichia coli twin-arginine translocation (Tat) system transports fully folded and assembled proteins across the inner membrane into the periplasmic…”
Get full text

Effect of cargo size and shape on the transport efficiency of the bacterial Tat translocase by Whitaker, Neal, Bageshwar, Umesh, Musser, Siegfried M.

“…► Seventeen modified pre-SufI cargos were tested for Tat translocation. ► Cargo size and shape significantly influenced Tat transport efficiency. ► Smaller…”
Get full text

Single molecule studies of nucleocytoplasmic transport by Tu, Li-Chun, Musser, Siegfried M.

“…Molecular traffic between the cytoplasm and the nucleoplasm of eukaryotic cells is mediated by nuclear pore complexes (NPCs). Hundreds, if not thousands, of…”
Get full text