Search Results - "MURTHY, R KRISHNA"

A computational method to aid the design and analysis of single cell RNA-seq experiments for cell type identification by Abrams, Douglas, Kumar, Parveen, Karuturi, R Krishna Murthy, George, Joshy

“…The advent of single cell RNA sequencing (scRNA-seq) enabled researchers to study transcriptomic activity within individual cells and identify inherent cell…”
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Multiple sclerosis-associated uveitis - A series from South India by Babu, Kalpana, Janardhana, Geethanjali C, Murthy, Krishna R

“…To report clinical profiles of multiple sclerosis (MS)-associated uveitis in seven cases from a single tertiary eye care center in South India. Retrospective…”
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The tandem duplicator phenotype as a distinct genomic configuration in cancer by Menghi, Francesca, Inaki, Koichiro, Woo, XingYi, Kumar, Pooja A., Grzeda, Krzysztof R., Malhotra, Ankit, Yadav, Vinod, Kim, Hyunsoo, Marquez, Eladio J., Ucar, Duygu, Shreckengast, Phung T., Wagner, Joel P., MacIntyre, George, Karuturi, Krishna R. Murthy, Scully, Ralph, Keck, James, Chuang, Jeffrey H., Liu, Edison T.

“…Next-generation sequencing studies have revealed genome-wide structural variation patterns in cancer, such as chromothripsis and chromoplexy, that do not…”
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Transcriptomic analyses of sexual dimorphism of the zebrafish liver and the effect of sex hormones by Zheng, Weiling, Xu, Hongyan, Lam, Siew Hong, Luo, Huaien, Karuturi, R Krishna Murthy, Gong, Zhiyuan

“…The liver is one of the most sex-dimorphic organs in both oviparous and viviparous animals. In order to understand the molecular basis of the difference…”
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CUP-AI-Dx: A tool for inferring cancer tissue of origin and molecular subtype using RNA gene-expression data and artificial intelligence by Zhao, Yue, Pan, Ziwei, Namburi, Sandeep, Pattison, Andrew, Posner, Atara, Balachander, Shiva, Paisie, Carolyn A., Reddi, Honey V, Rueter, Jens, Gill, Anthony J, Fox, Stephen, Raghav, Kanwal P.S., Flynn, William F, Tothill, Richard W., Li, Sheng, Karuturi, R. Krishna Murthy, George, Joshy

“…Cancer of unknown primary (CUP), representing approximately 3-5% of all malignancies, is defined as metastatic cancer where a primary site of origin cannot be…”
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Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): challenges and guidelines by Woo, Xing Yi, Srivastava, Anuj, Graber, Joel H, Yadav, Vinod, Sarsani, Vishal Kumar, Simons, Al, Beane, Glen, Grubb, Stephen, Ananda, Guruprasad, Liu, Rangjiao, Stafford, Grace, Chuang, Jeffrey H, Airhart, Susan D, Karuturi, R Krishna Murthy, George, Joshy, Bult, Carol J

“…Patient-derived xenograft (PDX) models are in vivo models of human cancer that have been used for translational cancer research and therapy selection for…”
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REST regulates distinct transcriptional networks in embryonic and neural stem cells by Johnson, Rory, Teh, Christina Hui-leng, Kunarso, Galih, Wong, Kee Yew, Srinivasan, Gopalan, Cooper, Megan L, Volta, Manuela, Chan, Sarah Su-ling, Lipovich, Leonard, Pollard, Steven M, Karuturi, R Krishna Murthy, Wei, Chia-lin, Buckley, Noel J, Stanton, Lawrence W

“…The maintenance of pluripotency and specification of cellular lineages during embryonic development are controlled by transcriptional regulatory networks,…”
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Adaptive Sentinel Testing in Workplace for COVID-19 Pandemic by Li, Yi, Chen, Mandy, George, Joshy, Liu, Edison T, Karuturi, R Krishna Murthy

“…Testing and isolation of infectious employees is one of the critical strategies to make the workplace safe during the pandemic for many organizations. Adaptive…”
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MultiDCoX: Multi-factor analysis of differential co-expression by Liany, Herty, Rajapakse, Jagath C, Karuturi, R Krishna Murthy

“…Differential co-expression (DCX) signifies change in degree of co-expression of a set of genes among different biological conditions. It has been used to…”
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What Makes Cornea Immunologically Unique and Privileged? Mechanistic Clues from a High-Resolution Proteomic Landscape of the Human Cornea by Subbannayya, Yashwanth, Pinto, Sneha M, Mohanty, Varshasnata, Dagamajalu, Shobha, Prasad, Thottethodi Subrahmanya Keshava, Murthy, Krishna R

“…Success rates of corneal transplantation are particularly high owing to its unique, innate immune privilege derived from a phenomenon known as Anterior…”
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High-resolution deconstruction of evolution induced by chemotherapy treatments in breast cancer xenografts by Kim, Hyunsoo, Kumar, Pooja, Menghi, Francesca, Noorbakhsh, Javad, Cerveira, Eliza, Ryan, Mallory, Zhu, Qihui, Ananda, Guruprasad, George, Joshy, Chen, Henry C., Mockus, Susan, Zhang, Chengsheng, Yang, Yan, Keck, James, Karuturi, R. Krishna Murthy, Bult, Carol J., Lee, Charles, Liu, Edison T., Chuang, Jeffrey H.

“…The processes by which tumors evolve are essential to the efficacy of treatment, but quantitative understanding of intratumoral dynamics has been limited…”
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Near full thickness macular hole with an intact overlying internal limiting membrane following resolution of fulminant acquired toxoplasma retinitis -A unique finding by Babu, Kalpana, Shah, Dhwani, Bhagya, M, Murthy, Krishna

“…A 43-year-old immunocompetent male presented with focal macular retinitis with overlying vitritis in the right eye. His BCVA was counting fingers close to…”
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Uveitis, retinal vasculitis, and loss of accommodation as sole manifestations of demyelinating disease: A case report by Babu, Kalpana, Murthy, Gowri, Murthy, Krishna

“…In this report we describe nongranulomatous uveitis followed by bilateral retinal vasculitis and much later by the loss of accommodation as initial…”
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Seroprevalence of Lymes disease in the Nagarahole and Bandipur forest areas of South India by Babu, Kalpana, Murthy, Krishna, Bhagya, M, Murthy, Praveen, Puttamallesh, Vinuth, Ravi, V

“…Purpose: The aim of this study was to determine the seroprevalence of Lymes disease in a population at risk in south India. Methods: Prospective ongoing study…”
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Cold abscess of dental origin in a 7-year-old child by Ganesh, Mayuri, Priya, V, Banu, M, Shilpa, G, Challa, Santosh, R Krishna Murthy, V

“…Abscess related to an infected tooth is mostly associated with pyogenic infection, but sometimes, it can be asymptomatic and indicate a chronic condition. This…”
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Transfer learning‐trained convolutional neural networks identify novel MRI biomarkers of Alzheimer's disease progression by Li, Yi, Haber, Annat, Preuss, Christoph, John, Cai, Uyar, Asli, Yang, Hongtian Stanley, Logsdon, Benjamin A., Philip, Vivek, Karuturi, R. Krishna Murthy, Carter, Gregory W.

“…Introduction Genome‐wide association studies (GWAS) for late onset Alzheimer's disease (AD) may miss genetic variants relevant for delineating disease stages…”
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Zebrafish whole-adult-organism chemogenomics for large-scale predictive and discovery chemical biology by Lam, Siew Hong, Mathavan, Sinnakarupan, Tong, Yan, Li, Haixia, Karuturi, R Krishna Murthy, Wu, Yilian, Vega, Vinsensius B, Liu, Edison T, Gong, Zhiyuan

“…The ability to perform large-scale, expression-based chemogenomics on whole adult organisms, as in invertebrate models (worm and fly), is highly desirable for…”
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Bilateral arterial occlusions masking retinitis in a HIV-positive male by Babu, Kalpana, Sudheer, Bhagya, Murthy, Krishna

“…We report an interesting case of 36-year-old HIV-positive male with uveitis, cilioretinal artery occlusion in OD, and superotemporal branch retinal artery…”
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Progressive, subretinal fibrosis mimicking retinal necrosis with poor visual prognosis in sympathetic ophthalmia: A rare finding by Babu, Kalpana, Jidesh, Megha, Sudheer, Bhagya, Murthy, Krishna

“…We report a rare finding of progressive subretinal fibrosis mimicking retinal necrosis in 2 cases of sympathetic ophthalmia. Histopathology of the inciting eye…”
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Infectious laryngotracheitis: Etiology, epidemiology, pathobiology, and advances in diagnosis and control - a comprehensive review by Gowthaman, Vasudevan, Kumar, Sachin, Koul, Monika, Dave, Urmil, Murthy, T. R. Gopala Krishna, Munuswamy, Palanivelu, Tiwari, Ruchi, Karthik, Kumaragurubaran, Dhama, Kuldeep, Michalak, Izabela, Joshi, Sunil K.

“…Infectious laryngotracheitis (ILT) is a highly contagious upper respiratory tract disease of chicken caused by a Gallid herpesvirus 1 (GaHV-1) belonging to the…”
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