Search Results - "MURRAY, Samuel S"

Bone morphogenetic protein-2 and tumor growth: Diverse effects and possibilities for therapy by Tian, Haijun, Zhao, Jie, Brochmann, Elsa J, Wang, Jeffrey C, Murray, Samuel S

“…Graphical abstract…”
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BMP induced inflammation: A comparison of rhBMP-7 and rhBMP-2 by Lee, Kwang-Bok, Taghavi, Cyrus E., Murray, Samuel S., Song, Kyung-Jin, Keorochana, Gun, Wang, Jeffrey C.

“…Concern has been raised because of reports of inflammatory swelling following the use of recombinant human bone morphogenetic protein‐2 (rhBMP‐2) and…”
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The Adjunctive Effect of a Binding Peptide on Bone Morphogenetic Protein Enhanced Bone Healing in a Rodent Model of Spinal Fusion by ALANAY, Ahmet, CHIHUI CHEN, LEE, Sang, MURRAY, Samuel S, BROCHMANN, Elsa J, MIYAZAKI, Masashi, NAPOLI, Antonia, WANG, Jeffrey C

“…A prospective 8-week interventional trial employing a rat model of spinal fusion to test the effect on bone morphogenetic protein binding peptide (BBP) on…”
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Secreted phosphoprotein 24 kD (Spp24) and Spp14 affect TGF-β induced bone formation differently by Tian, Haijun, Bi, Xiaoda, Li, Chen-Shuang, Zhao, Ke-Wei, Brochmann, Elsa J, Montgomery, Scott R, Aghdasi, Bayan, Chen, Deyu, Daubs, Michael D, Wang, Jeffrey C, Murray, Samuel S

“…Transforming growth factor-β (TGF-β) and bone morphogenetic proteins (BMPs) have opposing but complementary functions in directing bone growth, repair, and…”
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Bone Morphogenetic Protein Binding Peptide Mechanism and Enhancement of Osteogenic Protein-1 Induced Bone Healing by TAGHAVI, Cyrus E, LEE, Kwang-Bok, WUBING HE, KEOROCHANA, Gun, MURRAY, Samuel S, BROCHMANN, Elsa J, ULUDAG, Hasan, BEHNAM, Keyvan, WANG, Jeffrey C

“…In vitro and in vivo evaluation of BBP interactions with BMP. To explore bone morphogenetic protein-binding peptide (BBP)'s mechanism of action, investigate an…”
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Bone morphogenetic protein–binding peptide reduces the inflammatory response to recombinant human bone morphogenetic protein-2 and recombinant human bone morphogenetic protein-7 in a rodent model of soft-tissue inflammation by Lee, Kwang-Bok, MD, PhD, Murray, Samuel S., MD, Taghavi, Cyrus E., MD, Song, Kyung-Jin, MD, Brochmann, Elsa J., PhD, Johnson, Jared S., MD, Keorochana, Gun, MD, Liao, Jen-Chung, MD, Wang, Jeffrey C., MD

“…Abstract Background context Bone morphogenetic protein (BMP)-2 and BMP-7 are used to enhance bone formation in spine surgery, but the use of these materials is…”
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Secreted phosphoprotein 24 kD inhibits nerve root inflammation induced by bone morphogenetic protein-2 by Tian, Haijun, MD, PhD, Li, Chen-Shuang, DDS, Scott, Trevor P., MD, Montgomery, Scott R., MD, Phan, Kevin, BS, Lao, Lifeng, MD, PhD, Zhang, Wei, MD, PhD, Li, Yawei, MD, PhD, Hayashi, Tetsuo, MD, Takahashi, Shinji, MD, Alobaidaan, Raed, MD, Ruangchainikom, Monchai, MD, Zhao, Ke-Wei, PhD, Brochmann, Elsa J., PhD, Murray, Samuel S., MD, Wang, Jeffrey C., MD, Daubs, Michael D., MD

“…Abstract Background context Bone morphogenetic protein-2 (BMP-2) has been used to successfully promote spine fusion, but side-effects including nerve…”
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Adequate Restoration of Disc Height and Segmental Lordosis by Lumbar Interbody Fusion Decreases Adjacent Segment Degeneration by Tian, Haijun, Wu, Aimin, Guo, Mingke, Zhang, Kai, Chen, Chen, Li, Xunlin, Cheng, Xiaofei, Zhou, Tangjun, Murray, Samuel S., Sun, Xiaojiang, Zhao, Jie

“…This study aimed to investigate the effects of lumbar interbody fusion–induced biomechanical changes on the adjacent segments, especially disc height and…”
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Bone morphogenetic protein‐2 promotes osteosarcoma growth by promoting epithelial‐mesenchymal transition (EMT) through the Wnt/β‐catenin signaling pathway by Tian, Haijun, Zhou, Tangjun, Chen, Hongfang, Li, Chenshuang, Jiang, Ziyue, Lao, Lifeng, Kahn, Suzana Assad, Duarte, Maria Eugenia Leite, Zhao, Jie, Daubs, Michael D., Buser, Zorica, Brochmann, Elsa J., Wang, Jeffrey C., Murray, Samuel S.

“…ABSTRACT The correlation between BMP‐2 and osteosarcoma growth has gained increased interest in the recent years, however, there is still no consensus. In this…”
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Secreted phosphoprotein 24 kD (Spp24) inhibits the growth of human osteosarcoma through the BMP‐2/Smad signaling pathway by Chen, Hongfang, Li, Chenshuang, Zhou, Tangjun, Li, Xunlin, Duarte, Maria Eugenia L., Daubs, Michael D., Buser, Zorica, Brochmann, Elsa J., Wang, Jeffrey C., Murray, Samuel S., Jiao, Li, Tian, Haijun

“…Autocrine stimulation of tumor cells is an important mechanism for the growth of skeletal tumors. In tumors that are sensitive, growth factor inhibitors can…”
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Growth-Factor Nanocapsules That Enable Tunable Controlled Release for Bone Regeneration by Tian, Haijun, Du, Juanjuan, Wen, Jing, Liu, Yang, Montgomery, Scott R, Scott, Trevor P, Aghdasi, Bayan, Xiong, Chengjie, Suzuki, Akinobu, Hayashi, Tetsuo, Ruangchainikom, Monchai, Phan, Kevin, Weintraub, Gil, Raed, Alobaidaan, Murray, Samuel S, Daubs, Michael D, Yang, Xianjin, Yuan, Xu-bo, Wang, Jeffrey C, Lu, Yunfeng

“…Growth factors are of great potential in regenerative medicine. However, their clinical applications are largely limited by the short in vivo half-lives and…”
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Secreted Phosphoprotein 24 kD Inhibits Growth of Human Prostate Cancer Cells Stimulated by BMP-2 by Lao, Lifeng, Shen, Jia, Tian, Haijun, Yao, Qingqiang, Li, Yawei, Qian, Lie, Murray, Samuel S, Wang, Jeffrey C

“…Secreted phosphoprotein 24 kD (spp24) has been shown to inhibit bone morphogenetic protein 2 (BMP2)-induced cancer growth in several tumor models. In this…”
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HK2 Proximal Tubule Epithelial Cells Synthesize and Secrete Plasma Proteins Predominantly Through the Apical Surface by Zhao, Ke‐Wei, Murray, Elsa J. Brochmann, Murray, Samuel S.

“…ABSTRACT Renal proximal tubule epithelial cells (PTECs) are known to reabsorb salts and small plasma proteins filtered through Bowman's capsule. Following…”
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Secreted phosphoprotein 24 kD (Spp24) inhibits growth of hepatocellular carcinoma in vivo by Lao, Lifeng, Shen, Jia, Tian, Haijun, Zhong, Guibin, Murray, Samuel S, Wang, Jeffrey C

“…Highlights • Secreted phosphoprotein 24 kD inhibits hepatocellular carcinoma growth. • Secreted phosphoprotein 24 kD promote hepatocellular carcinoma cell…”
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Alanine-scanning mutations of the BMP-binding domain of recombinant secretory bovine spp24 affect cytokine binding by Sun, Argus, Murray, Samuel S, Simon, Robert J, Jawien, Janusz, Behnam, Keyvan, Miller, Timothy A, Brochmann, Elsa J

“…Secreted phosphoprotein 24 kDa (spp24) is a bone morphogenetic protein (BMP)/transforming growth factor-β cytokine-binding protein. The spp24…”
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Recombinant Expression, Isolation, and Proteolysis of Extracellular Matrix-Secreted Phosphoprotein-24 kDa by Brochmann Murray, Elsa J., Murray, Samuel S., Simon, Robert, Behnam, Keyvan

“…Secreted phosphoprotein-24 kDa (spp24) is an extracellular matrix protein first cloned from bone. Bovine spp24 is transcribed as a 203 amino acid residue…”
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Absence of bone morphogenetic protein-2 in human breast milk after spinal surgery by Tzeng, Shiau-Tzu, MD, Liao, Jen-Chung, MD, Murray, Samuel S., MD, Brochmann, Elsa J., PhD, Carlson, Gregory D., MD, Wang, Jeffrey C., MD

“…Abstract Background Context Bone morphogenetic protein-2 (BMP-2) has been used extensively in recent years to enhance the process of spinal fusion. However,…”
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The history and histology of bone morphogenetic protein by Murray, Samuel S, Brochmann Murray, Elsa J, Wang, Jeffrey C, Duarte, Maria Eugenia Leite

“…Bone morphogenetic proteins are a group of structurally related proteins within the TGF-β superfamily of proteins with a diverse repertoire of functions in…”
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An association between successful engraftment of osteosarcoma patient-derived xenografts and clinicopathological findings by Fortuna-Costa, Anneliese, Granato, Regina Alcantara, Meohas, Walter, Lopes, Ana Cristina de Sá, Caruso, Anabela Cunha, Castro E Silva Pinheiro, Rafael, d'Eça, Pedro da Gama, Dias, Rhayra Braga, Perini, Jamila Alessandra, Barbosa, Ana Paula Fernandes, Moreira de Sá, Renato Augusto, Guimarães, João Antonio Matheus, Murray, Samuel S, Duarte, Maria Eugenia Leite

“…Although osteosarcoma is a rare disease, with a global incidence rate estimated at 5.0/million/year, it is the most frequent primary bone sarcoma in children…”
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Spp24 Derivatives Stimulate a Gi-Protein Coupled Receptor-Erk1/2 Signaling Pathway and Modulate Gene Expressions in W-20-17 Cells by Zhao, Ke-Wei, Brochmann Murray, Elsa J., Murray, Samuel S.

“…ABSTRACT Secreted phosphoprotein 24 kDa (Spp24) is an apatite‐ and BMP/TGF‐β cytokine‐binding phosphoprotein found in serum and many tissues, including bone…”
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