Search Results - "MURRAY, F. T"
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1
TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine
Published in Nature communications (20-09-2017)“…CD103 + CD11b + dendritic cells (DCs) are unique to the intestine, but the factors governing their differentiation are unclear. Here we show that transforming…”
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2
Pioglitazone preserves pancreatic islet structure and insulin secretory function in three murine models of type 2 diabetes
Published in American journal of physiology: endocrinology and metabolism (01-01-2004)“…Thiazolidinediones may slow the progression of type 2 diabetes by preserving pancreatic beta-cells. The effects of pioglitazone (PIO) on structure and function…”
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3
Effects of high-intensity resistance training on untrained older men. I. Strength, cardiovascular, and metabolic responses
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-07-2000)“…Most resistance training studies of older subjects have emphasized low-intensity, short-term training programs that have concentrated on strength measurements…”
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4
The neurotoxic lipopeptide kalkitoxin interacts with voltage-sensitive sodium channels in cerebellar granule neurons
Published in Toxicology letters (14-08-2005)“…The marine neurotoxin kalkitoxin, a thiazoline-containing lipid derived from the pantropical marine cyanobacterium Lyngbya majuscula, was assayed for…”
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5
Gambierol acts as a functional antagonist of neurotoxin site 5 on voltage-gated sodium channels in cerebellar granule neurons
Published in The Journal of pharmacology and experimental therapeutics (01-10-2007)“…The marine toxin gambierol, a polyether ladder toxin derived from the marine dinoflagellate Gambierdiscus toxicus, was evaluated for interaction with…”
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6
Antillatoxin is a Marine Cyanobacterial Toxin That Potently Activates Voltage-Gated Sodium Channels
Published in Proceedings of the National Academy of Sciences - PNAS (19-06-2001)“…Antillatoxin (ATX) is a lipopeptide derived from the pantropical marine cyanobacterium Lyngbya majuscula. ATX is neurotoxic in primary cultures of rat…”
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7
Structure, Synthesis, and Biological Properties of Kalkitoxin, a Novel Neurotoxin from the Marine Cyanobacterium Lyngbya majuscula
Published in Journal of the American Chemical Society (06-12-2000)“…Cyanobacteria from a diversity of marine and freshwater habitats are known to produce neurotoxic secondary metabolites. Herein, we describe the complete…”
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8
Yohimbine treatment of organic erectile dysfunction in a dose-escalation trial
Published in International journal of impotence research (01-02-2002)“…Yohimbine has had questionable effects in men with organic erectile dysfunction. We conducted this study to better define the population of men responsive to…”
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9
Antillatoxin and kalkitoxin, ichthyotoxins from the tropical cyanobacterium Lyngbya majuscula, induce distinct temporal patterns of NMDA receptor-mediated neurotoxicity
Published in Toxicon (Oxford) (01-11-1999)“…Curacin-A, antillatoxin and kalkitoxin, natural products from the marine cyanobacterium Lyngbya majuscula, were tested for neurotoxicity in primary cultures of…”
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10
Characterization of the Preferred Stereochemistry for the Neuropharmacologic Actions of Antillatoxin
Published in Journal of natural products (Washington, D.C.) (01-04-2004)“…Antillatoxin is a potent ichthyotoxin and cytotoxin previously discovered from the marine cyanobacterium Lyngbya majuscula. Ensuing studies of its mechanism of…”
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11
Brevetoxin derivatives act as partial agonists at neurotoxin site 5 on the voltage-gated Na + channel
Published in Brain research (03-01-2003)“…Brevetoxins (PbTx-1 to PbTx-10) are potent lipid-soluble polyether neurotoxins produced by the marine dinoflagellate Karina brevis, an organism associated with…”
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12
Domoic Acid Neurotoxicity in Cultured Cerebellar Granule Neurons Is Mediated Predominantly by NMDA Receptors that Are Activated as a Consequence of Excitatory Amino Acid Release
Published in Journal of neurochemistry (01-08-1997)“…: The participation of NMDA and non‐NMDA receptors in domoic acid‐induced neurotoxicity was investigated in cultured rat cerebellar granule cells (CGCs)…”
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13
Characterization of [125I]ZM 241385 binding to adenosine A2A receptors in the pineal of sheep brain
Published in Brain research (22-06-2006)“…Adenosine is a ubiquitous neuromodulator and homeostatic regulator that exerts its physiologic actions through activation of A(1), A(2A), A(2B) and A(3)…”
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14
Behavioral, Pharmacological, and Molecular Characterization of an Amphibian Cannabinoid Receptor
Published in Journal of neurochemistry (01-07-2000)“…: Investigation of cannabinoid pharmacology in a vertebrate with a phylogenetic history distinct from that of mammals may allow better understanding of the…”
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15
Differential binding properties of [ 3H]dextrorphan and [ 3H]MK-801 in heterologously expressed NMDA receptors
Published in Neuropharmacology (01-07-2005)“…The N-methyl- d-aspartate receptor (NMDAR) antagonists: MK-801, phencyclidine and ketamine are open-channel blockers with limited clinical value due to…”
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16
Brevetoxin‐Induced Autocrine Excitotoxicity Is Associated with Manifold Routes of Ca2+ Influx
Published in Journal of neurochemistry (01-04-2000)“…: Real‐time alterations in intracellular Ca2+ ([Ca2+]i) were monitored in fluo‐3‐loaded cerebellar granule neurons (CGNs) exposed to the brevetoxin PbTx‐1…”
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17
A Corticosteroid Receptor in Neuronal Membranes
Published in Science (American Association for the Advancement of Science) (28-06-1991)“…Steroids may rapidly alter neuronal function and behavior through poorly characterized, direct actions on neuronal membranes. The membrane-bound receptors…”
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18
Alanine analogues of [D‐Trp]CJ‐15,208: novel opioid activity profiles and prevention of drug‐ and stress‐induced reinstatement of cocaine‐seeking behaviour
Published in British journal of pharmacology (01-07-2014)“…Background and Purpose The novel macrocyclic peptide cyclo[Phe‐D‐Pro‐Phe‐D‐Trp] ([D‐Trp]CJ‐15,208) exhibits κ opioid (KOP) receptor antagonist activity in both…”
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19
Partial purification and biochemical characterization of a membrane glucocorticoid receptor from an amphibian brain
Published in The Journal of steroid biochemistry and molecular biology (01-04-2000)“…A membrane receptor for corticosterone (mGR) in the brain of the roughskin newt ( Taricha granulosa) has been previously identified. This manuscript reports…”
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20
Manipulation of endogenous adenosine in the rat prepiriform cortex modulates seizure susceptibility
Published in The Journal of pharmacology and experimental therapeutics (01-03-1993)“…A1 adenosine receptors in the rat prepiriform cortex play an important role in the inhibition of bicuculline methiodide-induced convulsions. In the present…”
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