Search Results - "MURPHY, R. M"
-
1
Ca2+‐dependent proteolysis of junctophilin‐1 and junctophilin‐2 in skeletal and cardiac muscle
Published in The Journal of physiology (01-02-2013)“…Key points If skeletal muscle fibres are subjected to excessive activation, or stretched whilst contracting, they subsequently display long‐term reductions in…”
Get full text
Journal Article -
2
Effects of carnosine on contractile apparatus Ca²⁺ sensitivity and sarcoplasmic reticulum Ca²⁺ release in human skeletal muscle fibers
Published in Journal of applied physiology (1985) (01-03-2012)“…There is considerable interest in potential ergogenic and therapeutic effects of increasing skeletal muscle carnosine content, although its effects on…”
Get full text
Journal Article -
3
Acute effects of taurine on sarcoplasmic reticulum Ca2+ accumulation and contractility in human type I and type II skeletal muscle fibers
Published in Journal of applied physiology (1985) (01-10-2014)“…Taurine occurs in high concentrations in muscle and is implicated in numerous physiological processes, yet its effects on many aspects of contractility remain…”
Get full text
Journal Article -
4
Ca2+ leakage out of the sarcoplasmic reticulum is increased in type I skeletal muscle fibres in aged humans
Published in The Journal of physiology (15-01-2016)“…Key points The amount of Ca2+ stored in the sarcoplasmic reticulum (SR) of muscle fibres is decreased in aged individuals, and an important question is whether…”
Get full text
Journal Article -
5
Hydroxyl radical and glutathione interactions alter calcium sensitivity and maximum force of the contractile apparatus in rat skeletal muscle fibres
Published in The Journal of physiology (15-04-2008)“…Studies on intact muscle fibres indicate that reactive oxygen species (ROS) produced during muscle activity, or applied exogenously, can cause decreased force…”
Get full text
Journal Article -
6
Prepartum intake, postpartum induction of ketosis, and periparturient disorders affect the metabolic status of dairy cows
Published in Journal of dairy science (01-09-2005)“…Nutritional management during the dry period may affect susceptibility of cows to metabolic and infectious diseases during the periparturient period…”
Get more information
Journal Article -
7
Dietary cation-anion difference effects on performance and acid-base status of lactating dairy cows: a meta-analysis
Published in Journal of dairy science (01-07-2004)“…A meta-analysis was conducted to examine potential empirical relationships between dietary cation-anion difference (DCAD) (Na + K - Cl) and the response of…”
Get more information
Journal Article -
8
Increased FXYD1 and PGC‐1α mRNA after blood flow‐restricted running is related to fibre type‐specific AMPK signalling and oxidative stress in human muscle
Published in Acta Physiologica (01-06-2018)“…Aim This study explored the effects of blood flow restriction (BFR) on mRNA responses of PGC‐1α (total, 1α1, and 1α4) and Na+,K+‐ATPase isoforms (NKA; α1‐3,…”
Get full text
Journal Article -
9
Dietary cation-anion difference and dietary protein effects on performance and acid-base status of dairy cows in early lactation
Published in Journal of dairy science (01-07-2007)“…Our objective was to examine the effects of dietary cation-anion difference (DCAD) with different concentrations of dietary crude protein (CP) on performance…”
Get more information
Journal Article -
10
Nitrogen transactions along the gastrointestinal tract of cattle: A meta-analytical approach
Published in Journal of animal science (01-03-2008)“…In ruminant animals, endogenous N (EN) secretions contribute to meeting the N requirement of the ruminal microflora. The EN also constitutes a sizable portion…”
Get full text
Journal Article -
11
Dietary cation-anion difference effects on performance and acid-base status of dairy cows postpartum
Published in Journal of dairy science (01-07-2007)“…Our objective was to examine the effect of dietary cation-anion difference (DCAD) on performance and acid-base status of cows postpartum. Sixteen Holstein and…”
Get more information
Journal Article -
12
Structure−Function Relationships for Inhibitors of β-Amyloid Toxicity Containing the Recognition Sequence KLVFF
Published in Biochemistry (Easton) (03-07-2001)“…β-Amyloid (Aβ), the primary protein component of Alzheimer's plaques, is neurotoxic when aggregated into fibrils. We have devised a modular strategy for…”
Get full text
Journal Article -
13
Within-day feeding behavior of lactating dairy cows measured using a real-time control system
Published in Journal of dairy science (01-05-2005)“…The suitability of a statistical model for describing within-day feeding behavior, and potential relationships between model parameters and commonly measured…”
Get more information
Journal Article -
14
Correlation of β-Amyloid Aggregate Size and Hydrophobicity with Decreased Bilayer Fluidity of Model Membranes
Published in Biochemistry (Easton) (22-08-2000)“…β-amyloid peptide (Aβ) is the primary constituent of senile plaques, a defining feature of Alzheimer's disease. Aggregated Aβ is toxic to neurons, but the…”
Get full text
Journal Article -
15
Maximizing profit on New England organic dairy farms: an economic comparison of 4 total mixed rations for organic Holsteins and Jerseys
Published in Journal of dairy science (01-06-2011)“…The objective of these experiments was to compare 4 total mixed rations fed to USDA-certified organic dairy cows in New England. Forty-eight Jersey cows from…”
Get more information
Journal Article -
16
In vitro fermentation characteristics of selected oligosaccharides by swine fecal microflora
Published in Journal of animal science (01-10-2003)“…The objective of this study was to quantify the fermentation characteristics of oligosaccharides present in feed ingredients or isolated for dietary…”
Get full text
Journal Article -
17
Contractile properties and sarcoplasmic reticulum calcium content in type I and type II skeletal muscle fibres in active aged humans
Published in The Journal of physiology (01-06-2015)“…Key points Muscle weakness in old age is due in large part to an overall loss of skeletal muscle tissue, but it remains uncertain how much also stems from…”
Get full text
Journal Article -
18
Housekeeping gene expression in bovine liver is affected by physiological state, feed intake, and dietary treatment
Published in Journal of dairy science (01-05-2007)“…Selection of appropriate housekeeping genes (HKG) for normalization of quantitative PCR data for genes of interest is critical for interpretation of results…”
Get more information
Journal Article -
19
Effects of creatine supplementation on housekeeping genes in human skeletal muscle using real-time RT-PCR
Published in Physiological genomics (15-01-2003)“…School of Health Sciences, Deakin University, Burwood, Victoria 3125, Australia The present study examined the validity and reliability of measuring the…”
Get full text
Journal Article -
20
Impact of exercise training status on the fiber type-specific abundance of proteins regulating intramuscular lipid metabolism
Published in Journal of applied physiology (1985) (01-02-2020)“…Endurance training enhances the capacity for fat oxidation during exercise due to increased utilization of intramuscular lipid (IMCL). This study…”
Get full text
Journal Article