Search Results - "MURPHY, N."
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The Atlantic Multidecadal Oscillation without a role for ocean circulation
Published in Science (American Association for the Advancement of Science) (16-10-2015)“…The Atlantic Multidecadal Oscillation (AMO) is a major mode of climate variability with important societal impacts. Most previous explanations identify the…”
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Review: Synovial Cell Metabolism and Chronic Inflammation in Rheumatoid Arthritis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-07-2018)“…Metabolomic studies of body fluids show that immune‐mediated inflammatory diseases such as rheumatoid arthritis (RA) are associated with metabolic disruption…”
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Analysis and interpretation of microplate-based oxygen consumption and pH data
Published in Methods in enzymology (2014)“…Breakthrough technologies to measure cellular oxygen consumption and proton efflux are reigniting the study of cellular energetics by increasing the scope and…”
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Secondary organic aerosol association with cardiorespiratory disease mortality in the United States
Published in Nature communications (16-12-2021)“…Fine particle pollution, PM 2.5 , is associated with increased risk of death from cardiorespiratory diseases. A multidecadal shift in the United States (U.S.)…”
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The role of historical forcings in simulating the observed Atlantic multidecadal oscillation
Published in Geophysical research letters (16-03-2017)“…We analyze the Atlantic multidecadal oscillation (AMO) in the preindustrial (PI) and historical (HIST) simulations from the Coupled Model Intercomparison…”
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Branched-chain amino acid catabolism fuels adipocyte differentiation and lipogenesis
Published in Nature chemical biology (01-01-2016)“…Stable-isotope tracing and metabolomics analysis comparing pre-adipocytes and differentiated adipocytes revealed a shift from glucose and glutamine utilization…”
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High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria
Published in PloS one (25-07-2011)“…Recently developed technologies have enabled multi-well measurement of O(2) consumption, facilitating the rate of mitochondrial research, particularly…”
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Reactive organic carbon emissions from volatile chemical products
Published in Atmospheric chemistry and physics (31-03-2021)“…Volatile chemical products (VCPs) are an increasingly important source of anthropogenic reactive organic carbon (ROC) emissions. Among these sources are…”
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Genetic variation across the human olfactory receptor repertoire alters odor perception
Published in Proceedings of the National Academy of Sciences - PNAS (07-05-2019)“…Humans use a family of more than 400 olfactory receptors (ORs) to detect odors, but there is currently no model that can predict olfactory perception from…”
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A joint NCBI and EMBL-EBI transcript set for clinical genomics and research
Published in Nature (London) (14-04-2022)“…Comprehensive genome annotation is essential to understand the impact of clinically relevant variants. However, the absence of a standard for clinical…”
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Vitamin D, Covid-19 and Children
Published in Irish medical journal (03-04-2020)Get full text
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An epidemiological study of pulmonary arterial hypertension
Published in The European respiratory journal (01-07-2007)“…All hospitalisations for pulmonary arterial hypertension (PAH) in the Scottish population were examined to determine the epidemiological features of PAH. These…”
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Critical Role of Glucose Metabolism in Rheumatoid Arthritis Fibroblast‐like Synoviocytes
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-07-2016)“…Objective Up‐regulation of glucose metabolism has been implicated not only in tumor cell growth but also in immune cells upon activation. However, little is…”
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Historical forcings as main drivers of the Atlantic multidecadal variability in the CESM large ensemble
Published in Climate dynamics (01-05-2018)“…Previous studies suggest that internal variability, in particular the Atlantic Meridional Overturning Circulation (AMOC), drives the Atlantic Multidecadal…”
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15
Development of phenotype algorithms using electronic medical records and incorporating natural language processing
Published in BMJ (Online) (24-04-2015)“…Electronic medical records are emerging as a major source of data for clinical and translational research studies, although phenotypes of interest need to be…”
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Regulation of Substrate Utilization by the Mitochondrial Pyruvate Carrier
Published in Molecular cell (06-11-2014)“…Pyruvate lies at a central biochemical node connecting carbohydrate, amino acid, and fatty acid metabolism, and the regulation of pyruvate flux into…”
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Polyphenol supplementation and executive functioning in overweight and obese adults at risk of cognitive impairment: A systematic review and meta-analysis
Published in PloS one (25-05-2023)“…Increasing evidence indicates a link between obesity and cognitive impairment. Furthermore, there is limited literature regarding the effect of polyphenols, a…”
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Towards task-based assessment of CT performance: System and object MTF across different reconstruction algorithms
Published in Medical physics (Lancaster) (01-07-2012)“…Purpose: To investigate a measurement method for evaluating the resolution properties of CT imaging systems across reconstruction algorithms, dose, and…”
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Simulation of organic aerosol formation during the CalNex study: updated mobile emissions and secondary organic aerosol parameterization for intermediate-volatility organic compounds
Published in Atmospheric chemistry and physics (14-04-2020)“…We describe simulations using an updated version of the Community Multiscale Air Quality model version 5.3 (CMAQ v5.3) to investigate the contribution of…”
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The Community Multiscale Air Quality (CMAQ) model versions 5.3 and 5.3.1: system updates and evaluation
Published in Geoscientific Model Development (20-05-2021)“…The Community Multiscale Air Quality (CMAQ) model version 5.3 (CMAQ53), released to the public in August 2019 and followed by version 5.3.1 (CMAQ531) in…”
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