Search Results - "MURPHY, G."

HPA axis in major depression: cortisol, clinical symptomatology and genetic variation predict cognition by Keller, J, Gomez, R, Williams, G, Lembke, A, Lazzeroni, L, Murphy, G M, Schatzberg, A F

“…The hypothalamic–pituitary–adrenal (HPA) axis has been implicated in the pathophysiology of a variety of mood and cognitive disorders. Neuroendocrine studies…”
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Neuroimaging in autism spectrum disorder: brain structure and function across the lifespan by Ecker, Christine, Dr, Bookheimer, Susan Y, Prof, Murphy, Declan G M, Prof

“…Summary Over the past decade, in-vivo MRI studies have provided many invaluable insights into the neural substrates underlying autism spectrum disorder (ASD),…”
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Gallium-68 Prostate-specific Membrane Antigen Positron Emission Tomography in Advanced Prostate Cancer—Updated Diagnostic Utility, Sensitivity, Specificity, and Distribution of Prostate-specific Membrane Antigen-avid Lesions: A Systematic Review and Meta-analysis by Perera, Marlon, Papa, Nathan, Roberts, Matthew, Williams, Michael, Udovicich, Cristian, Vela, Ian, Christidis, Daniel, Bolton, Damien, Hofman, Michael S., Lawrentschuk, Nathan, Murphy, Declan G.

“…Accurate staging of high-risk localised, advanced, and metastatic prostate cancer is becoming increasingly more important in guiding local and systemic…”
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Short-chain fatty acids as potential regulators of skeletal muscle metabolism and function by Frampton, James, Murphy, Kevin G., Frost, Gary, Chambers, Edward S.

“…A key metabolic activity of the gut microbiota is the fermentation of non-digestible carbohydrate, which generates short-chain fatty acids (SCFAs) as the…”
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The sensitivity of PM2.5 acidity to meteorological parameters and chemical composition changes: 10-year records from six Canadian monitoring sites by Ye Tao, Murphy, Jennifer G

“…Aerosol pH is difficult to measure directly but can be calculated if the chemical composition is known with sufficient accuracy and precision to calculate the…”
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Routine use of viscoelastic blood tests for diagnosis and treatment of coagulopathic bleeding in cardiac surgery: updated systematic review and meta-analysis by Serraino, G.F., Murphy, G.J.

“…Viscoelastic point-of-care tests are commonly used to provide prompt diagnosis of coagulopathy and allow targeted treatments in bleeding patients. We updated…”
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Structure and function of matrix metalloproteinases and TIMPs by NAGASE, Hideaki, VISSE, Robert, MURPHY, Gillian

“…Matrix metalloproteinases (MMPs), also called matrixins, function in the extracellular environment of cells and degrade both matrix and non-matrix proteins…”
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Pemigatinib for previously treated, locally advanced or metastatic cholangiocarcinoma: a multicentre, open-label, phase 2 study by Abou-Alfa, Ghassan K, Sahai, Vaibhav, Hollebecque, Antoine, Vaccaro, Gina, Melisi, Davide, Al-Rajabi, Raed, Paulson, Andrew S, Borad, Mitesh J, Gallinson, David, Murphy, Adrian G, Oh, Do-Youn, Dotan, Efrat, Catenacci, Daniel V, Van Cutsem, Eric, Ji, Tao, Lihou, Christine F, Zhen, Huiling, Féliz, Luis, Vogel, Arndt

“…Fibroblast growth factor receptor (FGFR) 2 gene alterations are involved in the pathogenesis of cholangiocarcinoma. Pemigatinib is a selective, potent, oral…”
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The Role of CDK4/6 Inhibition in Breast Cancer by Murphy, Conleth G., Dickler, Maura N.

“…Imbalance of the cyclin D and cyclin‐dependent kinase (CDK) pathway in cancer cells may result in diversion away from a pathway to senescence and toward a more…”
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Endocrine resistance in hormone-responsive breast cancer: mechanisms and therapeutic strategies by Murphy, Conleth G, Dickler, Maura N

“…The majority of breast cancers may be considered hormone responsive due to expression of hormone receptors (HR+). Although endocrine therapy is always…”
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Small molecule immunomodulation: the tumor microenvironment and overcoming immune escape by Osipov, Arsen, Saung, May Tun, Zheng, Lei, Murphy, Adrian G

“…Immunotherapy has led to a paradigm shift in the treatment of many advanced malignancies. Despite the success in treatment of tumors like non-small cell lung…”
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Stereotactic Abative Body Radiotherapy (SABR) for Oligometastatic Prostate Cancer: A Prospective Clinical Trial by Siva, Shankar, Bressel, Mathias, Murphy, Declan G., Shaw, Mark, Chander, Sarat, Violet, John, Tai, Keen Hun, Udovicich, Cristian, Lim, Andrew, Selbie, Lisa, Hofman, Michael S., Kron, Tomas, Moon, Daniel, Goad, Jeremy, Lawrentschuk, Nathan, Foroudi, Farshad

“…Stereotactic ablative body radiotherapy (SABR) is an emerging treatment option for oligometastatic prostate cancer. However, limited prospective evidence is…”
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Effect of gender on clinical presentation in systemic lupus erythematosus by Murphy, Grainne, Isenberg, David

“…The incidence of SLE is markedly increased in females of child-bearing age. Although males are protected in terms of incidence of disease, it is unclear…”
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Efficacy and Safety of Mirvetuximab Soravtansine in Patients With Platinum-Resistant Ovarian Cancer With High Folate Receptor Alpha Expression: Results From the SORAYA Study by Matulonis, Ursula A, Lorusso, Domenica, Oaknin, Ana, Pignata, Sandro, Dean, Andrew, Denys, Hannelore, Colombo, Nicoletta, Van Gorp, Toon, Konner, Jason A, Marin, Margarita Romeo, Harter, Philipp, Murphy, Conleth G, Wang, Jiuzhou, Noble, Elizabeth, Esteves, Brooke, Method, Michael, Coleman, Robert L

“…Single-agent chemotherapies have limited activity and considerable toxicity in patients with platinum-resistant epithelial ovarian cancer (PROC). Mirvetuximab…”
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Trait mindfulness & self-reported driving behaviour by Murphy, G., Matvienko-Sikar, K.

“…Trait mindfulness is considered a protective factor for a number of risky health behaviours, yet the relationship between mindfulness and driving behaviours…”
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Systematic Review and Cumulative Analysis of Perioperative Outcomes and Complications After Robot-assisted Radical Cystectomy by Novara, Giacomo, Catto, James W.F, Wilson, Timothy, Annerstedt, Magnus, Chan, Kevin, Murphy, Declan G, Motttrie, Alexander, Peabody, James O, Skinner, Eila C, Wiklund, Peter N, Guru, Khurshid A, Yuh, Bertram

“…Abstract Context Although open radical cystectomy (ORC) is still the standard approach, laparoscopic radical cystectomy (LRC) and robot-assisted radical…”
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Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults by Chambers, Edward S, Viardot, Alexander, Psichas, Arianna, Morrison, Douglas J, Murphy, Kevin G, Zac-Varghese, Sagen E K, MacDougall, Kenneth, Preston, Tom, Tedford, Catriona, Finlayson, Graham S, Blundell, John E, Bell, Jimmy D, Thomas, E Louise, Mt-Isa, Shahrul, Ashby, Deborah, Gibson, Glen R, Kolida, Sofia, Dhillo, Waljit S, Bloom, Stephen R, Morley, Wayne, Clegg, Stuart, Frost, Gary

“…The colonic microbiota ferment dietary fibres, producing short chain fatty acids. Recent evidence suggests that the short chain fatty acid propionate may play…”
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The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents by Psichas, A, Sleeth, M L, Murphy, K G, Brooks, L, Bewick, G A, Hanyaloglu, A C, Ghatei, M A, Bloom, S R, Frost, G

“…Background and Objectives: The gut hormones peptide YY (PYY) and glucagon-like peptide 1 (GLP-1) acutely suppress appetite. The short chain fatty acid (SCFA)…”
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Anatomical predictors of aphasia recovery: a tractography study of bilateral perisylvian language networks by FORKEL, Stephanie J, DE SCHOTTEN, Michel Thiebaut, DELL'ACQUA, Flavio, KALRA, Lalit, MURPHY, Declan G. M, WILLIAMS, Steven C. R, CATANI, Marco

“…Stroke-induced aphasia is associated with adverse effects on quality of life and the ability to return to work. For patients and clinicians the possibility of…”
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Episodic Future Thinking as a Brief Alcohol Intervention for Heavy Drinking College Students: A Pilot Feasibility Study by Voss, Andrew T., Jorgensen, Margaret K., Murphy, James G.

“…Episodic future thinking (EFT), an exercise that involves cognitive simulation of future events, has demonstrated proximal effects on alcohol demand and…”
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