Search Results - "MURPHY, Declan G. M"
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Neuroimaging in autism spectrum disorder: brain structure and function across the lifespan
Published in Lancet neurology (01-11-2015)“…Summary Over the past decade, in-vivo MRI studies have provided many invaluable insights into the neural substrates underlying autism spectrum disorder (ASD),…”
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Anatomical predictors of aphasia recovery: a tractography study of bilateral perisylvian language networks
Published in Brain (London, England : 1878) (01-07-2014)“…Stroke-induced aphasia is associated with adverse effects on quality of life and the ability to return to work. For patients and clinicians the possibility of…”
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Modeling flexible behavior in childhood to adulthood shows age-dependent learning mechanisms and less optimal learning in autism in each age group
Published in PLoS biology (27-10-2020)“…Flexible behavior is critical for everyday decision-making and has been implicated in restricted, repetitive behaviors (RRB) in autism spectrum disorder (ASD)…”
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Describing the brain in autism in five dimensions--magnetic resonance imaging-assisted diagnosis of autism spectrum disorder using a multiparameter classification approach
Published in The Journal of neuroscience (11-08-2010)“…Autism spectrum disorder (ASD) is a neurodevelopmental condition with multiple causes, comorbid conditions, and a wide range in the type and severity of…”
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Frontal and occipital brain glutathione levels are unchanged in autistic adults
Published in PloS one (15-08-2024)“…The neurobiological underpinnings of Autism Spectrum Disorder (ASD) are diverse and likely multifactorial. One possible mechanism is increased oxidative stress…”
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The 'PSILAUT' protocol: an experimental medicine study of autistic differences in the function of brain serotonin targets of psilocybin
Published in BMC psychiatry (25-04-2024)“…The underlying neurobiology of the complex autism phenotype remains obscure, although accumulating evidence implicates the serotonin system and especially the…”
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Towards robust and replicable sex differences in the intrinsic brain function of autism
Published in Molecular autism (01-03-2021)“…Marked sex differences in autism prevalence accentuate the need to understand the role of biological sex-related factors in autism. Efforts to unravel sex…”
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Sex differences in social brain neural responses in autism: temporal profiles of configural face-processing within data-driven time windows
Published in Scientific reports (18-06-2024)“…Face-processing timing differences may underlie visual social attention differences between autistic and non-autistic people, and males and females. This study…”
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Comparison of ICD-10R, DSM-IV-TR and DSM-5 in an Adult Autism Spectrum Disorder Diagnostic Clinic
Published in Journal of autism and developmental disorders (01-11-2013)“…An Autism Spectrum Disorder (ASD) diagnosis is often used to access services. We investigated whether ASD diagnostic outcome varied when DSM-5 was used…”
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Cortical Anatomy in Autism Spectrum Disorder: An In Vivo MRI Study on the Effect of Age
Published in Cerebral cortex (New York, N.Y. 1991) (01-06-2010)“…There is increasing evidence that children with autism spectrum disorder (ASD) have age-related differences from controls in cortical volume (CV). It is less…”
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Response inhibition and serotonin in autism: a functional MRI study using acute tryptophan depletion
Published in Brain (London, England : 1878) (01-09-2014)“…It has been suggested that the restricted, stereotyped and repetitive behaviours typically found in autism are underpinned by deficits of inhibitory control…”
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Is postnatal depression a distinct subtype of major depressive disorder? An exploratory study
Published in Archives of women's mental health (01-04-2021)“…Postnatal depression (PND) has an estimated prevalence of 6.5 to 12.9%. In addition to the direct consequences for women, PND also interferes with the…”
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Rapid white matter changes in children with conduct problems during a parenting intervention
Published in Translational psychiatry (04-11-2023)“…Studies report that the microstructural integrity of the uncinate fasciculus (UF; connecting the anterior temporal lobe to the orbitofrontal cortex) is…”
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Gray matter covariations and core symptoms of autism: the EU-AIMS Longitudinal European Autism Project
Published in Molecular autism (30-10-2020)“…Voxel-based morphometry (VBM) studies in autism spectrum disorder (autism) have yielded diverging results. This might partly be attributed to structural…”
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Exploratory evidence for differences in GABAergic regulation of auditory processing in autism spectrum disorder
Published in Translational psychiatry (18-10-2023)“…Altered reactivity and responses to auditory input are core to the diagnosis of autism spectrum disorder (ASD). Preclinical models implicate ϒ-aminobutyric…”
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A Whole-Brain Investigation of White Matter Microstructure in Adolescents with Conduct Disorder
Published in PloS one (06-06-2016)“…The biological basis of severe antisocial behaviour in adolescents is poorly understood. We recently reported that adolescents with conduct disorder (CD) have…”
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Psychopharmacological prescriptions for people with autism spectrum disorder (ASD): a multinational study
Published in Psychopharmacology (01-03-2014)“…Rationale Previous studies on psychotropic drugs prescribing in autism spectrum disorder (ASD) were from the USA or the UK. However, these studies may not be…”
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Obsessions and compulsions in Asperger syndrome and high-functioning autism
Published in British journal of psychiatry (01-06-2005)“…Obsessive-compulsive behaviours are common and disabling in autistic-spectrum disorders (ASD) but little is known about how they compare with those experienced…”
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Modulation of striatal functional connectivity differences in adults with and without autism spectrum disorder in a single-dose randomized trial of cannabidivarin
Published in Molecular autism (01-07-2021)“…Autism spectrum disorder (ASD) has a high cost to affected individuals and society, but treatments for core symptoms are lacking. To expand intervention…”
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Fine-grained topographic organization within somatosensory cortex during resting-state and emotional face-matching task and its association with ASD traits
Published in Translational psychiatry (27-07-2023)“…Sensory atypicalities are particularly common in autism spectrum disorders (ASD). Nevertheless, our knowledge about the divergent functioning of the underlying…”
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