Search Results - "MUROTA, S"

IL-6 increases endothelial permeability in vitro by Maruo, N, Morita, I, Shirao, M, Murota, S

“…The effect of interleukin 6 (IL-6) on endothelial permeability was examined by measuring fluorescein isothiocyanate-labeled albumin flux across an endothelial…”
Get more information

Oxidative neuronal death caused by glutamate uptake inhibition in cultured hippocampal neurons by Himi, Toshiyuki, Ikeda, Masayuki, Yasuhara, Tadashi, Murota, Sei-itsu

“…Glutamate transporters are coupled with cystine/glutamate antiporters to supply cystine as a component of glutathione, an important antioxidant. We sought…”
Get full text

Novel mechanism for age-related macular degeneration: An equilibrium shift between the angiogenesis factors VEGF and PEDF by Ohno-Matsui, Kyoko, Morita, Ikuo, Tombran-Tink, Joyce, Mrazek, David, Onodera, Mitsue, Uetama, Tomoko, Hayano, Masato, Murota, Sei-itsu, Mochizuki, Manabu

“…We investigated gene expression profiles of vascular endothelial growth factor (VEGF) and pigment epithelium‐derived factor (PEDF) in differentiated and…”
Get full text

The inhibitory effect of vitamin K2 (menatetrenone) on bone resorption may be related to its side chain by HARA, K, AKIYAMA, Y, NAKAMURA, T, MUROTA, S, MORITA, I

“…Although the effects of vitamin K2 and vitamin K1 on bone metabolism have been reported, the difference between them has not been investigated. We now show the…”
Get full text

The inhibitory effect of vitamin K 2 (Menatetrenone) on bone resorption may be related to its side chain by Hara, K., Akiyama, Y., Nakamura, T., Murota, S., Morita, I.

“…Although the effects of vitamin K 2 and vitamin K 1 on bone metabolism have been reported, the difference between them has not been investigated. We now show…”
Get full text

Expression and role of mannose receptor/terminal high-mannose type oligosaccharide on osteoclast precursors during osteoclast formation by Morishima, S, Morita, I, Tokushima, T, Kawashima, H, Miyasaka, M, Omura, K, Murota, S

“…Osteoclasts are formed from hematopoietic precursors via cell-cell fusion. We have previously reported that mannose residues are expressed on the outer…”
Get full text

Relationship between the ability to support differentiation of osteoclast-like cells and adipogenesis in murine stromal cells derived from bone marrow by Sakaguchi, K., Morita, I., Murota, S.

“…In vitro osteoclast differentiation is supported by stromal cells. In order to isolate a stromal cell line that can support osteoclast differentiation, 22 cell…”
Get full text

Inhibition of phosphatidylinositol-3 kinase/Akt or mitogen-activated protein kinase signaling sensitizes endothelial cells to TNF-alpha cytotoxicity by Zhang, L, Himi, T, Morita, I, Murota, S

“…Bovine carotid artery endothelial (BAE) cells are resistant to tumor necrosis factor-alpha (TNF), like most other cells. We examined if mitogen-activated…”
Get full text

Expression of IL-6 Receptor and GP130 in Mouse Bone Marrow Cells During Osteoclast Differentiation by Gao, Y, Morita, I, Maruo, N, Kubota, T, Murota, S, Aso, T

“…Interleukin-6 (IL-6) has been postulated as a possible mediator of bone loss after estrogen deficiency, and its signal is transduced via glycoprotein 130…”
Get full text

Effect of carbon dioxide and oxygen on endothelin production by cultured porcine cerebral endothelial cells by YOSHIMOTO, S, ISHIZAKI, Y, SASAKI, T, MUROTA, S.-I

“…We have previously reported the production of endothelin, a potent vasoconstrictor peptide, by porcine cerebral microvessel endothelia and suggested its…”
Get full text

Involvement of cholesterol in osteoclast-like cell formation via cellular fusion by Sato, T., Morita, I., Murota, S.

“…Osteoclasts, the bone resorbing cells, are formed from hematopoietic precursors via plasma membrane fusion. To investigate the possibility that cholesterol is…”
Get full text

Reduction of nitric oxide producing activity associated with in vitro aging in cultured human umbilical vein endothelial cell by Sato, I, Morita, I, Kaji, K, Ikeda, M, Nagao, M, Murota, S

“…To investigate the involvement of nitric oxide (NO) in the pathogenesis of the cardiovascular system with aging, we studied the basal release of NO in cultured…”
Get more information

Human uterine myometrial smooth muscle cell proliferation and vascular endothelial growth-factor production in response to platelet-derived growth factor by Taniguchi, Y, Morita, I, Kubota, T, Murota, S, Aso, T

“…It has been recognized that tissue-specific growth factors and angiogenic factors play important roles in the growth of tumors and in the tissue-repair system…”
Get full text

Eicosapentaenoic acid inhibits bone loss due to ovariectomy in rats by Sakaguchi, K, Morita, I, Murota, S

“…Eicosapentaenoic acid (EPA), one of the polyunsaturated fatty acids, is well-known to have a wide variety of beneficial biological functions. In the present…”
Get more information

Human oral squamous cell carcinoma cell lines promote angiogenesis via expression of vascular endothelial growth factor and upregulation of KDR/flk-1 expression in endothelial cells by Michi, Y., Morita, I., Amagasa, T., Murota, S.

“…Angiogenesis is an important phenomenon for the growth and metastasis of solid tumors. The present study examined the characterization of angiogenic factors…”
Get full text

Inhibitory effects of eicosapentaenoic acid (EPA) on the hypoxia/reoxygenation-induced tyrosine kinase activation in cultured human umbilical vein endothelial cells by Zhang, Y.W., Yao, X.S., Murota, S., Morita, I.

“…We have previously reported that the n-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) inhibited the abnormal gap junctional intercellular…”
Get full text

Screening of anti-hypoxia/reoxygenation agents by an in vitro model. Part 1: Natural inhibitors for protein tyrosine kinase activated by hypoxia/reoxygenation in cultured human umbilical vein endothelial cells by Zhang, Y W, Morita, I, Shao, G, Yao, X S, Murota, S

“…Protein tyrosine kinase (PTK) signaling pathways play important roles in ischemia/reperfusion (I/R) or hypoxia/reoxygenation (H/R) injuries. Inhibition of PTK…”
Get more information

Simvastatin inhibits the division and induces neurite-like outgrowth in PC12 cells by SATO-SUZUKI, I, MUROTA, S.-I

“…Simvastatin, a potent 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. inhibited cell division in a dose dependent fashion and induced…”
Get full text

Differential effects of nitric oxide on the activity of prostaglandin endoperoxide H synthase-1 and -2 in vascular endothelial cells by Onodera, M., Morita, I., Mano, Y., Murota, S.

“…A number of studies have demonstrated that prostacyclin and nitric oxide (NO) regulate blood pressure, blood flow and platelet aggregation. In this paper, we…”
Get full text

Involvement of adhesion molecules LFA-1 and ICAM-1 in osteoclast development by Kurachi, T, Morita, I, Murota, S

“…We report here that leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1) are involved in osteoclast development…”
Get more information