Search Results - "MURATA, Shiro"

A canine chimeric monoclonal antibody targeting PD-L1 and its clinical efficacy in canine oral malignant melanoma or undifferentiated sarcoma by Maekawa, Naoya, Konnai, Satoru, Takagi, Satoshi, Kagawa, Yumiko, Okagawa, Tomohiro, Nishimori, Asami, Ikebuchi, Ryoyo, Izumi, Yusuke, Deguchi, Tatsuya, Nakajima, Chie, Kato, Yukinari, Yamamoto, Keiichi, Uemura, Hidetoshi, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko

“…Immunotherapy targeting immune checkpoint molecules, programmed cell death 1 (PD-1) and PD-ligand 1 (PD-L1), using therapeutic antibodies has been widely used…”
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Immune exhaustion during chronic infections in cattle by KONNAI, Satoru, MURATA, Shiro, OHASHI, Kazuhiko

“…Recently, dysfunction of antigen-specific T cells is well documented as T-cell exhaustion and has been defined by the loss of effector functions during chronic…”
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Immunohistochemical Analysis of PD-L1 Expression in Canine Malignant Cancers and PD-1 Expression on Lymphocytes in Canine Oral Melanoma by Maekawa, Naoya, Konnai, Satoru, Okagawa, Tomohiro, Nishimori, Asami, Ikebuchi, Ryoyo, Izumi, Yusuke, Takagi, Satoshi, Kagawa, Yumiko, Nakajima, Chie, Suzuki, Yasuhiko, Kato, Yukinari, Murata, Shiro, Ohashi, Kazuhiko

“…Spontaneous cancers are common diseases in dogs. Among these, some malignant cancers such as oral melanoma, osteosarcoma, hemangiosarcoma, and mast cell tumor…”
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Characterization of SpsQ from Staphylococcus pseudintermedius as an affinity chromatography ligand for canine therapeutic antibodies by Takeuchi, Hiroto, Nakajima, Chie, Konnai, Satoru, Maekawa, Naoya, Okagawa, Tomohiro, Usui, Masaru, Tamura, Yutaka, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko

“…Coagulase-positive Staphylococci express protein A, which binds to host antibodies, to evade the immune system. Taking advantage of its specific binding to…”
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PD-L1 immunohistochemistry for canine cancers and clinical benefit of anti-PD-L1 antibody in dogs with pulmonary metastatic oral malignant melanoma by Maekawa, Naoya, Konnai, Satoru, Nishimura, Maki, Kagawa, Yumiko, Takagi, Satoshi, Hosoya, Kenji, Ohta, Hiroshi, Kim, Sangho, Okagawa, Tomohiro, Izumi, Yusuke, Deguchi, Tatsuya, Kato, Yukinari, Yamamoto, Satoshi, Yamamoto, Keiichi, Toda, Mikihiro, Nakajima, Chie, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko

“…Immunotherapy targeting programmed cell death 1 (PD-1) and PD-ligand 1 (PD-L1) represents promising treatments for human cancers. Our previous studies…”
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Research Note: Characterization of S-Meq containing the deletion in Meq protein's transactivation domain in a Marek's disease virus strain in Japan by Murata, Shiro, Yamamoto, Eiji, Sakashita, Natsumi, Maekawa, Naoya, Okagawa, Tomohiro, Konnai, Satoru, Ohashi, Kazuhiko

“…Marek's disease virus (MDV) causes malignant lymphomas in chickens (Marek's disease; MD). Although MD has caused significant economic losses to the poultry…”
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Expression of PD-L1 on canine tumor cells and enhancement of IFN-γ production from tumor-infiltrating cells by PD-L1 blockade by Maekawa, Naoya, Konnai, Satoru, Ikebuchi, Ryoyo, Okagawa, Tomohiro, Adachi, Mami, Takagi, Satoshi, Kagawa, Yumiko, Nakajima, Chie, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko

“…Programmed death 1 (PD-1), an immunoinhibitory receptor, and programmed death ligand 1 (PD-L1), its ligand, together induce the "exhausted" status in…”
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Combined Immune Checkpoint Blockade Enhances Antiviral Immunity against Bovine Leukemia Virus by Nakamura, Hayato, Konnai, Satoru, Okagawa, Tomohiro, Maekawa, Naoya, Sajiki, Yamato, Watari, Kei, Kamitani, Kana, Saito, Maya, Kato, Yukinari, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko

“…Bovine leukemia virus (BLV) is a retrovirus that causes enzootic bovine leukosis (EBL) in cattle and is widespread in many countries, including Japan. Recent…”
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Safety and clinical efficacy of an anti-PD-L1 antibody (c4G12) in dogs with advanced malignant tumours by Maekawa, Naoya, Konnai, Satoru, Hosoya, Kenji, Kim, Sangho, Kinoshita, Ryohei, Deguchi, Tatsuya, Owaki, Ryo, Tachibana, Yurika, Yokokawa, Madoka, Takeuchi, Hiroto, Kagawa, Yumiko, Takagi, Satoshi, Ohta, Hiroshi, Kato, Yukinari, Yamamoto, Satoshi, Yamamoto, Keiichi, Suzuki, Yasuhiko, Okagawa, Tomohiro, Murata, Shiro, Ohashi, Kazuhiko

“…Immune checkpoint inhibitors (ICIs) have been developed for canine tumour treatment, and pilot clinical studies have demonstrated their antitumour efficacy in…”
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Distinct polymorphisms in a single herpesvirus gene are capable of enhancing virulence and mediating vaccinal resistance by Conradie, Andelé M, Bertzbach, Luca D, Trimpert, Jakob, Patria, Joseph N, Murata, Shiro, Parcells, Mark S, Kaufer, Benedikt B

“…Modified-live herpesvirus vaccines are widely used in humans and animals, but field strains can emerge that have a higher virulence and break vaccinal…”
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Exploration of serum biomarkers in dogs with malignant melanoma receiving anti-PD-L1 therapy and potential of COX-2 inhibition for combination therapy by Maekawa, Naoya, Konnai, Satoru, Asano, Yumie, Sajiki, Yamato, Deguchi, Tatsuya, Okagawa, Tomohiro, Watari, Kei, Takeuchi, Hiroto, Takagi, Satoshi, Hosoya, Kenji, Kim, Sangho, Ohta, Hiroshi, Kato, Yukinari, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko

“…Immune checkpoint inhibitors (ICIs) such as anti-PD-L1 antibodies are widely used to treat human cancers, and growing evidence suggests that ICIs are promising…”
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Genetic characterization of a Marek's disease virus strain isolated in Japan by Murata, Shiro, Machida, Yuka, Isezaki, Masayoshi, Maekawa, Naoya, Okagawa, Tomohiro, Konnai, Satoru, Ohashi, Kazuhiko

“…Marek's disease virus (MDV) causes malignant lymphomas in chickens (Marek's disease, MD). MD is currently controlled by vaccination; however, MDV strains have…”
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PD-L1 expression in equine malignant melanoma and functional effects of PD-L1 blockade by Ganbaatar, Otgontuya, Konnai, Satoru, Okagawa, Tomohiro, Nojima, Yutaro, Maekawa, Naoya, Minato, Erina, Kobayashi, Atsushi, Ando, Ryo, Sasaki, Nobuya, Miyakoshi, Daisuke, Ichii, Osamu, Kato, Yukinari, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko

“…Programmed death-1 (PD-1) is an immunoinhibitory receptor expressed on lymphocytes. Interaction of PD-1 with its ligand PD-ligand 1 (PD-L1) delivers inhibitory…”
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Enhancement of interleukin-2 production by bovine peripheral blood mononuclear cells treated with the combination of anti-programmed death-ligand 1 and cytotoxic T lymphocyte antigen 4 chimeric monoclonal antibodies by WATARI, Kei, KONNAI, Satoru, OKAGAWA, Tomohiro, MAEKAWA, Naoya, SAJIKI, Yamato, KATO, Yukinari, SUZUKI, Yasuhiko, MURATA, Shiro, OHASHI, Kazuhiko

“…Our previous studies demonstrate the therapeutic efficacy against bovine diseases of an anti-bovine programmed death-ligand 1 (PD-L1) chimeric antibody. In…”
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Selection of reference genes for quantitative PCR analysis in poultry red mite (Dermanyssus gallinae) by ARIIZUMI, Takuma, MURATA, Shiro, FUJISAWA, Sotaro, ISEZAKI, Masayoshi, MAEKAWA, Naoya, OKAGAWA, Tomohiro, SATO, Takumi, OISHI, Eiji, TANENO, Akira, KONNAI, Satoru, OHASHI, Kazuhiko

“…Poultry red mites (PRMs, Dermanyssus gallinae) are harmful ectoparasites that affect farmed chickens and cause serious economic losses in the poultry industry…”
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Molecular characterization of feline immune checkpoint molecules and establishment of PD-L1 immunohistochemistry for feline tumors by Maekawa, Naoya, Konnai, Satoru, Asano, Yumie, Otsuka, Takumi, Aoki, Eri, Takeuchi, Hiroto, Kato, Yukinari, Kaneko, Mika K, Yamada, Shinji, Kagawa, Yumiko, Nishimura, Maki, Takagi, Satoshi, Deguchi, Tatsuya, Ohta, Hiroshi, Nakagawa, Takayuki, Suzuki, Yasuhiko, Okagawa, Tomohiro, Murata, Shiro, Ohashi, Kazuhiko

“…Spontaneous tumors are a major cause of death in cats. Treatment of human tumors has progressed dramatically in the past decade, partly due to the success of…”
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Analysis of gene expression in poultry red mite, Dermanyssus gallinae, by RNAscope in situ hybridization by SEO, Hikari, MURATA, Shiro, ICHII, Osamu, NAMBA, Takashi, WIN, Shwe Yee, SATO, Takumi, OISHI, Eiji, TANENO, Akira, MAEKAWA, Naoya, OKAGAWA, Tomohiro, KONNAI, Satoru, OHASHI, Kazuhiko

“…The poultry red mite (PRM; Dermanyssus gallinae) is a hematophagous ectoparasite that mainly infests chickens, and its infestation causes significant economic…”
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Tick saliva-induced programmed death-1 and PD-ligand 1 and its related host immunosuppression by Sajiki, Yamato, Konnai, Satoru, Ikenaka, Yoshinori, Gulay, Kevin Christian Montecillo, Kobayashi, Atsushi, Parizi, Luís Fernando, João, Benvindo Capela, Watari, Kei, Fujisawa, Sotaro, Okagawa, Tomohiro, Maekawa, Naoya, Logullo, Carlos, da Silva Vaz, Itabajara, Murata, Shiro, Ohashi, Kazuhiko

“…The tick Rhipicephalus microplus is a harmful parasite of cattle that causes considerable economic losses to the cattle breeding industry. Although R …”
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A TLR7 agonist activates bovine Th1 response and exerts antiviral activity against bovine leukemia virus by Sajiki, Yamato, Konnai, Satoru, Okagawa, Tomohiro, Maekawa, Naoya, Nakamura, Hayato, Kato, Yukinari, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko

“…Bovine leukemia virus (BLV) infection is a bovine chronic infection caused by BLV, a member of the genus Deltaretrovirus. In this study, we examined the…”
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The enhancement of Th1 immune response by anti-PD-L1 antibody in cattle infected with Mycobacterium avium subsp. paratuberculosis by SAJIKI, Yamato, KONNAI, Satoru, NAGATA, Reiko, KAWAJI, Satoko, NAKAMURA, Hayato, FUJISAWA, Sotaro, OKAGAWA, Tomohiro, MAEKAWA, Naoya, KATO, Yukinari, SUZUKI, Yasuhiko, MURATA, Shiro, MORI, Yasuyuki, OHASHI, Kazuhiko

“…Johne’s disease, caused by Mycobacterium avium subsp. paratuberculosis (MAP), is a chronic enteritis of ruminants. Previous studies have shown that programmed…”
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