Search Results - "MURAKOSHI, Maki"
-
1
Sodium-Glucose Cotransporter-2 Inhibitors-Miracle Drugs for the Treatment of Chronic Kidney Disease Irrespective of the Diabetes Status: Lessons from the Dedicated Kidney Disease-Focused CREDENCE and DAPA-CKD Trials
Published in International journal of molecular sciences (09-11-2022)“…Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease (CKD) and end-stage kidney disease worldwide. In Japan, the proportion of new…”
Get full text
Journal Article -
2
Circulating Tumor Necrosis Factor Receptors: A Potential Biomarker for the Progression of Diabetic Kidney Disease
Published in International journal of molecular sciences (13-03-2020)“…Despite considerable advancements in medicine, the optimal treatment for chronic kidney disease (CKD), especially diabetic kidney disease (DKD), remains a…”
Get full text
Journal Article -
3
Circulating tumor necrosis factor receptors are associated with mortality and disease severity in COVID-19 patients
Published in PloS one (11-10-2022)“…Background Although hyperinflammatory response influences the severity of coronavirus disease 2019 (COVID-19), little has been reported about the utility of…”
Get full text
Journal Article -
4
Differential organ-specific inflammatory response to progranulin in high-fat diet-fed mice
Published in Scientific reports (13-01-2021)“…Progranulin (PGRN) has been reported to bind tumor necrosis factor (TNF) receptor and to inhibit TNFα signaling. We evaluated the effect of augmentation of…”
Get full text
Journal Article -
5
Circulating tumor necrosis factor receptors are associated with mortality and disease severity in COVID-19 patients
Published in PloS one (11-10-2022)“…Background Although hyperinflammatory response influences the severity of coronavirus disease 2019 (COVID-19), little has been reported about the utility of…”
Get full text
Journal Article -
6
Potential of Modulating Aldosterone Signaling and Mineralocorticoid Receptor with microRNAs to Attenuate Diabetic Kidney Disease
Published in International journal of molecular sciences (01-01-2024)“…Diabetic Kidney Disease (DKD) is a significant complication of diabetes and primary cause of end-stage renal disease globally. The exact mechanisms underlying…”
Get full text
Journal Article -
7
Gut Microbiome and Microbiome-Derived Metabolites in Patients with End-Stage Kidney Disease
Published in International journal of molecular sciences (01-07-2023)“…The composition of the gut microbiome is altered in patients with chronic kidney disease (CKD). Dysbiosis leads to decreased levels of stool organic acids…”
Get full text
Journal Article -
8
Circulating TNF receptor levels are associated with estimated glomerular filtration rate even in healthy individuals with normal kidney function
Published in Scientific reports (27-03-2024)“…The association between serum tumor necrosis factor receptor (TNFRs: TNFR1, TNFR2) levels and estimated glomerular filtration rate (eGFR) observed in patients…”
Get full text
Journal Article -
9
Circulating kidney injury molecule‐1 as a biomarker of renal parameters in diabetic kidney disease
Published in Journal of diabetes investigation (01-03-2020)“…Aims/Introduction Urinary kidney injury molecule‐1 (KIM‐1) has been associated with proximal tubular damage in human and animal studies. Although it has been…”
Get full text
Journal Article -
10
Association between circulating tumor necrosis factor-related biomarkers and estimated glomerular filtration rate in type 2 diabetes
Published in Scientific reports (17-10-2018)“…Chronic inflammation plays a crucial role in the development/progression of diabetic kidney disease. The involvement of tumor necrosis factor (TNF)-related…”
Get full text
Journal Article -
11
Clinical predictive biomarkers for normoalbuminuric diabetic kidney disease
Published in Diabetes research and clinical practice (01-07-2018)“…A portion of patients with diabetes mellitus follow the progression of a non-albuminuria-based pathway; i.e., normoalbuminuric diabetic kidney disease…”
Get full text
Journal Article -
12
Progranulin deficiency attenuates tubulointerstitial injury in a mouse unilateral ureteral obstruction model
Published in Experimental Animals (01-01-2024)“…Progranulin (PGRN) may have two opposing effects—inflammation and anti-inflammation—in different diseases. Although previous studies have reported that PGRN is…”
Get full text
Journal Article -
13
Progranulin and Its Receptor Predict Kidney Function Decline in Patients With Type 2 Diabetes
Published in Frontiers in endocrinology (Lausanne) (01-04-2022)“…Progranulin (PGRN), a growth factor, is abundantly expressed in a broad range of tissues and cell types with pleiotropic functions including inflammation,…”
Get full text
Journal Article -
14
Fractional excretion of tumor necrosis factor receptor 1 and 2 in patients with type 2 diabetes and normal renal function
Published in Journal of diabetes investigation (01-03-2021)“…Aims/Introduction Increased concentrations of serum tumor necrosis factor (TNF) receptors (TNFRs; TNFR1 and TNFR2) are positively associated with the urinary…”
Get full text
Journal Article -
15
Development of an In-House EphA2 ELISA for Human Serum and Measurement of Circulating Levels of EphA2 in Hypertensive Patients with Renal Dysfunction
Published in Diagnostics (Basel) (01-12-2022)“…Identifying novel biomarkers of kidney function in patients with chronic kidney disease (CKD) has strong clinical value as current measures have limitations…”
Get full text
Journal Article -
16
Aspartic acid supplementation ameliorates symptoms of diabetic kidney disease in mice
Published in FEBS open bio (01-06-2020)“…Diabetic kidney disease (DKD) is among the most common and serious complications of both type 1 and type 2 diabetes. In this study, we used KK/Ta‐Ins2Akita…”
Get full text
Journal Article -
17
Effect of tonsillectomy with steroid pulse therapy on circulating tumor necrosis factor receptors 1 and 2 in IgA nephropathy
Published in Clinical and experimental nephrology (01-12-2017)“…Background High circulating levels of soluble tumor necrosis factor receptors (TNFRs: TNFR1, TNFR2) predict renal function decline in a variety of kidney…”
Get full text
Journal Article -
18
The sodium–glucose cotransporter 2 inhibitor tofogliflozin prevents diabetic kidney disease progression in type 2 diabetic mice
Published in FEBS open bio (01-12-2020)“…Tofogliflozin may prevent glomerular (enlarged mesangial area, foot process effacement, podocyte loss) and tubulointerstitial damage (increased expression of…”
Get full text
Journal Article -
19
Associations between circulating levels of FABP4 and TNF receptors are more evident in patients with type 2 diabetes mellitus than in patients with type 1 diabetes mellitus
Published in Endocrine Connections (01-11-2024)“…Fatty acid-binding protein 4 (FABP4) is an adipokine that plays significant roles in the development of insulin resistance and atherosclerosis. High levels of…”
Get full text
Journal Article -
20
Effect of Zinc Acetate Dihydrate (NobelzinR) Treatment on Anemia and Taste Disorders in Patients with Chronic Kidney Disease with Hypozincemia
Published in Acta medica Okayama (01-10-2018)“…Some patients with chronic kidney disease (CKD) receiving hemodialysis develop erythropoietin-resistant anemia, possibly due to zinc deficiency. The frequency…”
Get full text
Journal Article