Search Results - "MURAKOSHI, Maki"

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    Sodium-Glucose Cotransporter-2 Inhibitors-Miracle Drugs for the Treatment of Chronic Kidney Disease Irrespective of the Diabetes Status: Lessons from the Dedicated Kidney Disease-Focused CREDENCE and DAPA-CKD Trials by Gohda, Tomohito, Murakoshi, Maki

    “…Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease (CKD) and end-stage kidney disease worldwide. In Japan, the proportion of new…”
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    Journal Article
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    Circulating Tumor Necrosis Factor Receptors: A Potential Biomarker for the Progression of Diabetic Kidney Disease by Murakoshi, Maki, Gohda, Tomohito, Suzuki, Yusuke

    “…Despite considerable advancements in medicine, the optimal treatment for chronic kidney disease (CKD), especially diabetic kidney disease (DKD), remains a…”
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    Circulating tumor necrosis factor receptors are associated with mortality and disease severity in COVID-19 patients by Gohda, Tomohito, Murakoshi, Maki, Suzuki, Yusuke, Hiki, Makoto, Naito, Toshio, Takahashi, Kazuhisa, Tabe, Yoko

    Published in PloS one (11-10-2022)
    “…Background Although hyperinflammatory response influences the severity of coronavirus disease 2019 (COVID-19), little has been reported about the utility of…”
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    Differential organ-specific inflammatory response to progranulin in high-fat diet-fed mice by Murakoshi, Maki, Gohda, Tomohito, Adachi, Eri, Ichikawa, Saki, Hagiwara, Shinji, Suzuki, Yusuke

    Published in Scientific reports (13-01-2021)
    “…Progranulin (PGRN) has been reported to bind tumor necrosis factor (TNF) receptor and to inhibit TNFα signaling. We evaluated the effect of augmentation of…”
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    Circulating tumor necrosis factor receptors are associated with mortality and disease severity in COVID-19 patients by Tomohito Gohda, Maki Murakoshi, Yusuke Suzuki, Makoto Hiki, Toshio Naito, Kazuhisa Takahashi, Yoko Tabe

    Published in PloS one (11-10-2022)
    “…Background Although hyperinflammatory response influences the severity of coronavirus disease 2019 (COVID-19), little has been reported about the utility of…”
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    Journal Article
  6. 6

    Potential of Modulating Aldosterone Signaling and Mineralocorticoid Receptor with microRNAs to Attenuate Diabetic Kidney Disease by Hagiwara, Shinji, Gohda, Tomohito, Kantharidis, Phillip, Okabe, Jun, Murakoshi, Maki, Suzuki, Yusuke

    “…Diabetic Kidney Disease (DKD) is a significant complication of diabetes and primary cause of end-stage renal disease globally. The exact mechanisms underlying…”
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  7. 7

    Gut Microbiome and Microbiome-Derived Metabolites in Patients with End-Stage Kidney Disease by Koshida, Takeo, Gohda, Tomohito, Sugimoto, Takuya, Asahara, Takashi, Asao, Rin, Ohsawa, Isao, Gotoh, Hiromichi, Murakoshi, Maki, Suzuki, Yusuke, Yamashiro, Yuichiro

    “…The composition of the gut microbiome is altered in patients with chronic kidney disease (CKD). Dysbiosis leads to decreased levels of stool organic acids…”
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    Circulating TNF receptor levels are associated with estimated glomerular filtration rate even in healthy individuals with normal kidney function by Gohda, Tomohito, Murakoshi, Maki, Shibata, Terumi, Suzuki, Yusuke, Takemura, Hiroyuki, Tsuchiya, Koji, Okada, Tomoki, Wakita, Mitsuru, Horiuchi, Yuki, Tabe, Yoko, Kamei, Nozomu

    Published in Scientific reports (27-03-2024)
    “…The association between serum tumor necrosis factor receptor (TNFRs: TNFR1, TNFR2) levels and estimated glomerular filtration rate (eGFR) observed in patients…”
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    Circulating kidney injury molecule‐1 as a biomarker of renal parameters in diabetic kidney disease by Gohda, Tomohito, Kamei, Nozomu, Koshida, Takeo, Kubota, Mitsunobu, Tanaka, Kanako, Yamashita, Yoshinori, Adachi, Eri, Ichikawa, Saki, Murakoshi, Maki, Ueda, Seiji, Suzuki, Yusuke

    Published in Journal of diabetes investigation (01-03-2020)
    “…Aims/Introduction Urinary kidney injury molecule‐1 (KIM‐1) has been associated with proximal tubular damage in human and animal studies. Although it has been…”
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    Association between circulating tumor necrosis factor-related biomarkers and estimated glomerular filtration rate in type 2 diabetes by Kamei, Nozomu, Yamashita, Mami, Nishizaki, Yuji, Yanagisawa, Naotake, Nojiri, Shuko, Tanaka, Kanako, Yamashita, Yoshinori, Shibata, Terumi, Murakoshi, Maki, Suzuki, Yusuke, Gohda, Tomohito

    Published in Scientific reports (17-10-2018)
    “…Chronic inflammation plays a crucial role in the development/progression of diabetic kidney disease. The involvement of tumor necrosis factor (TNF)-related…”
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    Clinical predictive biomarkers for normoalbuminuric diabetic kidney disease by Gohda, Tomohito, Nishizaki, Yuji, Murakoshi, Maki, Nojiri, Shuko, Yanagisawa, Naotake, Shibata, Terumi, Yamashita, Mami, Tanaka, Kanako, Yamashita, Yoshinori, Suzuki, Yusuke, Kamei, Nozomu

    Published in Diabetes research and clinical practice (01-07-2018)
    “…A portion of patients with diabetes mellitus follow the progression of a non-albuminuria-based pathway; i.e., normoalbuminuric diabetic kidney disease…”
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    Progranulin deficiency attenuates tubulointerstitial injury in a mouse unilateral ureteral obstruction model by Adachi, Eri, Murakoshi, Maki, Shibata, Terumi, Shimozawa, Kenta, Sakuma, Hiroko, Kishida, Chiaki, Gohda, Tomohito, Suzuki, Yusuke

    Published in Experimental Animals (01-01-2024)
    “…Progranulin (PGRN) may have two opposing effects—inflammation and anti-inflammation—in different diseases. Although previous studies have reported that PGRN is…”
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  13. 13

    Progranulin and Its Receptor Predict Kidney Function Decline in Patients With Type 2 Diabetes by Murakoshi, Maki, Gohda, Tomohito, Sakuma, Hiroko, Shibata, Terumi, Adachi, Eri, Kishida, Chiaki, Ichikawa, Saki, Koshida, Takeo, Kamei, Nozomu, Suzuki, Yusuke

    Published in Frontiers in endocrinology (Lausanne) (01-04-2022)
    “…Progranulin (PGRN), a growth factor, is abundantly expressed in a broad range of tissues and cell types with pleiotropic functions including inflammation,…”
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    Development of an In-House EphA2 ELISA for Human Serum and Measurement of Circulating Levels of EphA2 in Hypertensive Patients with Renal Dysfunction by Murakoshi, Maki, Iwasawa, Takumi, Koshida, Takeo, Suzuki, Yusuke, Gohda, Tomohito, Kato, Kazunori

    Published in Diagnostics (Basel) (01-12-2022)
    “…Identifying novel biomarkers of kidney function in patients with chronic kidney disease (CKD) has strong clinical value as current measures have limitations…”
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    Aspartic acid supplementation ameliorates symptoms of diabetic kidney disease in mice by Ichikawa, Saki, Gohda, Tomohito, Murakoshi, Maki, Li, Zi, Adachi, Eri, Koshida, Takeo, Suzuki, Yusuke

    Published in FEBS open bio (01-06-2020)
    “…Diabetic kidney disease (DKD) is among the most common and serious complications of both type 1 and type 2 diabetes. In this study, we used KK/Ta‐Ins2Akita…”
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  17. 17

    Effect of tonsillectomy with steroid pulse therapy on circulating tumor necrosis factor receptors 1 and 2 in IgA nephropathy by Murakoshi, Maki, Gohda, Tomohito, Sonoda, Yuji, Suzuki, Hitoshi, Tomino, Yasuhiko, Horikoshi, Satoshi, Suzuki, Yusuke

    Published in Clinical and experimental nephrology (01-12-2017)
    “…Background High circulating levels of soluble tumor necrosis factor receptors (TNFRs: TNFR1, TNFR2) predict renal function decline in a variety of kidney…”
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    The sodium–glucose cotransporter 2 inhibitor tofogliflozin prevents diabetic kidney disease progression in type 2 diabetic mice by Li, Zi, Murakoshi, Maki, Ichikawa, Saki, Koshida, Takeo, Adachi, Eri, Suzuki, Chigure, Ueda, Seiji, Gohda, Tomohito, Suzuki, Yusuke

    Published in FEBS open bio (01-12-2020)
    “…Tofogliflozin may prevent glomerular (enlarged mesangial area, foot process effacement, podocyte loss) and tubulointerstitial damage (increased expression of…”
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