Search Results - "MURAKAMI, Yuko"
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miRNA-148a-3p Regulates Immunosuppression in DNA Mismatch Repair-Deficient Colorectal Cancer by Targeting PD-L1
Published in Molecular cancer research (01-06-2019)“…Immunotherapy against the interaction between programmed cell death 1/programmed cell death ligand 1 (PD-L1) has emerged as a promising strategy for colorectal…”
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Pi‐Class Glutathione S‐transferase (GSTP1)‐Selective Fluorescent Probes for Multicolour Imaging with Various Cancer‐Associated Enzymes
Published in Chembiochem : a European journal of chemical biology (04-11-2022)“…Pi‐class glutathione S‐transferase (GSTP1) is highly expressed in a wide variety of human cancer tissues compared to the corresponding normal counterpart…”
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A Covalent Inhibitor for Glutathione S‐Transferase Pi (GSTP1‐1) in Human Cells
Published in Chembiochem : a European journal of chemical biology (01-04-2019)“…Glutathione S‐transferase π (GSTP1‐1) is overexpressed in many types of cancer and is involved in drug resistance. Therefore, GSTP1‐1 is an important target in…”
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Non-perturbative determination of the Λ-parameter in the pure SU(3) gauge theory from the twisted gradient flow coupling
Published in The journal of high energy physics (01-12-2017)“…A bstract We evaluate the Λ-parameter in the M S ¯ scheme for the pure SU(3) gauge theory with the twisted gradient flow (TGF) method. A running coupling…”
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Neuron ID dataset facilitates neuronal annotation for whole-brain activity imaging of C. elegans
Published in BMC biology (19-03-2020)“…Annotation of cell identity is an essential process in neuroscience that allows comparison of cells, including that of neural activities across different…”
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Functional differences between wild‐type and mutant‐type BRCA1‐associated protein 1 tumor suppressor against malignant mesothelioma cells
Published in Cancer science (01-08-2015)“…Malignant mesothelioma (MM) shows inactivation of the BRCA1‐associated protein 1 (BAP1) gene. In this study, we found BAP1 mutations in 5 (26%) of the 19 cell…”
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A Cell-Based, Microplate Colorimetric Screen Identifies 7,8-Benzoflavone and Green Tea Gallate Catechins as Inhibitors of the Hepatitis C Virus
Published in Biological & pharmaceutical bulletin (2012)“…We describe a cell-based, microplate colorimetric screen for anti-hepatitis C virus (HCV) drugs that exploits the HCV-JFH1 viral culture system. Antiviral…”
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Selective estrogen receptor modulators inhibit hepatitis C virus infection at multiple steps of the virus life cycle
Published in Microbes and infection (01-01-2013)“…We screened for hepatitis C virus (HCV) inhibitors using the JFH-1 viral culture system and found that selective estrogen receptor modulators (SERMs), such as…”
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Circulating chromosome 19 miRNA cluster microRNAs in pregnant women with severe pre-eclampsia
Published in The journal of obstetrics and gynaecology research (01-10-2015)“…Aim To clarify the association between circulating chromosome 19 miRNA cluster (C19MC) microRNAs in maternal plasma and severe pre‐eclampsia. Method Maternal…”
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Statin suppresses Hippo pathway-inactivated malignant mesothelioma cells and blocks the YAP/CD44 growth stimulatory axis
Published in Cancer letters (28-01-2017)“…Abstract Malignant mesothelioma (MM) frequently exhibits Hippo signaling pathway inactivation (HPI) mainly due to NF2 and/or LATS2 mutations, which leads to…”
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Nucleolar protein PES1 is a marker of neuroblastoma outcome and is associated with neuroblastoma differentiation
Published in Cancer science (01-03-2015)“…Neuroblastoma (NB) is a childhood malignant tumor that arises from precursor cells of the sympathetic nervous system. Spontaneous regression is a phenomenon…”
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Dual effects of the Nrf2 inhibitor for inhibition of hepatitis C virus and hepatic cancer cells
Published in BMC cancer (25-06-2018)“…We previously showed that knockdown of nuclear factor E2-related factor 2 (Nrf2) resulted in suppression of hepatitis C virus (HCV) infection. In this study,…”
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microRNA-mediated resistance to hypoglycemia in the HepG2 human hepatoma cell line
Published in BMC cancer (15-09-2016)“…It is generally accepted that the energy resources of cancer cells rely on anaerobic metabolism or the glycolytic system, even if they have sufficient oxygen…”
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Design and synthesis of versatile GSTP1-specific fluorogenic substrates for the highly sensitive detection of GSTP1 activity in living cells
Published in Talanta (Oxford) (01-01-2023)“…Pi-class glutathione S-transferase (GSTP1) is a detoxification enzyme that is highly expressed in various types of cancer cells and is a promising target for…”
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Total synthesis of the elastin crosslinker (+)-desmopyridine
Published in Tetrahedron: asymmetry (15-12-2012)“…Desmopyridine, isolated from the acid hydrolysates of bovine ligamentum nuchae, is an elastin crosslinker and an amino acid that has a 3,4,5-trisubstituted…”
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Prominent steatosis with hypermetabolism of the cell line permissive for years of infection with hepatitis C virus
Published in PloS one (01-04-2014)“…Most of experiments for HCV infection have been done using lytic infection systems, in which HCV-infected cells inevitably die. Here, to elucidate metabolic…”
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Synthesis and LC-MS/MS analysis of desmosine-CH2, a potential internal standard for the degraded elastin biomarker desmosine
Published in Organic & biomolecular chemistry (28-12-2014)“…Desmosine-CH2, an analog of the elastic tissue degradation biomarker desmosine, can be regarded as a potential internal standard for precise quantification of…”
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Identification of a lysophosphatidylserine receptor on mast cells
Published in Biochemical and biophysical research communications (24-03-2006)“…Lysophosphatidyl- l-serine (lysoPS) is thought to be an immunological regulator because it dramatically augments the degranulation of rat peritoneal mast cells…”
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Claudin-4-adhesion signaling drives breast cancer metabolism and progression via liver X receptor β
Published in Breast cancer research : BCR (14-04-2023)“…Cell adhesion is indispensable for appropriate tissue architecture and function in multicellular organisms. Besides maintaining tissue integrity, cell adhesion…”
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Necklace-shaped Dimethylsiloxane Polymers Bearing a Polyhedral Oligomeric Silsesquioxane Cage Prepared by Polycondensation and Ring-opening Polymerization
Published in Chemistry letters (2012)“…A series of necklace-shaped dimethylsiloxane (DMS) polymers bearing a polyhedral oligomeric silsesquioxane (POSS) cage were synthesized from bifunctional POSS…”
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