Search Results - "MUNOZ, Jenifer"

CTNND1 is involved in germline predisposition to early-onset gastric cancer by affecting cell-to-cell interactions by Herrera-Pariente, Cristina, Bonjoch, Laia, Muñoz, Jenifer, Fernàndez, Guerau, Soares de Lima, Yasmin, Mahmood, Romesa, Cuatrecasas, Miriam, Ocaña, Teresa, Lopez-Prades, Sandra, Llargués-Sistac, Gemma, Domínguez-Rovira, Xavier, Llach, Joan, Luzko, Irina, Díaz-Gay, Marcos, Lazaro, Conxi, Brunet, Joan, Castillo-Manzano, Carmen, García-González, María Asunción, Lanas, Angel, Carrillo, Marta, Hernández San Gil, Raquel, Quintero, Enrique, Sala, Nuria, Llort, Gemma, Aguilera, Lara, Carot, Laura, Diez-Redondo, Pilar, Jover, Rodrigo, Ramon y Cajal, Teresa, Cubiella, Joaquín, Castells, Antoni, Balaguer, Francesc, Bujanda, Luis, Castellví-Bel, Sergi, Moreira, Leticia

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Identification of New Genes Involved in Germline Predisposition to Early-Onset Gastric Cancer by Herrera-Pariente, Cristina, Capó-García, Roser, Díaz-Gay, Marcos, Carballal, Sabela, Muñoz, Jenifer, Llach, Joan, Sánchez, Ariadna, Bonjoch, Laia, Arnau-Collell, Coral, Soares de Lima, Yasmin, Golubicki, Mariano, Jung, Gerhard, Lozano, Juan José, Castells, Antoni, Balaguer, Francesc, Bujanda, Luis, Castellví-Bel, Sergi, Moreira, Leticia

“…The genetic cause for several families with gastric cancer (GC) aggregation is unclear, with marked relevance in early-onset patients. We aimed to identify new…”
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Germline Mutations in FAF1 Are Associated With Hereditary Colorectal Cancer by Bonjoch, Laia, Franch-Expósito, Sebastià, Garre, Pilar, Belhadj, Sami, Muñoz, Jenifer, Arnau-Collell, Coral, Díaz-Gay, Marcos, Gratacós-Mulleras, Anna, Raimondi, Giulia, Esteban-Jurado, Clara, Soares de Lima, Yasmin, Herrera-Pariente, Cristina, Cuatrecasas, Miriam, Ocaña, Teresa, Castells, Antoni, Fillat, Cristina, Capellá, Gabriel, Balaguer, Francesc, Caldés, Trinidad, Valle, Laura, Castellví-Bel, Sergi

“…A significant proportion of colorectal cancer (CRC) cases have familial aggregation but little is known about the genetic factors that contribute to these…”
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Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study by Domingo, Enric, Freeman-Mills, Luke, Rayner, Emily, Glaire, Mark, Briggs, Sarah, Vermeulen, Louis, Fessler, Evelyn, Medema, Jan Paul, Boot, Arnoud, Morreau, Hans, van Wezel, Tom, Liefers, Gerrit-Jan, Lothe, Ragnhild A, Danielsen, Stine A, Sveen, Anita, Nesbakken, Arild, Zlobec, Inti, Lugli, Alessandro, Koelzer, Viktor H, Berger, Martin D, Castellví-Bel, Sergi, Muñoz, Jenifer, de Bruyn, Marco, Nijman, Hans W, Novelli, Marco, Lawson, Kay, Oukrif, Dahmane, Frangou, Eleni, Dutton, Peter, Tejpar, Sabine, Delorenzi, Mauro, Kerr, Rachel, Kerr, David, Tomlinson, Ian, Church, David N

“…Precision cancer medicine depends on defining distinct tumour subgroups using biomarkers that may occur at very modest frequencies. One such subgroup comprises…”
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Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer by Esteban-Jurado, Clara, Vila-Casadesús, Maria, Garre, Pilar, Lozano, Juan José, Pristoupilova, Anna, Beltran, Sergi, Muñoz, Jenifer, Ocaña, Teresa, Balaguer, Francesc, López-Cerón, Maria, Cuatrecasas, Miriam, Franch-Expósito, Sebastià, Piqué, Josep M., Castells, Antoni, Carracedo, Angel, Ruiz-Ponte, Clara, Abulí, Anna, Bessa, Xavier, Andreu, Montserrat, Bujanda, Luis, Caldés, Trinidad, Castellví-Bel, Sergi

“…Purpose: Colorectal cancer is an important cause of mortality in the developed world. Hereditary forms are due to germ-line mutations in APC , MUTYH , and the…”
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Prevalence of somatic mutl homolog 1 promoter hypermethylation in Lynch syndrome colorectal cancer by Moreira, Leticia, Muñoz, Jenifer, Cuatrecasas, Míriam, Quintanilla, Isabel, Leoz, Maria Liz, Carballal, Sabela, Ocaña, Teresa, López‐Cerón, María, Pellise, Maria, Castellví‐Bel, Sergi, Jover, Rodrigo, Andreu, Montserrat, Carracedo, Angel, Xicola, Rosa Maria, Llor, Xavier, Boland, Clement Richard, Goel, Ajay, Castells, Antoni, Balaguer, Francesc

“…BACKGROUND Colorectal cancers (CRCs) that have microsatellite instability (MSI) and mutL homolog 1 (MLH1) immunoloss are observed in 3 clinical scenarios:…”
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Germline mutations in WNK2 could be associated with serrated polyposis syndrome by Soares de Lima, Yasmin, Arnau-Collell, Coral, Muñoz, Jenifer, Herrera-Pariente, Cristina, Moreira, Leticia, Ocaña, Teresa, Díaz-Gay, Marcos, Franch-Expósito, Sebastià, Cuatrecasas, Miriam, Carballal, Sabela, Lopez-Novo, Anael, Moreno, Lorena, Fernàndez, Guerau, Díaz de Bustamante, Aranzazu, Peters, Sophia, Sommer, Anna K, Spier, Isabel, Te Paske, Iris B A W, van Herwaarden, Yasmijn J, Castells, Antoni, Bujanda, Luis, Capellà, Gabriel, Steinke-Lange, Verena, Mahmood, Khalid, Joo, JiHoon Eric, Arnold, Julie, Parry, Susan, Macrae, Finlay A, Winship, Ingrid M, Rosty, Christophe, Cubiella, Joaquin, Rodríguez-Alcalde, Daniel, Holinski-Feder, Elke, de Voer, Richarda, Buchanan, Daniel D, Aretz, Stefan, Ruiz-Ponte, Clara, Valle, Laura, Balaguer, Francesc, Bonjoch, Laia, Castellvi-Bel, Sergi

“…Patients with serrated polyposis syndrome (SPS) have multiple and/or large serrated colonic polyps and higher risk for colorectal cancer. SPS inherited genetic…”
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Evaluating the Potential of Polygenic Risk Score to Improve Colorectal Cancer Screening by Arnau-Collell, Coral, Díez-Villanueva, Anna, Bellosillo, Beatriz, Augé, Josep M, Muñoz, Jenifer, Guinó, Elisabet, Moreira, Leticia, Serradesanferm, Anna, Pozo, Àngels, Torà-Rocamora, Isabel, Bonjoch, Laia, Ibañez-Sanz, Gemma, Obon-Santacana, Mireia, Moratalla-Navarro, Ferran, Sanz-Pamplona, Rebeca, Márquez Márquez, Carmen, Rueda Miret, Rebeca, Pérez Berbegal, Rocio, Piquer Velasco, Gabriel, Hernández Rodríguez, Cristina, Grau, Jaume, Castells, Antoni, Borràs, Josep M, Bessa, Xavier, Moreno, Victor, Castellví-Bel, Sergi

“…Colorectal cancer has high incidence and associated mortality worldwide. Screening programs are recommended for men and women over 50. Intermediate screens…”
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The Fanconi anemia DNA damage repair pathway in the spotlight for germline predisposition to colorectal cancer by Esteban-Jurado, Clara, Franch-Expósito, Sebastià, Muñoz, Jenifer, Ocaña, Teresa, Carballal, Sabela, López-Cerón, Maria, Cuatrecasas, Miriam, Vila-Casadesús, Maria, Lozano, Juan José, Serra, Enric, Beltran, Sergi, Brea-Fernández, Alejandro, Ruiz-Ponte, Clara, Castells, Antoni, Bujanda, Luis, Garre, Pilar, Caldés, Trinidad, Cubiella, Joaquín, Balaguer, Francesc, Castellví-Bel, Sergi

“…Colorectal cancer (CRC) is one of the most common neoplasms in the world. Fanconi anemia (FA) is a very rare genetic disease causing bone marrow failure,…”
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Epigenome-Wide DNA Methylation Profiling of Normal Mucosa Reveals HLA-F Hypermethylation as a Biomarker Candidate for Serrated Polyposis Syndrome by Jung, Gerhard, Hernández-Illán, Eva, Lozano, Juan J., Sidorova, Julia, Muñoz, Jenifer, Okada, Yasuyuki, Quintero, Enrique, Hernandez, Goretti, Jover, Rodrigo, Carballal, Sabela, Cuatrecasas, Miriam, Moreno, Lorena, Diaz, Mireia, Ocaña, Teresa, Sánchez, Ariadna, Rivero, Liseth, Ortiz, Oswaldo, Llach, Joan, Castells, Antoni, Pellisé, Maria, Goel, Ajay, Batlle, Eduard, Balaguer, Francesc

“…Serrated polyposis syndrome (SPS) is associated with a high risk for colorectal cancer. Intense promoter hypermethylation is a frequent molecular finding in…”
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Using linkage studies combined with whole‐exome sequencing to identify novel candidate genes for familial colorectal cancer by Toma, Claudio, Díaz‐Gay, Marcos, Franch‐Expósito, Sebastià, Arnau‐Collell, Coral, Overs, Bronwyn, Muñoz, Jenifer, Bonjoch, Laia, Soares de Lima, Yasmin, Ocaña, Teresa, Cuatrecasas, Miriam, Castells, Antoni, Bujanda, Luis, Balaguer, Francesc, Cubiella, Joaquín, Caldés, Trinidad, Fullerton, Janice M., Castellví‐Bel, Sergi

“…Colorectal cancer (CRC) is a complex disorder for which the majority of the underlying germline predisposition factors remain still unidentified. Here, we…”
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Germline biallelic Mcm8 variants are associated with early-onset Lynch-like syndrome by Golubicki, Mariano, Bonjoch, Laia, Acuña-Ochoa, José G, Díaz-Gay, Marcos, Muñoz, Jenifer, Cuatrecasas, Miriam, Ocaña, Teresa, Iseas, Soledad, Mendez, Guillermo, Cisterna, Daniel, Schubert, Stephanie A, Nielsen, Maartje, van Wezel, Tom, Goldberg, Yael, Pikarsky, Eli, Robbio, Juan, Roca, Enrique, Castells, Antoni, Balaguer, Francesc, Antelo, Marina, Castellví-Bel, Sergi

“…Lynch syndrome is the most common cause of hereditary colorectal cancer (CRC), and it is characterized by DNA mismatch repair (MMR) deficiency. The term…”
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CTNND1 is involved in germline predisposition to early-onset gastric cancer by affecting cell-to-cell interactions by Herrera-Pariente, Cristina, Bonjoch, Laia, Muñoz, Jenifer, Fernàndez, Guerau, Soares de Lima, Yasmin, Mahmood, Romesa, Cuatrecasas, Miriam, Ocaña, Teresa, Lopez-Prades, Sandra, Llargués-Sistac, Gemma, Domínguez-Rovira, Xavier, Llach, Joan, Luzko, Irina, Díaz-Gay, Marcos, Lazaro, Conxi, Brunet, Joan, Castillo-Manzano, Carmen, García-González, María Asunción, Lanas, Angel, Carrillo, Marta, Hernández San Gil, Raquel, Quintero, Enrique, Sala, Nuria, Llort, Gemma, Aguilera, Lara, Carot, Laura, Diez-Redondo, Pilar, Jover, Rodrigo, Ramon y Cajal, Teresa, Cubiella, Joaquín, Castells, Antoni, Balaguer, Francesc, Bujanda, Luis, Castellví-Bel, Sergi, Moreira, Leticia

“…Background CDH1 and CTNNA1 remain as the main genes for hereditary gastric cancer. However, they only explain a small fraction of gastric cancer cases with…”
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MSH6 and MUTYH Deficiency Is a Frequent Event in Early-Onset Colorectal Cancer by GIRALDEZ, Maria Dolores, BALAGUER, Francesc, MOREIRA, Leticia, ENRIQUEZ-NAVASCUES, José Maria, BOLAND, C. Richard, GOEL, Ajay, CASTELLS, Antoni, CASTELLVI-BEL, Sergi, BUJANDA, Luis, CUATRECASAS, Miriam, MUNOZ, Jenifer, ALONSO-ESPINACO, Virginia, LARZABAL, Mikel, PETIT, Anna, GONZALO, Victoria, OCANA, Teresa

“…Early-onset colorectal cancer (CRC) is suggestive of a hereditary predisposition. Lynch syndrome is the most frequent CRC hereditary cause. The MUTYH gene has…”
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POLE and POLD1 screening in 155 patients with multiple polyps and early-onset colorectal cancer by Esteban-Jurado, Clara, Giménez-Zaragoza, David, Muñoz, Jenifer, Franch-Expósito, Sebastià, Álvarez-Barona, Miriam, Ocaña, Teresa, Cuatrecasas, Miriam, Carballal, Sabela, López-Cerón, María, Marti-Solano, Maria, Díaz-Gay, Marcos, van Wezel, Tom, Castells, Antoni, Bujanda, Luis, Balmaña, Judith, Gonzalo, Victoria, Llort, Gemma, Ruiz-Ponte, Clara, Cubiella, Joaquín, Balaguer, Francesc, Aligué, Rosa, Castellví-Bel, Sergi

“…Germline mutations in POLE and POLD1 have been shown to cause predisposition to colorectal multiple polyposis and a wide range of neoplasms, early-onset…”
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Unraveling the impact of a germline heterozygous POLD1 frameshift variant in serrated polyposis syndrome by Bonjoch, Laia, Soares de Lima, Yasmin, Díaz-Gay, Marcos, Dotti, Isabella, Muñoz, Jenifer, Moreira, Leticia, Carballal, Sabela, Ocaña, Teresa, Cuatrecasas, Miriam, Ortiz, Oswaldo, Castells, Antoni, Pellisé, Maria, Balaguer, Francesc, Salas, Azucena, Alexandrov, Ludmil B, Castellví-Bel, Sergi

“…Serrated polyposis syndrome (SPS) is one of the most frequent polyposis syndromes characterized by an increased risk for developing colorectal cancer (CRC)…”
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Antidiabetic Sterols from Peniocereus greggii Roots by Muñoz-Gómez, R. Jenifer, Rivero-Cruz, Isabel, Ovalle-Magallanes, Berenice, Linares, Edelmira, Bye, Robert, Tovar, Armando R, Noriega, Lilia G, Tovar-Palacio, Claudia, Mata, Rachel

“…The roots of the cactus Peniocereus greggii, which grows in Northern Mexico and in the south of Arizona, are highly valued by the Pima to treat diabetes and…”
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Comprehensive Genomic Characterization of Fifteen Early-Onset Lynch-Like Syndrome Colorectal Cancers by Golubicki, Mariano, Díaz-Gay, Marcos, Bonjoch, Laia, Franch-Expósito, Sebastià, Muñoz, Jenifer, Cuatrecasas, Miriam, Ocaña, Teresa, Iseas, Soledad, Mendez, Guillermo, Carballido, Marcela, Robbio, Juan, Cisterna, Daniel, Roca, Enrique, Castells, Antoni, Balaguer, Francesc, Castellví-Bel, Sergi, Antelo, Marina

“…Lynch-like syndrome (LLS) is an increasingly common clinical challenge with an underlying molecular basis mostly unknown. To shed light onto it, we focused on…”
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Germline and Somatic Whole-Exome Sequencing Identifies New Candidate Genes Involved in Familial Predisposition to Serrated Polyposis Syndrome by Soares de Lima, Yasmin, Arnau-Collell, Coral, Díaz-Gay, Marcos, Bonjoch, Laia, Franch-Expósito, Sebastià, Muñoz, Jenifer, Moreira, Leticia, Ocaña, Teresa, Cuatrecasas, Miriam, Herrera-Pariente, Cristina, Carballal, Sabela, Moreno, Lorena, Díaz de Bustamante, Aránzazu, Castells, Antoni, Bujanda, Luis, Cubiella, Joaquín, Rodríguez-Alcalde, Daniel, Balaguer, Francesc, Castellví-Bel, Sergi

“…The serrated polyposis syndrome (SPS) is the most common and yet underdiagnosed colorectal polyposis syndrome. It is characterized by multiple and/or large…”
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Identification of MYH Mutation Carriers in Colorectal Cancer: A Multicenter, Case-Control, Population-Based Study by Balaguer, Francesc, Castellví–Bel, Sergi, Castells, Antoni, Andreu, Montserrat, Muñoz, Jenifer, Gisbert, Javier P, Llor, Xavier, Jover, Rodrigo, de Cid, Rafael, Gonzalo, Victòria, Bessa, Xavier, Xicola, Rosa M, Pons, Elisenda, Alenda, Cristina, Payá, Artemio, Piqué, Josep M

“…Background & Aims: Whereas it has conclusively been demonstrated that biallelic MutY human homolog ( MYH ) mutations confer a significant risk for colorectal…”
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