Search Results - "MULLHAUPT, Beat"

Direct antiviral agent treatment of chronic hepatitis C results in rapid regression of transient elastography and fibrosis markers fibrosis‐4 score and aspartate aminotransferase‐platelet ratio index by Bachofner, Jacqueline A., Valli, Piero V., Kröger, Arne, Bergamin, Irina, Künzler, Patrizia, Baserga, Adriana, Braun, Dominique, Seifert, Burkhardt, Moncsek, Anja, Fehr, Jan, Semela, David, Magenta, Lorenzo, Müllhaupt, Beat, Terziroli Beretta‐Piccoli, Benedetta, Mertens, Joachim C.

“…Background Novel direct antiviral agents (DAA) targeting hepatitis C virus (HCV) have revolutionized the treatment of chronic hepatitis C infection (CHC)…”
Get full text

HEV ORF2 protein-antibody complex deposits are associated with glomerulonephritis in hepatitis E with reduced immune status by Leblond, Anne-Laure, Helmchen, Birgit, Ankavay, Maliki, Lenggenhager, Daniela, Jetzer, Jasna, Helmchen, Fritjof, Yurtsever, Hueseyin, Parrotta, Rossella, Healy, Marc E., Pöschel, Amiskwia, Markkanen, Enni, Semmo, Nasser, Ferrié, Martin, Cocquerel, Laurence, Seeger, Harald, Hopfer, Helmut, Müllhaupt, Beat, Gouttenoire, Jérôme, Moradpour, Darius, Gaspert, Ariana, Weber, Achim

“…Hepatitis E virus (HEV) infection, one of the most common forms of hepatitis worldwide, is often associated with extrahepatic, particularly renal,…”
Get full text

Genetic diversity of Echinococcus multilocularis and Echinococcus granulosus sensu lato in Kyrgyzstan: The A2 haplotype of E. multilocularis is the predominant variant infecting humans by Alvarez Rojas, Cristian A, Kronenberg, Philipp A, Aitbaev, Sezdbek, Omorov, Rakhatbek A, Abdykerimov, Kubanychbek K, Paternoster, Giulia, Müllhaupt, Beat, Torgerson, Paul, Deplazes, Peter

“…Alveolar and cystic echinococcosis (AE, CE) caused by E. multilocularis and E. granulosus s.l., respectively, are considered emerging zoonotic diseases in…”
Get full text

Real-world effectiveness and safety of glecaprevir/pibrentasvir therapy in patients with chronic hepatitis C virus infection in Switzerland by Müllhaupt, Beat, Semela, David, Ruckstuhl, Lisa, Magenta, Lorenzo, Clerc, Olivier, Torgler, Ralph, Negro, Francesco, Semmo, Nasser

“…In the era of pangenotypic treatment regimens against hepatitis C virus (HCV) infection, data from postmarketing observational studies are crucial to better…”
Get full text

Secondary sclerosing cholangitis as cause of persistent jaundice in patients with severe COVID‐19 by Bütikofer, Simon, Lenggenhager, Daniela, Wendel Garcia, Pedro D., Maggio, Ewerton M., Haberecker, Martina, Reiner, Cäcilia S., Brüllmann, Gregor, Buehler, Philipp K., Gubler, Christoph, Müllhaupt, Beat, Jüngst, Christoph, Morell, Bernhard

“…Background & Aims Little is known about cholestasis, including its most severe variant secondary sclerosing cholangitis (SSC), in critically ill patients with…”
Get full text

Epidemic cystic and alveolar echinococcosis in Kyrgyzstan: an analysis of national surveillance data by Paternoster, Giulia, Boo, Gianluca, Wang, Craig, Minbaeva, Gulnara, Usubalieva, Jumagul, Raimkulov, Kursanbek Mamasalievich, Zhoroev, Abdykadyr, Abdykerimov, Kubanychbek Kudaibergenovich, Kronenberg, Philipp Andreas, Müllhaupt, Beat, Furrer, Reinhard, Deplazes, Peter, Torgerson, Paul Robert

“…Human cystic and alveolar echinococcosis are among the priority neglected zoonotic diseases for which WHO advocates control. The incidence of both cystic…”
Get full text

Targeting senescent cholangiocytes and activated fibroblasts with B‐cell lymphoma‐extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout (Mdr2−/−) mice by Moncsek, Anja, Al‐Suraih, Mohammed S., Trussoni, Christy E., O'Hara, Steven P., Splinter, Patrick L., Zuber, Camille, Patsenker, Eleonora, Valli, Piero V., Fingas, Christian D., Weber, Achim, Zhu, Yi, Tchkonia, Tamar, Kirkland, James L., Gores, Gregory J., Müllhaupt, Beat, LaRusso, Nicholas F., Mertens, Joachim C.

“…Cholangiocyte senescence has been linked to primary sclerosing cholangitis (PSC). Persistent secretion of growth factors by senescent cholangiocytes leads to…”
Get full text

Outcome after Discontinuing Long-Term Benzimidazole Treatment in 11 Patients with Non-resectable Alveolar Echinococcosis with Negative FDG-PET/CT and Anti-EmII/3-10 Serology by Ammann, Rudolf W, Stumpe, Katrin D M, Grimm, Felix, Deplazes, Peter, Huber, Sabine, Bertogg, Kaja, Fischer, Dorothee R, Müllhaupt, Beat

“…Benzimidazoles are efficacious for treating non-resectable alveolar echinococcosis (AE), but their long-term parasitocidal (curative) effect is disputed. In…”
Get full text

The current and future burden of hepatitis B in Switzerland: a modelling study by Negro, Francesco, Müllhaupt, Beat, Semela, David, Blach, Sarah, Bruggmann, Philip, De Gottardi, Andrea, Dufour, Jean-Francois, Fraga, Montserrat, Galante, Antonio, Razavi, Homie, Vieira Barbosa, Joana, Razavi-Shearer, Devin

“…Chronic hepatitis B infection (defined as sustained detection of hepatitis B virus [HBV] surface antigen [HBsAg] protein in serum) is a leading cause of…”
Get full text

Liver Allograft Failure After Nivolumab Treatment—A Case Report With Systematic Literature Research by Gassmann, Dimitri, Weiler, Stefan, Mertens, Joachim C., Reiner, Cäcilia S., Vrugt, Bart, Nägeli, Mirjam, Mangana, Joanna, Müllhaupt, Beat, Jenni, Fabienne, Misselwitz, Benjamin

“…Orthotopic liver transplantation (OLT) is a potential curative treatment in patients with hepatocellular carcinoma (HCC); however, treatment options for…”
Get full text

Adaptation of iron transport and metabolism to acute high‐altitude hypoxia in mountaineers by Goetze, Oliver, Schmitt, Johannes, Spliethoff, Kerstin, Theurl, Igor, Weiss, Günter, Swinkels, Dorine W., Tjalsma, Harold, Maggiorini, Marco, Krayenbühl, Pierre, Rau, Monika, Fruehauf, Heiko, Wojtal, Kacper A., Müllhaupt, Beat, Fried, Michael, Gassmann, Max, Lutz, Thomas, Geier, Andreas

“…Human iron homeostasis is regulated by intestinal iron transport, hepatic hepcidin release, and signals from pathways that consume or supply iron. The aim of…”
Get full text

Microelimination of chronic hepatitis C in Switzerland: modelling the Swiss Hepatitis Strategy goals in eastern, western and northern regions by Rusch, Urs, Robbins, Sarah, Razavi, Homie, Vernazza, Pietro, Blach, Sarah, Bruggmann, Philip, Müllhaupt, Beat, Negro, Francesco, Semela, David

“…Direct-acting antiviral agents have revolutionised hepatitis C treatment. In 2014, the Swiss Hepatitis Strategy was developed to eliminate hepatitis C virus…”
Get full text

Management of biliary obstruction in patients with newly diagnosed alveolar echinococcosis: a Swiss retrospective cohort study by Müller, Sandra, Ghafoor, Soleen, Meyer zu Schwabedissen, Cordula, Grimm, Felix, Murray, Fritz Ruprecht, Husmann, Lars, Stanek, Nadine, Deplazes, Peter, Schlag, Christoph, Kremer, Andreas E., Gubler, Christoph, Reiner, Cäcilia S., Semela, David, Müllhaupt, Beat, Deibel, Ansgar

“…BACKGROUND AND STUDY AIMS: Alveolar echinococcosis, an orphan zoonosis affecting the liver, is of increasing concern worldwide. Most symptomatic cases present…”
Get full text

Association between environmental and climatic risk factors and the spatial distribution of cystic and alveolar echinococcosis in Kyrgyzstan by Paternoster, Giulia, Boo, Gianluca, Flury, Roman, Raimkulov, Kursanbek M, Minbaeva, Gulnara, Usubalieva, Jumagul, Bondarenko, Maksym, Müllhaupt, Beat, Deplazes, Peter, Furrer, Reinhard, Torgerson, Paul R

“…Background Cystic and alveolar echinococcosis (CE and AE) are neglected tropical diseases caused by Echinococcus granulosus sensu lato and E. multilocularis,…”
Get full text

Impact of geographic origin on access to therapy and therapy outcomes in the Swiss Hepatitis C Cohort Study by Brezzi, Matteo, Bertisch, Barbara, Roelens, Maroussia, Moradpour, Darius, Terziroli Beretta-Piccoli, Benedetta, Semmo, Nasser, Müllhaupt, Beat, Semela, David, Negro, Francesco, Keiser, Olivia

“…Late diagnosis and treatment may increase morbidity and mortality among persons with hepatitis C virus (HCV) infection. We included all participants of the…”
Get full text

Increasing prevalence of obesity and diabetes among patients evaluated for liver transplantation in a Swiss tertiary referral center: a 10-year retrospective analysis by Kasmi, Sophie, Artru, Florent, Barbosa, Joana Vieira, Deibel, Ansgar Rudolf, Favre, Lucie, Peuble, Claire, Saouli, Anne-Catherine, Goossens, Nicolas, Müllhaupt, Beat, Pascual, Manuel, Moradpour, Darius, Vionnet, Julien, Fraga, Montserrat

“…Non-alcoholic fatty liver disease (NAFLD) is now the first cause of chronic liver disease in developed countries. We aimed to assess trends in the prevalence…”
Get full text

IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes by Bochud, Pierre-Yves, Bibert, Stéphanie, Kutalik, Zoltán, Patin, Etienne, Guergnon, Julien, Nalpas, Bertrand, Goossens, Nicolas, Kuske, Lorenz, Müllhaupt, Beat, Gerlach, Tillman, Heim, Markus H., Moradpour, Darius, Cerny, Andreas, Malinverni, Raffaele, Regenass, Stephan, Dollenmaier, Guenter, Hirsch, Hans, Martinetti, Gladys, Gorgiewski, Meri, Bourlière, Marc, Poynard, Thierry, Theodorou, Ioannis, Abel, Laurent, Pol, Stanislas, Dufour, Jean-François, Negro, Francesco

“…Genetic polymorphisms near IL28B are associated with spontaneous and treatment‐induced clearance of hepatitis C virus (HCV), two processes that require the…”
Get full text

Serum IP-10 levels and increased DPPIV activity are linked to circulating CXCR3+ T cells in cholestatic HCV patients by Rau, Monika, Schmitt, Johannes, Berg, Thomas, Kremer, Andreas E, Stieger, Bruno, Spanaus, Katharina, Bengsch, Bertram, Romero, Marta R, Marin, Jose J, Keitel, Verena, Klinker, Hartwig, Tony, Hans-Peter, Müllhaupt, Beat, Geier, Andreas

“…Serum interferon-gamma-inducible protein-10 (IP-10) is elevated in cholestatic liver diseases and predicts response to antiviral therapy in patients with…”
Get full text

A systematic review and meta‐analysis of HCV clearance by Gauthiez, Emeline, Habfast‐Robertson, Ines, Rüeger, Sina, Kutalik, Zoltan, Aubert, Vincent, Berg, Thomas, Cerny, Andreas, Gorgievski, Meri, George, Jacob, Heim, Markus H., Malinverni, Raffaele, Moradpour, Darius, Müllhaupt, Beat, Negro, Francesco, Semela, David, Semmo, Nasser, Villard, Jean, Bibert, Stéphanie, Bochud, Pierre‐Yves

“…While hepatitis C exemplifies the role of host genetics in infectious diseases outcomes, there is no comprehensive overview of polymorphisms influencing…”
Get full text

Determinants of Advanced Liver Fibrosis in Adult Patients After Fontan Palliation: Usefulness of Ultrasound Transient Elastography by Bütikofer, Simon, Greutmann-Yantiri, Mehtap, Gubler, Christoph, Reiner, Cecilia, Alkadhi, Hatem, Pfammatter, Thomas, Puippe, Gilbert, Santos Lopes, Bruno, Possner, Mathias, Bonassin, Francesca, Meier, Lukas, Babic, Daniela, Attenhofer Jost, Christine, Jüngst, Christoph, Müllhaupt, Beat, Bernsmeier, Christine, Schwerzmann, Markus, Tobler, Daniel, Lenggenhager, Daniela, Marques Maggio, Ewerton, Greutmann, Matthias

“…Fontan-associated liver disease is an increasing concern. Our aim was to assess prevalence and predictors of advanced liver fibrosis with a specific focus on…”
Get full text