Search Results - "MULLEN, C"

Genome-Wide Maps of m6A circRNAs Identify Widespread and Cell-Type-Specific Methylation Patterns that Are Distinct from mRNAs by Zhou, Chan, Molinie, Benoit, Daneshvar, Kaveh, Pondick, Joshua V., Wang, Jinkai, Van Wittenberghe, Nicholas, Xing, Yi, Giallourakis, Cosmas C., Mullen, Alan C.

“…N6-methyladenosine (m6A) is the most abundant internal modification of mRNAs and is implicated in all aspects of post-transcriptional RNA metabolism. However,…”
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Master Transcription Factors Determine Cell-Type-Specific Responses to TGF-β Signaling by Mullen, Alan C., Orlando, David A., Newman, Jamie J., Lovén, Jakob, Kumar, Roshan M., Bilodeau, Steve, Reddy, Jessica, Guenther, Matthew G., DeKoter, Rodney P., Young, Richard A.

“…Transforming growth factor beta (TGF-β) signaling, mediated through the transcription factors Smad2 and Smad3 (Smad2/3), directs different responses in…”
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Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells by Sigova, Alla A., Mullen, Alan C., Molinie, Benoit, Gupta, Sumeet, Orlando, David A., Guenther, Matthew G., Almada, Albert E., Lin, Charles, Sharp, Phillip A., Giallourakis, Cosmas C., Young, Richard A.

“…Many long noncoding RNA (lncRNA) species have been identified in mammalian cells, but the genomic origin and regulation of these molecules in individual cell…”
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lncRNA DIGIT and BRD3 protein form phase-separated condensates to regulate endoderm differentiation by Daneshvar, Kaveh, Ardehali, M. Behfar, Klein, Isaac A., Hsieh, Fu-Kai, Kratkiewicz, Arcadia J., Mahpour, Amin, Cancelliere, Sabrina O. L., Zhou, Chan, Cook, Brett M., Li, Wenyang, Pondick, Joshua V., Gupta, Sweta K., Moran, Sean P., Young, Richard A., Kingston, Robert E., Mullen, Alan C.

“…Cooperation between DNA, RNA and protein regulates gene expression and controls differentiation through interactions that connect regions of nucleic acids and…”
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Surgical Ablation of Atrial Fibrillation during Mitral-Valve Surgery by Gillinov, A. Marc, Gelijns, Annetine C, Parides, Michael K, DeRose, Joseph J, Moskowitz, Alan J, Voisine, Pierre, Ailawadi, Gorav, Bouchard, Denis, Smith, Peter K, Mack, Michael J, Acker, Michael A, Mullen, John C, Rose, Eric A, Chang, Helena L, Puskas, John D, Couderc, Jean-Philippe, Gardner, Timothy J, Varghese, Robin, Horvath, Keith A, Bolling, Steven F, Michler, Robert E, Geller, Nancy L, Ascheim, Deborah D, Miller, Marissa A, Bagiella, Emilia, Moquete, Ellen G, Williams, Paula, Taddei-Peters, Wendy C, O'Gara, Patrick T, Blackstone, Eugene H, Argenziano, Michael

“…In this trial, patients with atrial fibrillation undergoing mitral-valve surgery were assigned to surgical ablation of AF or no ablation. At 6 and 12 months,…”
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Partnerships between operators and public transport authorities. Working practices in relational contracting and collaborative partnerships by Hrelja, Robert, Rye, Tom, Mullen, Caroline

“…Recent research on public transport has seen increasing focus on issues like coordination, collaboration and steering in complex governance settings. One of…”
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TGFβ signalling acts as a molecular brake of myoblast fusion by Melendez, Julie, Sieiro, Daniel, Salgado, David, Morin, Valérie, Dejardin, Marie-Julie, Zhou, Chan, Mullen, Alan C., Marcelle, Christophe

“…Fusion of nascent myoblasts to pre-existing myofibres is critical for skeletal muscle growth and repair. The vast majority of molecules known to regulate…”
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Bone cell mechanosensation of fluid flow stimulation: a fluid–structure interaction model characterising the role integrin attachments and primary cilia by Vaughan, T. J., Mullen, C. A., Verbruggen, S. W., McNamara, L. M.

“…Load-induced fluid flow acts as an important biophysical signal for bone cell mechanotransduction in vivo, where the mechanical environment is thought to be…”
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Hippo Tips the TGF-β Scale in Favor of Pluripotency by Mullen, Alan C.

“…How TGF-β signaling switches from enforcing pluripotency to promoting mesendodermal differentiation remains an open question. Recently in Cell Reports, Beyer…”
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Effect of Obesity on Short- and Long-term Mortality Postcoronary Revascularization: A Meta-analysis by Oreopoulos, Antigone, Padwal, Raj, Norris, Colleen M, Mullen, John C, Pretorius, Victor, Kalantar-Zadeh, Kamyar

“…Objective: Overweight and obesity are often assumed to be risk factors for postprocedural mortality in patients with coronary artery disease (CAD). However,…”
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Osteocyte differentiation and the formation of an interconnected cellular network in vitro by Mc Garrigle, M J, Mullen, C A, Haugh, M G, Voisin, M C, McNamara, L M

“…Extracellular matrix (ECM) stiffness and cell density can regulate osteoblast differentiation in two dimensional environments. However, it is not yet known how…”
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DIGIT Is a Conserved Long Noncoding RNA that Regulates GSC Expression to Control Definitive Endoderm Differentiation of Embryonic Stem Cells by Daneshvar, Kaveh, Pondick, Joshua V., Kim, Byeong-Moo, Zhou, Chan, York, Samuel R., Macklin, Jillian A., Abualteen, Ameed, Tan, Bo, Sigova, Alla A., Marcho, Chelsea, Tremblay, Kimberly D., Mager, Jesse, Choi, Michael Y., Mullen, Alan C.

“…Long noncoding RNAs (lncRNAs) exhibit diverse functions, including regulation of development. Here, we combine genome-wide mapping of SMAD3 occupancy with…”
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High-capacity sample multiplexing for single cell chromatin accessibility profiling by Booth, Gregory T, Daza, Riza M, Srivatsan, Sanjay R, McFaline-Figueroa, José L, Gladden, Rula Green, Mullen, Andrew C, Furlan, Scott N, Shendure, Jay, Trapnell, Cole

“…Single-cell chromatin accessibility has emerged as a powerful means of understanding the epigenetic landscape of diverse tissues and cell types, but profiling…”
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Producing Stable Pyrolysis Liquids from the Oil-Seed Presscakes of Mustard Family Plants: Pennycress (Thlaspi arvense L.) and Camelina (Camelina sativa) by Boateng, A. A, Mullen, C. A, Goldberg, N. M

“…Natural oil from non-food oil seeds, such as camelina, jatropha, and pennycress, is increasingly becoming the feedstock of choice for biodiesel production…”
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Osteocyte differentiation is regulated by extracellular matrix stiffness and intercellular separation by Mullen, C.A., Haugh, M.G., Schaffler, M.B., Majeska, R.J., McNamara, L.M.

“…Osteocytes are terminally differentiated bone cells, derived from osteoblasts, which are vital for the regulation of bone formation and resorption. ECM…”
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Transcriptomic Signatures of End-Stage Human Dilated Cardiomyopathy Hearts with and without Left Ventricular Assist Device Support by Parikh, Mihir, Shah, Saumya, Basu, Ratnadeep, Famulski, Konrad S, Kim, Daniel, Mullen, John C, Halloran, Philip F, Oudit, Gavin Y

“…Left ventricular assist device (LVAD) use in patients with dilated cardiomyopathy (DCM) can lead to a differential response in the LV and right ventricle (RV),…”
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A Prospective Multi-Institutional Cohort Study of Mediastinal Infections After Cardiac Operations by Perrault, Louis P., Kirkwood, Katherine A., Chang, Helena L., Mullen, John C., Gulack, Brian C., Argenziano, Michael, Gelijns, Annetine C., Ghanta, Ravi K., Whitson, Bryan A., Williams, Deborah L., Sledz-Joyce, Nancy M., Lima, Brian, Greco, Giampaolo, Fumakia, Nishit, Rose, Eric A., Puskas, John D., Blackstone, Eugene H., Weisel, Richard D., Bowdish, Michael E.

“…Mediastinal infections are a potentially devastating complication of cardiac operations. This study analyzed the frequency, risk factors, and perioperative…”
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Impact of Left Ventricular to Mitral Valve Ring Mismatch on Recurrent Ischemic Mitral Regurgitation After Ring Annuloplasty by Capoulade, Romain, Zeng, Xin, Overbey, Jessica R, Ailawadi, Gorav, Alexander, John H, Ascheim, Deborah, Bowdish, Michael, Gelijns, Annetine C, Grayburn, Paul, Kron, Irving L, Levine, Robert A, Mack, Michael J, Melnitchouk, Serguei, Michler, Robert E, Mullen, John C, O’Gara, Patrick, Parides, Michael K, Smith, Peter, Voisine, Pierre, Hung, Judy

“…BACKGROUND:In ischemic mitral regurgitation (IMR), ring annuloplasty is associated with a significant rate of recurrent MR. Ring size is based on intertrigonal…”
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Myeloid sarcoma of uterine cervix: A case report with review of the literature by Mullen, C., Beverstock, S., Roddie, H., Campbell, V.L., Al-Qsous, W.

“…•Myeloid sarcoma of uterine cervix is very uncommon and can be the initial presentation of acute myeloid leukaemia.•Myeloid sarcoma can mimic other malignant…”
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Cell morphology and focal adhesion location alters internal cell stress by Mullen, C. A., Vaughan, T. J., Voisin, M. C., Brennan, M. A., Layrolle, P., McNamara, L. M.

“…Extracellular mechanical cues have been shown to have a profound effect on osteogenic cell behaviour. However, it is not known precisely how these cues alter…”
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