Search Results - "MULLEN, A. B"

The efficacy of aerosol treatment with non-ionic surfactant vesicles containing amphotericin B in rodent models of leishmaniasis and pulmonary aspergillosis infection by Alsaadi, M., Italia, J.L., Mullen, A.B., Kumar, M.N.V. Ravi, Candlish, A.A., Williams, R.A.M., Shaw, C.D., Al Gawhari, F., Coombs, G.H., Wiese, M., Thomson, A.H., Puig-Sellart, M., Wallace, J., Sharp, A., Wheeler, L., Warn, P., Carter, K.C.

“…Amphotericin B (AMB) is used to treat both fungal and leishmanial infections, which are of major significance to human health. Clinical use of free AMB is…”
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Resistance of Leishmania donovani to Sodium Stibogluconate Is Related to the Expression of Host and Parasite γ-Glutamylcysteine Synthetase by CARTER, K. C, HUTCHISON, S, HENRIQUEZ, F. L, LEGARE, D, OUELLETTE, M, ROBERTS, C. W, MULLEN, A. B

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The In Vivo Susceptibility of Leishmania donovani to Sodium Stibogluconate Is Drug Specific and Can Be Reversed by Inhibiting Glutathione Biosynthesis by CARTER, K. C, SUNDAR, S, SPICKETT, C, PEREIRA, O. C, MULLEN, A. B

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Vaccination with Recombinant Leishmania donovani Gamma-Glutamylcysteine Synthetase Fusion Protein Protects Against L. donovani Infection by Henriquez, F. L, Campbell, S. A, Roberts, C. W, Mullen, A. B, Burchmore, R, Carter, K. C

“…Visceral leishmaniasis presents a serious health threat in many parts of the world. There is, therefore, an urgent need for an approved vaccine for clinical…”
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Pharmacokinetics, Toxicities, and Efficacies of Sodium Stibogluconate Formulations after Intravenous Administration in Animals by NIETO, J, ALVAR, J, MULLEN, A. B, CARTER, K. C, RODRIGUEZ, C, ANDRES, M. I, SAN ANDRES, M. D, BAILLIE, A. J, GONZALEZ, F

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Comparative assessment of a DNA and protein Leishmania donovani gamma glutamyl cysteine synthetase vaccine to cross-protect against murine cutaneous leishmaniasis caused by L. major or L. mexicana infection by Campbell, S.A, Alawa, J, Doro, B, Henriquez, F.L, Roberts, C.W, Nok, A, Alawa, C.B.I, Alsaadi, M, Mullen, A.B, Carter, K.C

“…Highlights ► L. donovani gamma-glutamyl cysteine synthetase (γGCS) DNA and protein vaccine to cross protect against L. major and L. mexicana determined. ►…”
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Comparison of the efficacies of various formulations of amphotericin B against murine visceral leishmaniasis by MULLEN, A. B, CARTER, K. C, BAILLIE, A. J

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DNA vaccination against the parasite enzyme gamma-glutamylcysteine synthetase confers protection against Leishmania donovani infection by Carter, K.C, Henriquez, F.L, Campbell, S.A, Roberts, C.W, Nok, A, Mullen, A.B, McFarlane, E

“…Abstract In this study the potential of using Leishmania donovani gamma-glutamylcysteine synthetase (glutamate-cysteine ligase, γ-GCS) as a rational target for…”
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Sodium stibogluconate resistance in Leishmania donovani correlates with greater tolerance to macrophage antileishmanial responses and trivalent antimony therapy by Carter, K C, Hutchison, S, Boitelle, A, Murray, H W, Sundar, S, Mullen, A B

“…Co-treatment of mice infected with different strains of Leishmania donovani with a non-ionic surfactant vesicle formulation of buthionine sulfoximine…”
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A comparison of medication adherence/persistence for asthma and chronic obstructive pulmonary disease in the United Kingdom by Covvey, J R, Mullen, A B, Ryan, M, Steinke, D T, Johnston, B F, Wood, F T, Boyter, A C

“…To describe and compare adherence and persistence with maintenance therapies in patients with asthma or chronic obstructive pulmonary disease (COPD) in the…”
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Visceral Leishmaniasis in the BALB/c Mouse: A Comparison of the Efficacy of a Nonionic Surfactant Formulation of Sodium Stibogluconate with Those of Three Proprietary Formulations of Amphotericin B by MULLEN, A. B, BAILLIE, A. J, CARTER, K. C

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Development of an obstetrics triage tool for clinical pharmacists by Covvey, J. R., Grant, J., Mullen, A. B.

“…Summary What is known and objectives Obstetrics services are a high‐throughput and high‐risk environment poised for pharmacist involvement, but determining how…”
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Efficacies of vesicular and free sodium stibogluconate formulations against clinical isolates of Leishmania donovani by CARTER, K. C, MULLEN, A. B, SUNDAR, S, KENNEY, R. T

“…In this study, the in vitro and in vivo efficacies of free sodium stibogluconate (SSG) and a nonionic surfactant vesicular formulation of SSG (SSG-NIV) against…”
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Efficacy of an anti-fertility vaccine based on mammalian gonadotrophin releasing hormone (GnRH-I)—a histological comparison in male animals by Ferro, V.A, Khan, M.A.H, McAdam, D, Colston, A, Aughey, E, Mullen, A.B, Waterston, M.M, Harvey, M.J.A

“…A N-terminal modified gonadotrophin releasing hormone (GnRH-I, tetanus toxoid-CHWSYGLRPG-NH 2) conjugate was evaluated histologically in a number of male…”
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Translation of an experimental oral vaccine formulation into a commercial product by Carter, K.C., Ferro, V.A., Alexander, J., Mullen, A.B.

“…An effective experimental vaccine may fail to become a therapeutic reality for a number of scientific, regulatory or commercial reasons. In this review, we…”
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Comparison of the efficacy of free and non-ionic-surfactant vesicular formulations of paromomycin in a murine model of visceral leishmaniasis by WILLIAMS, D, MULLEN, A. B, BAILLIE, A. J, CARTER, K. C

“…Non-ionic-surfactant vesicular (NIV) formulations of paromomycin have been tested in-vitro and in-vivo for their activity against Leishmania donovani…”
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Isatin thiosemicarbazones promote honeycomb structure formation in spin-coated polymer films: concentration effect and release studies by Fernández-Luna, V. García, Mallinson, D., Alexiou, P., Khadra, I., Mullen, A. B., Pelecanou, M., Sagnou, M., Lamprou, D. A.

“…Formation of ordered porous polymer films is one of the techniques currently under investigation for its potential for the manufacturing of coatings with…”
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Directly Administered Antiretroviral Therapy in Methadone Clinics Is Associated with Improved HIV Treatment Outcomes, Compared with Outcomes among Concurrent Comparison Groups by Lucas, Gregory M., Mullen, B. Anna, Weidle, Paul J., Hader, Shannon, McCaul, Mary E., Moore, Richard D.

“…Background. Directly administered antiretroviral therapy (DAART) in methadone clinics has the potential to improve treatment outcomes for human…”
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The cured immune phenotype achieved by treatment of visceral leishmaniasis in the BALB/c mouse with a nonionic surfactant vesicular formulation of sodium stibogluconate does not protect against reinfection by Carter, K C, Baillie, A J, Mullen, A B

“…Single-dose treatment with sodium stibogluconate solution (SSG) and treatment with a nonionic surfactant vesicular formulation of sodium stibogluconate…”
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Qualitative analysis of microbial contamination of inhalers by Mabbott, F.A, Mullen, A.B, Smith, A, Smith, G, Boyter, A.C

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