Search Results - "MUKHERJEE, Bhramar"

Associations of cumulative exposure to heavy metal mixtures with obesity and its comorbidities among U.S. adults in NHANES 2003–2014 by Wang, Xin, Mukherjee, Bhramar, Park, Sung Kyun

“…Some heavy metals (e.g., arsenic, cadmium, lead, mercury) have been associated with obesity and obesity comorbidities. The analytical approach for those…”
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Construction of environmental risk score beyond standard linear models using machine learning methods: application to metal mixtures, oxidative stress and cardiovascular disease in NHANES by Park, Sung Kyun, Zhao, Zhangchen, Mukherjee, Bhramar

“…There is growing concern of health effects of exposure to pollutant mixtures. We initially proposed an Environmental Risk Score (ERS) as a summary measure to…”
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Repeated measures of inflammation and oxidative stress biomarkers in preeclamptic and normotensive pregnancies by Ferguson, Kelly K., PhD, Meeker, John D., ScD, McElrath, Thomas F., MD, PhD, Mukherjee, Bhramar, PhD, Cantonwine, David E., PhD

“…Background Preeclampsia is a prevalent and enigmatic disease, in part characterized by poor remodeling of the spiral arteries. However, preeclampsia does not…”
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Application of an analytical framework for multivariate mediation analysis of environmental data by Aung, Max T., Song, Yanyi, Ferguson, Kelly K., Cantonwine, David E., Zeng, Lixia, McElrath, Thomas F., Pennathur, Subramaniam, Meeker, John D., Mukherjee, Bhramar

“…Diverse toxicological mechanisms may mediate the impact of environmental toxicants (phthalates, phenols, polycyclic aromatic hydrocarbons, and metals) on…”
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Longitudinal trends in perfluoroalkyl and polyfluoroalkyl substances among multiethnic midlife women from 1999 to 2011: The Study of Women′s Health Across the Nation by Ding, Ning, Harlow, Siobán D., Batterman, Stuart, Mukherjee, Bhramar, Park, Sung Kyun

“…•Serum concentrations of legacy compounds decreased significantly in midlife women.•PFNA serum concentrations increased, and detection rates of PFDeA and PFUA…”
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A Fast and Accurate Method for Genome-Wide Time-to-Event Data Analysis and Its Application to UK Biobank by Bi, Wenjian, Fritsche, Lars G., Mukherjee, Bhramar, Kim, Sehee, Lee, Seunggeun

“…With increasing biobanking efforts connecting electronic health records and national registries to germline genetics, the time-to-event data analysis has…”
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Incidence and survival of inflammatory breast cancer between 1973 and 2015 in the SEER database by Abraham, Hannah Grace, Xia, Yaoxuan, Mukherjee, Bhramar, Merajver, Sofia Diana

“…Purpose Inflammatory breast cancer (IBC) is an aggressive variant characterized by erythema, edema, and “peau d’orange” of the skin progressing within 6…”
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Urinary phthalate metabolites and biomarkers of oxidative stress in pregnant women: a repeated measures analysis by Ferguson, Kelly K, McElrath, Thomas F, Chen, Yin-Hsiu, Mukherjee, Bhramar, Meeker, John D

“…Phthalate exposure occurs readily in the environment and has been associated with an array of health end points, including adverse birth outcomes. Some of…”
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Exploiting Gene-Environment Independence for Analysis of Case-Control Studies: An Empirical Bayes-Type Shrinkage Estimator to Trade-Off between Bias and Efficiency by Mukherjee, Bhramar, Chatterjee, Nilanjan

“…Standard prospective logistic regression analysis of case-control data often leads to very imprecise estimates of gene-environment interactions due to small…”
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Variability in urinary phthalate metabolite levels across pregnancy and sensitive windows of exposure for the risk of preterm birth by Ferguson, Kelly K., McElrath, Thomas F., Ko, Yi-An, Mukherjee, Bhramar, Meeker, John D.

“…Preterm birth is a significant public health problem, affecting over 1 in 10 live births and contributing largely to infant mortality and morbidity. Everyday…”
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Association of Polygenic Risk Scores for Multiple Cancers in a Phenome-wide Study: Results from The Michigan Genomics Initiative by Fritsche, Lars G., Gruber, Stephen B., Wu, Zhenke, Schmidt, Ellen M., Zawistowski, Matthew, Moser, Stephanie E., Blanc, Victoria M., Brummett, Chad M., Kheterpal, Sachin, Abecasis, Gonçalo R., Mukherjee, Bhramar

“…Health systems are stewards of patient electronic health record (EHR) data with extraordinarily rich depth and breadth, reflecting thousands of diagnoses and…”
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Urinary concentrations of phenols in association with biomarkers of oxidative stress in pregnancy: Assessment of effects independent of phthalates by Ferguson, Kelly K., Lan, Zhao, Yu, Youfei, Mukherjee, Bhramar, McElrath, Thomas F., Meeker, John D.

“…Maternal exposure to environmental phenols is common in pregnancy and has been linked to preterm birth, preeclampsia, and reduced fetal growth. One potential…”
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Repeated measures of urinary oxidative stress biomarkers during pregnancy and preterm birth by Ferguson, Kelly K., PhD, McElrath, Thomas F., MD, PhD, Chen, Yin-Hsiu, MS, Loch-Caruso, Rita, PhD, Mukherjee, Bhramar, PhD, Meeker, John D., ScD

“…Objective The purpose of this study was to investigate oxidative stress as a mechanism of preterm birth in human subjects; we examined associations between…”
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Does Information on Blood Heavy Metals Improve Cardiovascular Mortality Prediction? by Wang, Xin, Mukherjee, Bhramar, Park, Sung Kyun

“…Background To evaluate whether blood markers of lead, cadmium, and mercury can improve prediction for cardiovascular disease (CVD) mortality when added…”
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The emerging landscape of health research based on biobanks linked to electronic health records: Existing resources, statistical challenges, and potential opportunities by Beesley, Lauren J., Salvatore, Maxwell, Fritsche, Lars G., Pandit, Anita, Rao, Arvind, Brummett, Chad, Willer, Cristen J., Lisabeth, Lynda D., Mukherjee, Bhramar

“…Biobanks linked to electronic health records provide rich resources for health‐related research. With improvements in administrative and informatics…”
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Incorporating functional annotation with bilevel continuous shrinkage for polygenic risk prediction by Zhuang, Yongwen, Kim, Na Yeon, Fritsche, Lars G, Mukherjee, Bhramar, Lee, Seunggeun

“…Genetic variants can contribute differently to trait heritability by their functional categories, and recent studies have shown that incorporating functional…”
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Incorporating false negative tests in epidemiological models for SARS-CoV-2 transmission and reconciling with seroprevalence estimates by Bhattacharyya, Rupam, Kundu, Ritoban, Bhaduri, Ritwik, Ray, Debashree, Beesley, Lauren J., Salvatore, Maxwell, Mukherjee, Bhramar

“…Susceptible-Exposed-Infected-Removed (SEIR)-type epidemiologic models, modeling unascertained infections latently, can predict unreported cases and deaths…”
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Per- and Polyfluoroalkyl Substances and Incident Hypertension in Multi-Racial/Ethnic Women: The Study of Women's Health Across the Nation by Ding, Ning, Karvonen-Gutierrez, Carrie A., Mukherjee, Bhramar, Calafat, Antonia M., Harlow, Siobán D., Park, Sung Kyun

“…Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are ubiquitous synthetic chemicals that may disrupt blood pressure controls; however, human evidence to…”
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Urinary metal mixtures and longitudinal changes in glucose homeostasis: The Study of Women’s Health Across the Nation (SWAN) by Wang, Xin, Mukherjee, Bhramar, Karvonen-Gutierrez, Carrie A., Herman, William H., Batterman, Stuart, Harlow, Siobán D., Park, Sung Kyun

“…•Urinary zinc was positively and molybdenum was inversely associated with HOMA-IR at baseline.•Urinary zinc was inversely associated with HOMA-β at…”
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Maternal blood metal and metalloid concentrations in association with birth outcomes in Northern Puerto Rico by Ashrap, Pahriya, Watkins, Deborah J., Mukherjee, Bhramar, Boss, Jonathan, Richards, Michael J., Rosario, Zaira, Vélez-Vega, Carmen M., Alshawabkeh, Akram, Cordero, José F., Meeker, John D.

“…•First study to assess maternal metals in relation to birth outcomes in Puerto Rico.•Highlights the importance of assessing the effects of mixtures on health…”
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