Search Results - "MUIR, Amanda"

Tolerance to Dietary Antigens in the Upper Intestine Through Chopping of Gasdermin D by Muir, Amanda B

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EoE disease monitoring: Where we are and where we are going by Godwin, Bridget, Wilkins, Benjamin, Muir, Amanda B

“…To review literature on various methods of monitoring and characterizing eosinophilic esophagitis (EoE) with respect to their validity as well as risk to the…”
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Epithelial-stromal crosstalk and fibrosis in eosinophilic esophagitis by Muir, Amanda B., Wang, Joshua X., Nakagawa, Hiroshi

“…Eosinophilic esophagitis (EoE) is a food allergen-induced inflammatory disorder. EoE is increasingly recognized as a cause of swallowing dysfunction, food…”
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Increasing Rates of Diagnosis, Substantial Co-Occurrence, and Variable Treatment Patterns of Eosinophilic Gastritis, Gastroenteritis, and Colitis Based on 10-Year Data Across a Multicenter Consortium by Pesek, Robert D, Reed, Craig C, Muir, Amanda B, Fulkerson, Patricia C, Menard-Katcher, Calies, Falk, Gary W, Kuhl, Jonathan, Martin, Ellen K, Magier, Adam Z, Ahmed, Faria, Demarshall, Maureen, Gupta, Ankur, Gross, Jonathan, Ashorobi, Tokunbo, Carpenter, Christina L, Krischer, Jeffrey P, Gonsalves, Nirmala, Spergel, Jonathan M, Gupta, Sandeep K, Furuta, Glenn T, Rothenberg, Marc E, Dellon, Evan S

“…The literature related to eosinophilic gastritis (EG), gastroenteritis (EGE), and colitis (EC) is limited. We aimed to characterize rates of diagnosis,…”
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It takes a village to manage eosinophilic esophagitis by Muir, Amanda B., Brown-Whitehorn, Terri, Cianferoni, Antonella

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Comorbid Diagnosis of Eosinophilic Esophagitis and Inflammatory Bowel Disease in the Pediatric Population by Moore, Hillary, Wechsler, Joshua, Frost, Carrie, Whiteside, Elizabeth, Baldassano, Robert, Markowitz, Jonathan, Muir, Amanda B.

“…ABSTRACT Background and Aims: The incidence and prevalence of eosinophilic esophagitis (EoE) and inflammatory bowel disease (IBD) are rising with similar…”
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Embracing Diversity, Equity, Inclusion, and Accessibility in Eosinophilic Gastrointestinal Diseases by Muir, Amanda B., Bailey, Dominique D., Mehta, Pooja

“…Eosinophilic gastrointestinal diseases (EGIDs) including eosinophilic esophagitis (EoE) are rare diseases in which eosinophils abnormally infiltrate the…”
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KLF4 activates NFκB signaling and esophageal epithelial inflammation via the Rho-related GTP-binding protein RHOF by Shaverdashvili, Khvaramze, Padlo, Jennie, Weinblatt, Daniel, Jia, Yang, Jiang, Wenpeng, Rao, Divya, Laczkó, Dorottya, Whelan, Kelly A, Lynch, John P, Muir, Amanda B, Katz, Jonathan P

“…Understanding the regulatory mechanisms within esophageal epithelia is essential to gain insight into the pathogenesis of esophageal diseases, which are among…”
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Thymic stromal lymphopoietin–elicited basophil responses promote eosinophilic esophagitis by Noti, Mario, Wojno, Elia D Tait, Kim, Brian S, Siracusa, Mark C, Giacomin, Paul R, Nair, Meera G, Benitez, Alain J, Ruymann, Kathryn R, Muir, Amanda B, Hill, David A, Chikwava, Kudakwashe R, Moghaddam, Amin E, Sattentau, Quentin J, Alex, Aneesh, Zhou, Chao, Yearley, Jennifer H, Menard-Katcher, Paul, Kubo, Masato, Obata-Ninomiya, Kazushige, Karasuyama, Hajime, Comeau, Michael R, Brown-Whitehorn, Terri, de Waal Malefyt, Rene, Sleiman, Patrick M, Hakonarson, Hakon, Cianferoni, Antonella, Falk, Gary W, Wang, Mei-Lun, Spergel, Jonathan M, Artis, David

“…Eosinophilic esophagitis (EoE) is characterized by esophageal eosinophilia, but the underlying mechanisms promoting eosinophil accumulation remain unclear…”
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Persistent esophageal changes after histologic remission in eosinophilic esophagitis by Ruffner, Melanie A., Shoda, Tetsuo, Lal, Megha, Mrozek, Zoe, Muir, Amanda B., Spergel, Jonathan M., Dellon, Evan S., Rothenberg, Marc E.

“…[Display omitted] Eosinophilic esophagitis (EoE) is characterized by persistent or relapsing allergic inflammation, and both clinical and histologic features…”
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Pathophysiology of Eosinophilic Esophagitis by Kennedy, Kanak V., Muir, Amanda B., Ruffner, Melanie A.

“…Eosinophilic esophagitis (EoE) is a chronic, progressive immune-mediated disease associated with antigen-driven type 2 inflammation and symptoms of esophageal…”
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Medical Management of Eosinophilic Esophagitis in Pediatric Patients by Ruffner, Melanie A., Juste, Linola, Muir, Amanda B.

“…Eosinophilic esophagitis is an immune-mediated allergic disease of the esophagus that affects pediatric patients of all ages. The diagnosis is made by…”
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Influence of Age and Eosinophilic Esophagitis on Esophageal Distensibility in a Pediatric Cohort by Menard-Katcher, Calies, Benitez, Alain J, Pan, Zhaoxing, Ahmed, Faria N, Wilkins, Benjamin J, Capocelli, Kelley E, Liacouras, Chris A, Verma, Ritu, Spergel, Jonathan M, Furuta, Glenn T, Muir, Amanda B

“…Sequelae of eosinophilic esophagitis (EoE) include food impaction and esophageal stricture. Duration of inflammation is a predicted risk factor; however,…”
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Preferential Secretion of Thymic Stromal Lymphopoietin (TSLP) by Terminally Differentiated Esophageal Epithelial Cells: Relevance to Eosinophilic Esophagitis (EoE) by Chandramouleeswaran, Prasanna M, Shen, Dawen, Lee, Anna J, Benitez, Alain, Dods, Kara, Gambanga, Fiona, Wilkins, Benjamin J, Merves, Jamie, Noah, Yuliana, Toltzis, Sarit, Yearley, Jennifer H, Spergel, Jonathan M, Nakagawa, Hiroshi, Malefyt, Rene deWaal, Muir, Amanda B, Wang, Mei-Lun

“…Eosinophilic esophagitis (EoE) is a chronic Th2 and food antigen-mediated disease characterized by esophageal eosinophilic infiltration. Thymic stromal…”
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Treatment goals in eosinophilic esophagitis: Looking beyond eosinophil count by Kennedy, Kanak V., Umeweni, Chizoba N., Ruffner, Melanie, Muir, Amanda B.

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Single cell transcriptomic analysis reveals cellular diversity of murine esophageal epithelium by Kabir, Mohammad Faujul, Karami, Adam L., Cruz-Acuña, Ricardo, Klochkova, Alena, Saxena, Reshu, Mu, Anbin, Murray, Mary Grace, Cruz, Jasmine, Fuller, Annie D., Clevenger, Margarette H., Chitrala, Kumaraswamy Naidu, Tan, Yinfei, Keith, Kelsey, Madzo, Jozef, Huang, Hugh, Jelinek, Jaroslav, Karakasheva, Tatiana, Hamilton, Kathryn E., Muir, Amanda B., Tétreault, Marie-Pier, Whelan, Kelly A.

“…Although morphologic progression coupled with expression of specific molecular markers has been characterized along the esophageal squamous differentiation…”
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Proton pump inhibitors and esophageal atresia: Too early to change clinical practice by Manfredi, Michael D, Yasuda, Jessica, Mahon, Mark, Kennedy, Kanak V, Menard-Katcher, Caliesz, Mitchel, Elana, Muir, Amanda B

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Improvement in eosinophilic esophagitis when using dupilumab for other indications or compassionate use by Spergel, Benjamin L., Ruffner, Melanie A., Godwin, Bridget C., Liacouras, Chris A., Cianferoni, Antonella, Gober, Laura, Hill, David A., Brown-Whitehorn, Terri F., Chaiboonma, Kira, Aceves, Seema A., Muir, Amanda M., Spergel, Jonathan M.

“…Dupilumab has been approved to treat atopic dermatitis, asthma, and nasal polyps and is in active clinical trials for the treatment of eosinophilic esophagitis…”
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Patient-derived organoids as a platform for modeling a patient’s response to chemoradiotherapy in esophageal cancer by Karakasheva, Tatiana A., Gabre, Joel T., Sachdeva, Uma M., Cruz-Acuña, Ricardo, Lin, Eric W., DeMarshall, Maureen, Falk, Gary W., Ginsberg, Gregory G., Yang, Zhaohai, Kim, Michele M., Diffenderfer, Eric S., Pitarresi, Jason R., Li, Jinyang, Muir, Amanda B., Hamilton, Kathryn E., Nakagawa, Hiroshi, Bass, Adam J., Rustgi, Anil K.

“…3D patient-derived organoids (PDOs) have been utilized to evaluate potential therapies for patients with different cancers. However, the use of PDOs created…”
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Persistent Basal Cell Hyperplasia is Associated with Clinical and Endoscopic Findings in Patients With Histologically Inactive Eosinophilic Esophagitis by Whelan, Kelly A, Godwin, Bridget C, Wilkins, Benjamin, Elci, Okan U, Benitez, Alain, DeMarshall, Maureen, Sharma, Medha, Gross, Jonathan, Klein-Szanto, Andres J, Liacouras, Chris A, Dellon, Evan S, Spergel, Jonathan M, Falk, Gary W, Muir, Amanda B, Nakagawa, Hiroshi

“…AbstractBackground & AimsAlthough eosinophil count is the standard used to monitor disease activity in patients with eosinophilic esophagitis (EoE), there are…”
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