Search Results - "MOUSTAPHA HASSAN"
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SERS Quantification and Characterization of Proteins and Other Biomolecules
Published in Langmuir (26-09-2017)“…Changes in protein expression levels and protein structure may indicate genomic mutations and may be related to some diseases. Therefore, the precise…”
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2
Inhibition of proteasome deubiquitinating activity as a new cancer therapy
Published in Nature medicine (01-12-2011)“…b-AP15 is a novel inhibitor of proteasome activity, with a different mechanism of action than the available and widely used proteasome inhibitors such as…”
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3
Autophagy orchestrates resistance in hepatocellular carcinoma cells
Published in Biomedicine & pharmacotherapy (01-05-2023)“…Treatment resistance is one of the major barriers for therapeutic strategies in hepatocellular carcinoma (HCC). Many studies have indicated that chemotherapy…”
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4
Hematologic malignancies in elderly patients
Published in Haematologica (Roma) (01-07-2014)Get full text
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P53/NANOG balance; the leading switch between poorly to well differentiated status in liver cancer cells
Published in Frontiers in oncology (2024)“…Enforcing a well-differentiated state on cells requires tumor suppressor p53 activation as a key player in apoptosis induction and well differentiation. In…”
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Umbilical Cord Blood-Derived Monocytes as A Reliable Source of Functional Macrophages for Biomedical Research
Published in Cell journal (Yakhteh) (01-08-2023)“…Objective: Macrophages are multifunctional immune cells widely used in immunological research. While autologous macrophages have been widely used in several…”
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7
Cytochrome P450 Oxidoreductase Influences CYP2B6 Activity in Cyclophosphamide Bioactivation
Published in PloS one (06-11-2015)“…Cyclophosphamide is commonly used as an important component in conditioning prior to hematopoietic stem cell transplantation, a curative treatment for several…”
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8
Mini review ATF4 and GRP78 as novel molecular targets in ER-Stress modulation for critical COVID-19 patients
Published in Molecular biology reports (01-02-2022)“…Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has resulted in more than 4.4 million deaths…”
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Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1 , PRDM16 or SETBP1
Published in Nature medicine (01-04-2006)“…Gene transfer into hematopoietic stem cells has been used successfully for correcting lymphoid but not myeloid immunodeficiencies. Here we report on two adults…”
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10
Tuned activation of MSLN-CAR T cells induces superior antitumor responses in ovarian cancer models
Published in Journal for immunotherapy of cancer (01-02-2023)“…BackgroundLimited persistence of functional CAR T cells in the immunosuppressive solid tumor microenvironment remains a major hurdle in the successful…”
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11
Flavin-containing monooxygenase 3 (FMO3) role in busulphan metabolic pathway
Published in PloS one (09-11-2017)“…Busulphan (Bu) is an alkylating agent used in the conditioning regimen prior to hematopoietic stem cell transplantation (HSCT). Bu is extensively metabolized…”
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12
CT Scanning and MATLAB Calculations for Preservation of Coptic Mural Paintings in Historic Egyptian Monasteries
Published in Scientific reports (07-03-2019)“…Investigations of Coptic mural paintings in historic churches and monasteries demand a deep understanding of the micro structure of the mural painting layers…”
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13
Importance of the surface chemistry of nanoparticles on peroxidase-like activity
Published in Biochemical and biophysical research communications (09-09-2017)“…We report the studies on origin of peroxidase-like activity for gold nanoparticles, as well as the impact from morphology and surface charge of nanoparticles…”
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14
A general covalent binding model between cytotoxic selenocompounds and albumin revealed by mass spectrometry and X-ray absorption spectroscopy
Published in Scientific reports (27-01-2020)“…Selenocompounds (SeCs) are promising therapeutic agents for a wide range of diseases including cancer. The treatment results are heterogeneous and dependent on…”
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15
Application of Stem Cell-Derived Extracellular Vesicles as an Innovative Theranostics in Microbial Diseases
Published in Frontiers in microbiology (30-11-2021)“…Extracellular vesicles (EVs), as nano-/micro-scale vehicles, are membranous particles containing various cargoes including peptides, proteins, different types…”
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16
Role of pharmacogenetics in busulfan/cyclophosphamide conditioning therapy prior to hematopoietic stem cell transplantation
Published in Pharmacogenomics (01-01-2013)“…Hematopoietic stem cell transplantation (HSCT) is a curative treatment for several malignant and nonmalignant disorders. Busulfan (Bu) and cyclophosphamide…”
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17
Transplanted Bone Marrow-Derived Cells Contribute to Human Adipogenesis
Published in Cell metabolism (01-09-2015)“…Because human white adipocytes display a high turnover throughout adulthood, a continuous supply of precursor cells is required to maintain adipogenesis. Bone…”
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18
Endoplasmic reticulum stress inhibits AR expression via the PERK/eIF2α/ATF4 pathway in luminal androgen receptor triple-negative breast cancer and prostate cancer
Published in NPJ breast cancer (10-01-2022)“…Androgen receptor (AR) is an important prognostic marker and therapeutic target in luminal androgen receptor triple-negative breast cancer (LAR TNBC) and…”
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19
Platelet-Rich Plasma in Regenerative Medicine: Possible Applications in Management of Burns and Post-Burn Scars: A Review
Published in Cell journal (Yakhteh) (01-05-2023)“…Contribution of platelets in tissue regeneration and their possible application in regenerative medicine, which is primarily mediated via secretion of granular…”
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20
Application of XBP1s Decoy Oligodeoxynucleotide Attenuates Cancerous Phenotype in Huh-7 Hepatocellular Carcinoma Cells
Published in Cell journal (Yakhteh) (2024)“…The spliced form of X-box binding protein 1 (XBP1s) is a key transcription factor in the unfolded protein response (UPR), an adaptive mechanism for cell…”
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