Search Results - "MOURELATOS, Z"

SMN interacts with a novel family of hnRNP and spliceosomal proteins by Mourelatos, Zissimos, Abel, Linda, Yong, Jeongsik, Kataoka, Naoyuki, Dreyfuss, Gideon

“…Spinal muscular atrophy (SMA) is a common neurodegenerative disease caused by deletion or loss‐of‐function mutations of the survival of motor neurons (SMN)…”
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AN EFFICIENT CRANKSHAFT DYNAMIC ANALYSIS USING SUBSTRUCTURING WITH RITZ VECTORS by MOURELATOS, Z.P.

“…A structural analysis using dynamic substructuring with Ritz vectors is presented for predicting the dynamic response of an engine crankshaft, based on the…”
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Computational analysis for dynamic response of a rotating shaft on flexible support structure with clearances by Hu, K., Mourelatos, Z.P., Vlahopoulos, N.

“…A finite element-based formulation for modelling the dynamic behavior of a rotating flexible shaft supported by a flexible support structure is presented. The…”
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A FINITE ELEMENT FORMULATION FOR COUPLING RIGID AND FLEXIBLE BODY DYNAMICS OF ROTATING BEAMS by HU, K., VLAHOPOULOS, N., MOURELATOS, Z.P.

“…The work presented in this paper is based on an existing comprehensive formulation for rotating flexible systems. In the existing formulation the flexible…”
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The Golgi Apparatus of Spinal Cord Motor Neurons in Transgenic Mice Expressing Mutant Cu,Zn Superoxide Dismutase Becomes Fragmented in Early, Preclinical Stages of the Disease by Mourelatos, Zissimos, Gonatas, Nicholas K., Stieber, Anna, Gurney, Mark E., Mauro C. Dal Canto

“…Dominant mutations of the SOD1 gene encoding Cu,Zn superoxide dismutase have been found in members of certain families with familial amyotrophic lateral…”
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A crankshaft system model for structural dynamic analysis of internal combustion engines by Mourelatos, Zissimos P.

“…A system model for analyzing the dynamic behavior of an internal combustion engine crankshaft is described. The model couples the crankshaft structural…”
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In Alzheimer's disease the Golgi apparatus of a population of neurons without neurofibrillary tangles is fragmented and atrophic by Stieber, A, Mourelatos, Z, Gonatas, NK

“…Recent immunocytochemical and morphometric studies in amyotrophic lateral sclerosis, Alzheimer's disease (AD), and aging indicate that the neuronal Golgi…”
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Reliability-based evaluation of automotive wind noise quality by Zou, T., Mahadevan, S., Mourelatos, Z.P.

“…This paper proposes an efficient method for the reliability analysis of a vehicle body–door subsystem with respect to an important quality issue—wind noise. A…”
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A human, ATP-independent, RISC assembly machine fueled by pre-miRNA by Maniataki, Elisavet, Mourelatos, Zissimos

“…RNA interference (RNAi) is mediated by RNA-induced silencing complexes (RISCs), which are guided by microRNAs (miRNAs) or short interfering RNAs (siRNAs) to…”
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FUS regulates genes coding for RNA-binding proteins in neurons by binding to their highly conserved introns by Nakaya, Tadashi, Alexiou, Panagiotis, Maragkakis, Manolis, Chang, Alexandra, Mourelatos, Zissimos

“…Dominant mutations and mislocalization or aggregation of Fused in Sarcoma (FUS), an RNA-binding protein (RBP), cause neuronal degeneration in Amyotrophic…”
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Calculation of Journal Bearing Dynamic Characteristics Including Journal Misalignment and Bearing Structural Deformation by EBRAT, OMIDREZA, MOURELATOS, ZISSIMOS P., VLAHOPOULOS, NICKOLAS, VAIDYANATHAN, KUMAR

“…A detailed journal bearing analysis for accurate evaluation of film dynamic characteristics is presented. The new formulation is based on a local perturbation…”
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Fragmentation of the Golgi apparatus of motor neurons in amyotrophic lateral sclerosis by Gonatas, NK, Stieber, A, Mourelatos, Z, Chen, Y, Gonatas, JO, Appel, SH, Hays, AP, Hickey, WF, Hauw, JJ

“…The Golgi apparatus (complex) is at the center stage of important functions of processing and transport of plasma membrane, lysosomal, and secreted proteins…”
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yeast functional screen predicts new candidate ALS disease genes by Couthouis, Julien, Hart, Michael P, Shorter, James, DeJesus-Hernandez, Mariely, Erion, Renske, Oristano, Rachel, Liu, Annie X, Ramos, Daniel, Jethava, Niti, Hosangadi, Divya, Epstein, James, Chiang, Ashley, Diaz, Zamia, Nakaya, Tadashi, Ibrahim, Fadia, Kim, Hyung-Jun, Solski, Jennifer A, Williams, Kelly L, Mojsilovic-Petrovic, Jelena, Ingre, Caroline, Boylan, Kevin, Graff-Radford, Neill R, Dickson, Dennis W, Clay-Falcone, Dana, Elman, Lauren, McCluskey, Leo, Greene, Robert, Kalb, Robert G, Lee, Virginia M.-Y, Trojanowski, John Q, Ludolph, Albert, Robberecht, Wim, Andersen, Peter M, Nicholson, Garth A, Blair, Ian P, King, Oliver D, Bonini, Nancy M, Van Deerlin, Vivianna, Rademakers, Rosa, Mourelatos, Zissimos, Gitler, Aaron D

“…Amyotrophic lateral sclerosis (ALS) is a devastating and universally fatal neurodegenerative disease. Mutations in two related RNA-binding proteins, TDP-43 and…”
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Neuro-ophthalmologic manifestations of a paraneoplastic syndrome and testicular carcinoma by BENNETT, J. L, GALETTA, S. L, FROHMAN, L. P, MOURELATOS, Z, GULTEKIN, S. H, DALMAU, J. O, POSNER, J. B

“…The authors report two patients with testicular cancer who exhibited supranuclear gaze disorders as a manifestation of a paraneoplastic brainstem…”
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The microRNA world: small is mighty by Nelson, Peter, Kiriakidou, Marianthi, Sharma, Anup, Maniataki, Elsa, Mourelatos, Zissimos

“…A new paradigm of RNA-directed gene expression regulation has emerged recently, profound in scope but arresting in the apparent simplicity of its core…”
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A combined computational-experimental approach predicts human microRNA targets by Kiriakidou, Marianthi, Nelson, Peter T, Kouranov, Andrei, Fitziev, Petko, Bouyioukos, Costas, Mourelatos, Zissimos, Hatzigeorgiou, Artemis

“…A new paradigm of gene expression regulation has emerged recently with the discovery of microRNAs (miRNAs). Most, if not all, miRNAs are thought to control…”
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Fragmentation of the Golgi apparatus of motor neurons in amyotrophic lateral sclerosis (ALS). Clinical studies in ALS of Guam and experimental studies in deafferented neurons and in beta,beta'- iminodipropionitrile axonopathy by Mourelatos, Z, Hirano, A, Rosenquist, AC, Gonatas, NK

“…Previous morphological immunoenzymatic studies with organelle-specific antibodies have disclosed an apparent fragmentation of the Golgi apparatus in large…”
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Microarray-based, high-throughput gene expression profiling of microRNAs by Mourelatos, Zissimos, Nelson, Peter T, Baldwin, Don A, Scearce, L Marie, Oberholtzer, J Carl, Tobias, John W

“…MicroRNAs (miRNAs) are small regulatory RNAs that serve fundamental biological roles across eukaryotic species. We describe a new method for high-throughput…”
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Mitochondrial protein BmPAPI modulates the length of mature piRNAs by Honda, Shozo, Kirino, Yoriko, Maragkakis, Manolis, Alexiou, Panagiotis, Ohtaki, Akashi, Murali, Ramachandran, Mourelatos, Zissimos, Kirino, Yohei

“…PIWI proteins and their associated PIWI-interacting RNAs (piRNAs) protect genome integrity by silencing transposons in animal germlines. The molecular…”
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