Search Results - "MOUNIER, Catherine"
-
1
Monounsaturated Fatty Acids in Obesity-Related Inflammation
Published in International journal of molecular sciences (30-12-2020)“…Obesity is an important aspect of the metabolic syndrome and is often associated with chronic inflammation. In this context, inflammation of organs…”
Get full text
Journal Article -
2
Hormonal and nutritional regulation of SCD1 gene expression
Published in Biochimie (2011)“…Stearoyl-CoA Desaturase 1 (SCD1) is the rate limiting enzyme catalyzing the biosynthesis of monounsaturated fatty acids preferentially from palmitoyl-CoA and…”
Get full text
Journal Article -
3
Oleate Promotes Triple-Negative Breast Cancer Cell Migration by Enhancing Filopodia Formation through a PLD/Cdc42-Dependent Pathway
Published in International journal of molecular sciences (01-04-2024)“…Breast cancer, particularly triple-negative breast cancer (TNBC), poses a global health challenge. Emerging evidence has established a positive association…”
Get full text
Journal Article -
4
Unveiling the MUFA-Cancer Connection: Insights from Endogenous and Exogenous Perspectives
Published in International journal of molecular sciences (01-06-2023)“…Monounsaturated fatty acids (MUFAs) have been the subject of extensive research in the field of cancer due to their potential role in its prevention and…”
Get full text
Journal Article -
5
Exploring the impacts of ketogenic diet on reversible hepatic steatosis: initial analysis in male mice
Published in Frontiers in nutrition (Lausanne) (21-03-2024)“…Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most common chronic liver disease. Ketogenic diet (KD), a diet with very low intake in…”
Get full text
Journal Article -
6
Gut Microbiota and Metabolic Health: The Potential Beneficial Effects of a Medium Chain Triglyceride Diet in Obese Individuals
Published in Nutrients (12-05-2016)“…Obesity and associated metabolic complications, such as non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D), are in constant increase around…”
Get full text
Journal Article Book Review -
7
Oleate activates SREBP-1 signaling activity in SCD1 -deficient hepatocytes
Published in American journal of physiology: endocrinology and metabolism (01-12-2017)“…Stearoyl-CoA desaturase-1 (SCD1) is a key player in lipid metabolism. SCD1 catalyzes the synthesis of monounsaturated fatty acids (MUFA). MUFA are then…”
Get more information
Journal Article -
8
Stearoyl-CoA Desaturase inhibition reverses immune, synaptic and cognitive impairments in an Alzheimer’s disease mouse model
Published in Nature communications (20-04-2022)“…The defining features of Alzheimer’s disease (AD) include alterations in protein aggregation, immunity, lipid metabolism, synapses, and learning and memory. Of…”
Get full text
Journal Article -
9
Apolipoprotein D overexpression alters hepatic prostaglandin and omega fatty acid metabolism during the development of a non-inflammatory hepatic steatosis
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-04-2019)“…Apolipoprotein D (ApoD) is a secreted lipocalin associated with neuroprotection and lipid metabolism. Overexpression of ApoD in mouse neural tissue induces the…”
Get full text
Journal Article -
10
SCD1 activity promotes cell migration via a PLD-mTOR pathway in the MDA-MB-231 triple-negative breast cancer cell line
Published in Breast cancer (Tokyo, Japan) (01-07-2020)“…Background Breast cancer is the most common cancer in women. Despite high survival rates in Western countries, treatments are less effective in metastatic…”
Get full text
Journal Article -
11
Apolipoprotein D in Oxidative Stress and Inflammation
Published in Antioxidants (28-04-2023)“…Apolipoprotein D (ApoD) is lipocalin able to bind hydrophobic ligands. The APOD gene is upregulated in a number of pathologies, including Alzheimer's disease,…”
Get full text
Journal Article -
12
-
13
Decreasing stearoyl‐CoA desaturase‐1 expression inhibits β‐catenin signaling in breast cancer cells
Published in Cancer science (01-01-2013)“…Stearoyl‐CoA desaturase‐1 (SCD1) is an endoplasmic reticulum anchored enzyme catalyzing the synthesis of monounsaturated fatty acids, mainly palmytoleyl‐CoA…”
Get full text
Journal Article -
14
Hexanoic, Octanoic and Decanoic Acids Promote Basal and Insulin-Induced Phosphorylation of the Akt-mTOR Axis and a Balanced Lipid Metabolism in the HepG2 Hepatoma Cell Line
Published in Molecules (Basel, Switzerland) (11-09-2018)“…Metabolic illnesses such as non-alcoholic fatty liver disease (NAFLD) are in constant increase worldwide. Highly consumed long chain fatty acids (LCFA) are…”
Get full text
Journal Article -
15
Cerebral Apolipoprotein D Exits the Brain and Accumulates in Peripheral Tissues
Published in International journal of molecular sciences (16-04-2021)“…Apolipoprotein D (ApoD) is a secreted lipocalin associated with neuroprotection and lipid metabolism. In rodent, the bulk of its expression occurs in the…”
Get full text
Journal Article -
16
SCD1 deficiency protects mice against ethanol-induced liver injury
Published in Biochimica et biophysica acta (01-11-2016)“…Stearoyl-CoA desaturase 1 (SCD1) is a delta-9 fatty acid desaturase that catalyzes the synthesis of mono-unsaturated fatty acids (MUFA). SCD1 is a critical…”
Get full text
Journal Article -
17
Apolipoprotein D Transgenic Mice Develop Hepatic Steatosis through Activation of PPARγ and Fatty Acid Uptake
Published in PloS one (17-06-2015)“…Transgenic mice (Tg) overexpressing human apolipoprotein D (H-apoD) in the brain are resistant to neurodegeneration. Despite the use of a neuron-specific…”
Get full text
Journal Article -
18
Key role of the ERK1/2 MAPK pathway in the transcriptional regulation of the Stearoyl-CoA Desaturase (SCD1) gene expression in response to leptin
Published in Molecular and cellular endocrinology (05-05-2010)“…Stearoyl-CoA Desaturase-1 (SCD1) is the rate limiting enzyme catalyzing the synthesis of monounsaturated fatty acids. Variation of SCD1 activity and the ratio…”
Get full text
Journal Article -
19
Surface Response Based Modeling of Liposome Characteristics in a Periodic Disturbance Mixer
Published in Micromachines (Basel) (25-02-2020)“…Liposomes nanoparticles (LNPs) are vesicles that encapsulate drugs, genes, and imaging labels for advanced delivery applications. Control and tuning liposome…”
Get full text
Journal Article -
20
Human apolipoprotein D overexpression in transgenic mice induces insulin resistance and alters lipid metabolism
Published in American journal of physiology: endocrinology and metabolism (01-04-2009)“…Apolipoprotein D (apoD), a widely expressed lipocalin, has the capacity to transport small hydrophobic molecules. Although it has been proposed that apoD may…”
Get more information
Journal Article