Search Results - "MOUILLAC, B."

Oxytocin and Vasopressin Agonists and Antagonists as Research Tools and Potential Therapeutics by Manning, M., Misicka, A., Olma, A., Bankowski, K., Stoev, S., Chini, B., Durroux, T., Mouillac, B., Corbani, M., Guillon, G.

“…We recently reviewed the status of peptide and nonpeptide agonists and antagonists for the V1a, V1b and V2 receptors for arginine vasopressin (AVP) and the…”
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Structural bases of vasopressin/oxytocin receptor function by Barberis, C, Mouillac, B, Durroux, T

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Past, present and future of vasopressin and oxytocin receptor oligomers, prototypical GPCR models to study dimerization processes by Cottet, M, Albizu, L, Perkovska, S, Jean-Alphonse, F, Rahmeh, R, Orcel, H, Méjean, C, Granier, S, Mendre, C, Mouillac, B, Durroux, T

“…The G protein-coupled receptors (GPCRs) play a major role in the regulation of physiological function. The emergence of the concept of GPCR oligomerization…”
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Activity of Mambaquaretin toxin on kidney disease via its interaction with vasopressin V2 receptor by Ciolek, J., Reinfrank, H., Servent, D., Mourier, G., Mouillac, B., Quinton, L., Mendre, C., Witzgall, R., Gilles, N.

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Fluorescent agonists and antagonists for vasopressin/oxytocin G protein-coupled receptors: usefulness in ligand screening assays and receptor studies by Mouillac, B, Manning, M, Durroux, T

“…Different series of fluorescent agonists and antagonists have been developed and characterized for arginine-vasopressin and oxytocin G protein-coupled…”
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Cloning, expression and pharmacological characterization of a vasopressin-related receptor in an annelid, the leech Theromyzon tessulatum by Levoye, A, Mouillac, B, Rivière, G, Vieau, D, Salzet, M, Breton, C

“…In annelids, it has been established that arginine-vasopressin (AVP)/oxytocin (OT) superfamily peptides are involved in the maintenance of water and…”
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The Two NK-1 Binding Sites Correspond to Distinct, Independent, and Non-Interconvertible Receptor Conformational States As Confirmed by Plasmon-Waveguide Resonance Spectroscopy by Alves, Isabel D, Delaroche, Diane, Mouillac, Bernard, Salamon, Zdzislaw, Tollin, Gordon, Hruby, Victor J, Lavielle, Solange, Sagan, Sandrine

“…Two nonstoichiometric ligand binding sites have been previously reported for the NK-1 receptor, with the use of classical methods (radioligand binding and…”
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Agonist-modulated palmitoylation of beta 2-adrenergic receptor in Sf9 cells by Mouillac, B, Caron, M, Bonin, H, Dennis, M, Bouvier, M

“…The palmitoylation of the human beta 2-adrenergic receptor (beta 2-AR) was studied in recombinant baculovirus-infected insect Sf9 cells. At 48 h…”
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Altered phosphorylation and desensitization patterns of a human beta 2‐adrenergic receptor lacking the palmitoylated Cys341 by Moffett, S., Mouillac, B., Bonin, H., Bouvier, M.

“…Exposure of beta 2‐adrenergic receptors to agonists causes a rapid desensitization of the receptor‐stimulated adenylyl cyclase, associated with an increased…”
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Tyr115 is the key residue for determining agonist selectivity in the V1a vasopressin receptor by Chini, B., Mouillac, B., Ala, Y., Balestre, M.N., Trumpp‐Kallmeyer, S., Hoflack, J., Elands, J., Hibert, M., Manning, M., Jard, S.

“…Using a three‐dimensional model of G protein‐coupled receptors (GPCR), we have previously succeeded in docking the neurohypophysial hormone…”
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Tyr115 is the key residue for determining agonist selectivity in the V1a vasopressin receptor by Chini, B., Mouillac, B., Ala, Y., Balestre, M.N., Trumpp-Kallmeyer, S., Hoflack, J., Elands, J., Hibert, M., Manning, M., Jard, S.

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Peptide and non-peptide agonists and antagonists for the vasopressin and oxytocin V1a, V1b, V2 and OT receptors: research tools and potential therapeutic agents by Manning, Maurice, Stoev, Stoytcho, Chini, Bice, Durroux, Thierry, Mouillac, Bernard, Guillon, Gilles

“…Oxytocin (OT) and vasopressin (AVP) mediate their biological actions by acting on four known receptors: The OT (uterine) and the AVP V(1a) (vasopressor), V(1b)…”
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Differential effects of heparin on inositol 1,4,5-trisphosphate binding, metabolism, and calcium release activity in the bovine adrenal cortex by Guillemette, G, Lamontagne, S, Boulay, G, Mouillac, B

“…In a wide variety of cells, inositol-1,4,5-triphosphate is a second messenger that interacts with specific intracellular receptors and triggers the release of…”
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Design, Synthesis and Pharmacological Characterization of a Potent Radioiodinated and Photoactivatable Peptidic Oxytocin Antagonist by Carnazzi, Eric, Aumelas, André, Mouillac, Bernard, Breton, Christophe, Guillou, Laurent, Barberis, Claude, Seyer, René

“…Using a segment strategy, we have synthesized four iodinated photoactivatable cyclic peptidic ligands of oxytocin, bearing a β-mercapto-ββ-cyclopentamethylene…”
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Structure of the vasopressin hormone-V2 receptor-β-arrestin1 ternary complex by Bous, Julien, Fouillen, Aurélien, Orcel, Hélène, Trapani, Stefano, Cong, Xiaojing, Fontanel, Simon, Saint-Paul, Julie, Lai-Kee-Him, Joséphine, Urbach, Serge, Sibille, Nathalie, Sounier, Rémy, Granier, Sébastien, Mouillac, Bernard, Bron, Patrick

“…Arrestins interact with G protein-coupled receptors (GPCRs) to stop G protein activation and to initiate key signaling pathways. Recent structural studies shed…”
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Genomic and non-genomic mechanisms of oxytocin receptor regulation by Zingg, H H, Grazzini, E, Breton, C, Larcher, A, Rozen, F, Russo, C, Guillon, G, Mouillac, B

“…Our recent studies have shown that regulation of uterine oxytocin (OT) binding involves at least two different mechanism: Estradiol (E2)-induced upregulation…”
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Palmitoylation of G-protein-coupled receptors: a dynamic modification with functional consequences by Bouvier, M, Moffett, S, Loisel, T P, Mouillac, B, Hebert, T, Chidiac, P

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Bringing GPCR Structural Biology to Medical Applications: Insights from Both V2 Vasopressin and Mu-Opioid Receptors by Fouillen, Aurélien, Bous, Julien, Granier, Sébastien, Mouillac, Bernard, Sounier, Remy

“…G-protein coupled receptors (GPCRs) are versatile signaling proteins that regulate key physiological processes in response to a wide variety of extracellular…”
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Functional Architecture of Vasopressin/Oxytocin Receptors by Hibert, M., Hoflack, J., Trumpp-Kallmeyer, S., Mouillac, B., Chini, B., Mahea, E., Cotte, N., Jard, S., Manning, M., Barberis, C.

“…Abstract Three-dimensional models of G protein-coupled receptors (GPCR) have been defined using most experimental data available and protein modeling…”
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Oxytocin and Vasopressin V1a and V2 Receptors Form Constitutive Homo- and Heterodimers during Biosynthesis by Terrillon, Sonia, Durroux, Thierry, Mouillac, Bernard, Breit, Andreas, Ayoub, Mohammed A, Taulan, Magali, Jockers, Ralf, Barberis, Claude, Bouvier, Michel

“…G protein-coupled receptor (GPCR) oligomerization is a growing concept that has emerged from several studies suggesting that GPCRs can form both homo- and…”
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