Search Results - "MOUDGIL, Rohit"

Mechanisms of cardiotoxicity of cancer chemotherapeutic agents: Cardiomyopathy and beyond by Moudgil, Rohit, MD, PhD, Yeh, Edward T.H., MD

“…Abstract Tremendous strides have been made in the treatment of various oncological diseases such that patients are surviving longer and are having better…”
Get full text

Cardiac risk stratification in cancer patients: A longitudinal patient-patient network analysis by Hou, Yuan, Zhou, Yadi, Hussain, Muzna, Budd, G Thomas, Tang, Wai Hong Wilson, Abraham, James, Xu, Bo, Shah, Chirag, Moudgil, Rohit, Popovic, Zoran, Watson, Chris, Cho, Leslie, Chung, Mina, Kanj, Mohamed, Kapadia, Samir, Griffin, Brian, Svensson, Lars, Collier, Patrick, Cheng, Feixiong

“…Cardiovascular disease is a leading cause of death in general population and the second leading cause of mortality and morbidity in cancer survivors after…”
Get full text

Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility by NAGENDRAN, Jayan, ARCHER, Stephen L, LIGHT, Peter E, DYCK, Jason R. B, MICHELAKIS, Evangelos D, SOLIMAN, Daniel, GURTU, Vikram, MOUDGIL, Rohit, HAROMY, Alois, AUBIN, Chantal St, WEBSTER, Linda, REBEYKA, Ivan M, ROSS, David B

“…Sildenafil was recently approved for the treatment of pulmonary arterial hypertension. The beneficial effects of phosphodiesterase type 5 (PDE5) inhibitors in…”
Get full text

Hypoxic pulmonary vasoconstriction by Moudgil, Rohit, Michelakis, Evangelos D, Archer, Stephen L

“…Department of Medicine (Cardiology) and the Vascular Biology Group, University of Alberta, Alberta, Canada Humans encounter hypoxia throughout their lives…”
Get full text

Machine Learning-Based Risk Assessment for Cancer Therapy-Related Cardiac Dysfunction in 4300 Longitudinal Oncology Patients by Zhou, Yadi, Hou, Yuan, Hussain, Muzna, Brown, Sherry-Ann, Budd, Thomas, Tang, W H Wilson, Abraham, Jame, Xu, Bo, Shah, Chirag, Moudgil, Rohit, Popovic, Zoran, Cho, Leslie, Kanj, Mohamed, Watson, Chris, Griffin, Brian, Chung, Mina K, Kapadia, Samir, Svensson, Lars, Collier, Patrick, Cheng, Feixiong

“…Background The growing awareness of cardiovascular toxicity from cancer therapies has led to the emerging field of cardio-oncology, which centers on…”
Get full text

Immune checkpoint inhibitor induced myocarditis, myasthenia gravis, and myositis: A single‐center case series by Longinow, Joshua, Zmaili, Mohammad, Skoza, Warren, Kondoleon, Nicholas, Marquardt, Robert, Calabrese, Cassandra, Funchain, Pauline, Moudgil, Rohit

“…Background Immune checkpoint inhibitors can result in overlap syndrome comprised of myasthenia gravis, myositis and myocarditis. However, the mortality…”
Get full text

Ambient Air Pollution Exposure and Adverse Outcomes Among Medicare Beneficiaries With Heart Failure by Mentias, Amgad, Desai, Milind Y, Pandey, Ambarish, Motairek, Issam, Moudgil, Rohit, Albert, Chonyang, Deo, Salil V, Brook, Robert D, Menon, Venu, Rajagopalan, Sanjay, Al-Kindi, Sadeer

“…Exposure to fine particulate matter (<2.5 um, particulate matter with an aerodynamic diameter <2.5 microns [PM ]) has been implicated in atherogenesis. Limited…”
Get full text

Progressive and Reversible Conduction Disease with Checkpoint Inhibitors by Reddy, Neeti, MD, Moudgil, Rohit, MD PhD, Lopez-Mattei, Juan C., MD, Karimzad, Kaveh, MD, Mouhayar, Elie N., MD, Somaiah, Neeta, MD, Conley, Anthony P., MD, Patel, Shreyaskumar R., MD, Giza, Dana E., MD, Iliescu, Cezar, MD

“…Abstract Novel anti-neoplastic therapies are focused on harnessing our own immune system to fight cancer. To that end, cytotoxic T-lymphocyte-associated…”
Get full text

Immune Checkpoint Inhibitors Mediated Lymphocytic and Giant Cell Myocarditis: Uncovering Etiological Mechanisms by Rikhi, Rishi, Karnuta, Jaret, Hussain, Muzna, Collier, Patrick, Funchain, Pauline, Tang, Wai Hong Wilson, Chan, Timothy A., Moudgil, Rohit

“…The advent of immune checkpoint inhibitors (ICIs) has revolutionized the field of oncology, but these are associated with immune related adverse events. One…”
Get full text

Better prediction of stroke in atrial fibrillation with incorporation of cancer in CHA2DS2VASC score: CCHA2DS2VASC score by Bungo, Brandon, Chaudhury, Pulkit, Arustamyan, Michael, Rikhi, Rishi, Hussain, Muzna, Collier, Patrick, Kanj, Mohamed, Khorana, Alok A., Mentias, Amgad, Moudgil, Rohit

“…Atrial fibrillation (AF) is associated with an increased risk of stroke. Despite evidence linking cancer and thrombosis, cancer is not part of the CHA2DS2VASc…”
Get full text

The Role of K+ Channels in Determining Pulmonary Vascular Tone, Oxygen Sensing, Cell Proliferation, and Apoptosis: Implications in Hypoxic Pulmonary Vasoconstriction and Pulmonary Arterial Hypertension by MOUDGIL, ROHIT, MICHELAKIS, EVANGELOS D., ARCHER, STEPHEN L.

“…Potassium channels are tetrameric, membrane-spanning proteins that selectively conduct K+ at near diffusion-limited rates. Their remarkable ionic selectivity…”
Get full text

Cardio oncology: Digital innovations, precision medicine and health equity by Sadler, Diego, Okwuosa, Tochukwu, Teske, A. J., Guha, Avirup, Collier, Patrick, Moudgil, Rohit, Sarkar, Abdullah, Brown, Sherry-Ann

“…The rapid emergence of cardio-oncology has resulted in a rapid growth of cardio-oncology programs, dedicated professional societies sections and committees,…”
Get full text

Use of computed tomography coronary calcium score for prediction of cardiovascular events in cancer patients: a retrospective cohort analysis by Patel, Sinal, Franco, Francisco X, McDonald, Malcolm, Rivera, Carlos, Perez-Villa, Bernardo, Collier, Patrick, Moudgil, Rohit, Gupta, Neha, Sadler, Diego B

“…CT- coronary calcium score, is one of the most studied and widely available modalities in cardiovascular medicine. Coronary artery calcium score (CACS) is an…”
Get full text

Leveraging innovation, education, and technology for prevention and health equity: Proceedings from the cardiology oncology innovation ThinkTank 2021 by Brown, Sherry-Ann, Berman, Generika, Logan, Jim, Sadler, Diego, Moudgil, Rohit, Patel, Brijesh, Scherrer-Crosbie, Marielle, Addison, Daniel, Cheng, Richard K, Teske, Arco J

Get full text

Regenerative Cell Imaging in Cardiac Repair by Moudgil, Rohit, MD, PhD, Dick, Alexander J., MD

“…Abstract Heart disease continues to be a leading cause of death in the Western world. Although strides have been made in prevention and management of coronary…”
Get full text

Superiority of Ticagrelor Over Clopidogrel in Patients After Cardiac Arrest Undergoing Therapeutic Hypothermia by Moudgil, Rohit, MD, PhD, Al-Turbak, Haytham, MD, Osborne, Christina, BSc, Hibbert, Benjamin, MD, PhD, So, Derek Y.F., MD, Le May, Michel R., MD

“…Abstract Current guidelines suggest that patients undergoing percutaneous coronary intervention (PCI) receive dual-antiplatelet therapy. There are limited data…”
Get full text

Perspectives on the COVID-19 pandemic impact on cardio-oncology: results from the COVID-19 International Collaborative Network survey by Sadler, Diego, DeCara, Jeanne M., Herrmann, Joerg, Arnold, Anita, Ghosh, Arjun K., Abdel-Qadir, Husam, Yang, Eric H., Szmit, Sebastian, Akhter, Nausheen, Leja, Monika, Silva, Carolina Maria Pinto Domingues Carv, Raikhelkar, Jayant, Brown, Sherry-Ann, Dent, Susan, O’Quinn, Rupal, Thuny, Franck, Moudgil, Rohit, Raez, Luis E., Okwuosa, Tochukwu, Daniele, Andres, Bauer, Brenton, Kondapalli, Lavanya, Ismail-Khan, Roohi, Lax, Jorge, Blaes, Anne, Nahleh, Zeina, Elson, Leah, Baldassarre, Lauren A., Zaha, Vlad, Rao, Vijay, Lara, Daniel Sierra, Skurka, Kerry

“…Background Re-allocation of resources during the COVID-19 pandemic has resulted in delays in care delivery to patients with cardiovascular disease and cancer…”
Get full text

A comparative pharmacodynamic study of ticagrelor versus clopidogrel and ticagrelor in patients undergoing primary percutaneous coronary intervention: the CAPITAL RELOAD study by Hibbert, Benjamin, Maze, Ronnen, Pourdjabbar, Ali, Simard, Trevor, Ramirez, F Daniel, Moudgil, Rohit, Blondeau, Melissa, Labinaz, Marino, Dick, Alexander, Glover, Christopher, Froeschl, Michael, Marquis, Jean-François, So, Derek Y F, Le May, Michel R

“…In patients undergoing primary percutaneous coronary intervention (PPCI) ticagrelor is superior to clopidogrel in reducing cardiovascular events. This study…”
Get full text

Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway by Moudgil, Rohit, Samra, Gursharan, Ko, Kyung Ae, Vu, Hang Thi, Thomas, Tamlyn N, Luo, Weijia, Chang, Jiang, Reddy, Anilkumar K, Fujiwara, Keigi, Abe, Jun-Ichi

“…Diastolic dysfunction is condition of a stiff ventricle and a function of aging. It causes significant cardiovascular mortality and morbidity, and in fact,…”
Get full text

In vivo gene transfer of the O2-Sensitive potassium channel kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats by POZEG, Zlatko I, MICHELAKIS, Evangelos D, SULTANIAN, Richard, KOSHAL, Arvind, ARCHER, Stephen L, MCMURTRY, M. Sean, THEBAUD, Bernard, WU, Xi-Chen, DYCK, Jason R. B, HASHIMOTO, Kyoko, WANG, Shaohua, MOUDGIL, Rohit, HARRY, Gwyneth

“…Alveolar hypoxia acutely elicits pulmonary vasoconstriction (HPV). Chronic hypoxia (CH), despite attenuating HPV, causes pulmonary hypertension (CH-PHT). HPV…”
Get full text