Search Results - "MOTYKA, S"

The Structure of a Human Type III Fcγ Receptor in Complex with Fc by Radaev, Sergei, Motyka, Shawn, Fridman, Wolf-Herman, Sautes-Fridman, Catherine, Sun, Peter D.

“…Fcγ receptors mediate antibody-dependent inflammatory responses and cytotoxicity as well as certain autoimmune dysfunctions. Here we report the crystal…”
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Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand by Sun, Peter D, Boyington, Jeffrey C, Motyka, Shawn A, Schuck, Peter, Brooks, Andrew G

“…Target cell lysis is regulated by natural killer (NK) cell receptors that recognize class I MHC molecules. Here we report the crystal structure of the human…”
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Co-amplification of a novel gene, NAG, with the N-myc gene in neuroblastoma by WIMMER, K, ZHU, X. X, LAMB, B. J, KUICK, R, AMBROS, P. F, KOVAR, H, THORAVAL, D, MOTYKA, S, ALBERTS, J. R, HANASH, S. M

“…Substantial evidence implicates amplification of the N-myc gene with aggressive tumor growth and poor outcome in neuroblastoma. However some evidence suggests…”
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Replication of kinetoplast DNA: an update for the new millennium by MORRIS, James C, DREW, Mark E, KLINGBEIL, Michele M, MOTYKA, Shawn A, SAXOWSKY, Tina T, ZEFENG WANG, ENGLUND, Paul T

“…In this review we will describe the replication of kinetoplast DNA, a subject that our lab has studied for many years. Our knowledge of kinetoplast DNA…”
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RNAi libraries and kinetoplast DNA by Englund, P T, Agbo, E E C, Lindsay, M E, Liu, B, Liu, Y, Motyka, S A, Yildirir, G, Zhao, Z

“…African trypanosomes have a remarkable mitochondrial DNA termed kDNA (kinetoplast DNA) that contains several thousands of topologically interlocked DNA rings…”
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Unlocking the Secrets of Trypanosome Kinetoplast DNA Network Replication by Klingbeil, Michele M., Drew, Mark E., Liu, Yanan, Morris, James C., Motyk, Shawn A., Saxowsky, Tina T., Wang, Zefeng, Englund, Paul T.

“…Trypanosomatids are a ubiquitous and ancient lineage of parasitic protozoa that infect diverse species of insects, animals, and plants. However, they are best…”
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Development of a Recombinant Bacterial Expression System for the Active Form of a Human Transforming Growth Factor β Type II Receptor Ligand Binding Domain by Boesen, Christian C., Motyka, Shawn A., Patamawenu, Apisit, Sun, Peter D.

“…Expression systems have been designed to test the suitability of expressing the high cysteine containing extracellular domain (residues 1–136) of human…”
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Mitochondrial origin-binding protein UMSBP mediates DNA replication and segregation in trypanosomes by Milman, Neta, Motyka, Shawn A, Englund, Paul T, Robinson, Derrick, Shlomai, Joseph

“…Kinetoplast DNA (kDNA) is the remarkable mitochondrial genome of trypanosomatids. Its major components are several thousands of topologically linked DNA…”
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Crystallization and preliminary crystallographic studies of human TGF-β type II receptor ligand-binding domain by Boesen, Christian C., Motyka, Shawn A., Patamawenu, Apisit, Sun, Peter D.

“…Three constructs (residues 15–136, 22–136 and 27–136) of the truncated extracellular domain of human transforming growth factor β type II receptor (TBRII) were…”
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Fellowship of the rings: the replication of kinetoplast DNA by Liu, Beiyu, Liu, Yanan, Motyka, Shawn A., Agbo, Eddy E.C., Englund, Paul T.

“…Kinetoplastid protozoa such as trypanosomes and Leishmania are important because they cause human disease. These parasites are named after one of their most…”
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N-myc Modulates Expression of p73 in Neuroblastoma by Zhu, Xiaoxiang, Wimmer, Katharina, Kuick, Rork, Lamb, Barbara J., Motyka, Stephanie, Jasty, Rama, Castle, Valerie P., Hanash, Samir M.

“…The human p73 gene is a homolog of p53, which has been localized to chromosome 1p36 in a region that is frequently deleted in neuroblastoma. Transfection of…”
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The structure of a human type III Fcgamma receptor in complex with Fc by Radaev, S, Motyka, S, Fridman, W H, Sautes-Fridman, C, Sun, P D

“…Fcgamma receptors mediate antibody-dependent inflammatory responses and cytotoxicity as well as certain autoimmune dysfunctions. Here we report the crystal…”
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Multiple Mitochondrial DNA Polymerases in Trypanosoma brucei by Klingbeil, Michele M., Motyka, Shawn A., Englund, Paul T.

“…Kinetoplast DNA (kDNA), the unusual mitochondrial DNA of Trypanosoma brucei, is a network containing thousands of catenated circles. Database searching for a…”
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RNA interference for analysis of gene function in trypanosomatids by Motyka, Shawn A, Englund, Paul T

“…Gene-specific silencing by RNA interference is a valuable tool for analysis of gene function in the protozoan parasite Trypanosoma brucei. The development of…”
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Deep learning to detect acute respiratory distress syndrome on chest radiographs: a retrospective study with external validation by Sjoding, Michael W, Taylor, Daniel, Motyka, Jonathan, Lee, Elizabeth, Co, Ivan, Claar, Dru, McSparron, Jakob I, Ansari, Sardar, Kerlin, Meeta Prasad, Reilly, John P, Shashaty, Michael G S, Anderson, Brian J, Jones, Tiffanie K, Drebin, Harrison M, Ittner, Caroline A G, Meyer, Nuala J, Iwashyna, Theodore J, Ward, Kevin R, Gillies, Christopher E

“…Acute respiratory distress syndrome (ARDS) is a common, but under-recognised, critical illness syndrome associated with high mortality. An important factor in…”
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Effects of RNA Interference of Trypanosoma brucei Structure-specific Endonuclease-I on Kinetoplast DNA Replication by Liu, Yanan, Motyka, Shawn A., Englund, Paul T.

“…Kinetoplast DNA, the mitochondrial DNA of trypanosomatid protozoa, is a network containing several thousand topologically interlocked DNA minicircles…”
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Integration of pZJM library plasmids into unexpected locations in the Trypanosoma brucei genome by Motyka, Shawn A., Zhao, Zhixing, Gull, Keith, Englund, Paul T.

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Evidence of disparity in the application of quality improvement efforts for the treatment of acute myocardial infarction: The American College of Cardiology's Guidelines Applied in Practice Initiative in Michigan by Olomu, Adesuwa B., MD, MS, Grzybowski, Mary, PhD, MPH, Ramanath, Vijay S., MD, Rogers, Adam M., MD, Vautaw, Bonnie Motyka, MS, Chen, Benrong, PhD, Roychoudhury, Canopy, PhD, Jackson, Elizabeth A., MD, MPH, Eagle, Kim A., MD

“…Background Racial disparities exist in the management of patients with cardiovascular disease in the United States. The aim of the study was to evaluate if a…”
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